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Chromosome structure and function

Characterization of DNA methylation in PBMCs and donor-matched iPSCs shows age-related methylation is reset during stem cell reprogramming

Xylena Reed, Cory A. Weller, Sara Saez-Atienzar, Alexandra Beilina, Sultana Solaiman, Makayla Portley, Mary Kaileh, Roshni Roy, Jinhui Ding, A. Zenobia Moore, D. Thad Whitaker, Bryan J. Traynor, Luigi Ferrucci, J. Raphael Gibbs, Sonja W. Scholz, Mark R. Cookson

published 08 Sep 2026

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Targeting telomeres in brain vasculature does not impede initiation and progression of glioblastoma

Amparo Sánchez-Hernández, Sonia Burgaz, Jessica Louzame-Ruano, Óscar Laguía, Giuseppe Bosso, Rosa Serrano, Ana Cayuela López, Juana María Flores, Paula Martínez, Maria A. Blasco

published 12 Aug 2026

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A role for nucleosome remodellers during resection of deprotected telomeres in yeast

Anja M. Deiser, Caitlyn Agar, Juan de Dios Barba Tena, Boris Pfander

published 10 Jul 2026

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A multi-product, multi-period vaccine supply chain network planning with injection centers and storage conditions

Reyhane Heydarpour, Hadi Mokhtari, Saeed Dehnavi

published 09 Jul 2026

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Minimal mutational requirements for conversion of a telomere resolvase into a Cre-like site-specific recombinase

Shu Hui Huang, Kerri Kobryn

published 29 May 2026

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Single-cell transcriptomics of bronchoalveolar lavage reveals divergent macrophage subpopulations and trajectories in interstitial lung disease

Lai-Ying Zhang, Peter C. Allen, Viviana P. Lutzky, Simon H. Apte, Penny L. Groves, Maxine E. Tan, Tharushi De Silva, Eleanor R. Spenceley, Rachael A. McCloy, Quan H. Nguyen, Joseph E. Powell, Daniel C. Chambers, Brendan J. O’Sullivan

published 29 Apr 2026

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B chromosome retrotransposed sequences persist through speciation, contributing to genomic and regulatory innovations in the fish genus Psalidodon (Characiformes, Acestrorhamphidae)

Lucas F. Lasmar, Mateus R. Vidal, Pamela C. F. Nadai, Rodrigo Zeni dos Santos, Raquel da Costa Machado, Ricardo Utsunomia, Francisco J. Ruiz-Ruano, Alexander Suh, Claudio Oliveira, Duilio M. Z. A. Silva, Fausto Foresti

published 02 Jan 2026

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Single sperm karyotyping of testicular sperm in non-obstructive and obstructive azoospermia using next generation sequencing

Sumiko Sueyoshi, Akifumi Ijuin, Hiroe Ueno, Ai Miyakoshi, Haru Hamada, Misaki Toda, Naoki Tsuchiya, Miki Tanoshima, Mayuko Kurumizaka, Marina Saito, Yuki Oike, Kazumi Takeshima, Teppei Takeshima, Shinnosuke Kuroda, Yasushi Yumura, Shin Saito, Ryoko Asano, Taichi Mizushima, Etsuko Miyagi, Hideya Sakakibara, Hiroki Kurahashi, Akira Yanagihara, Mariko Murase, Tomonari Hayama

published 05 Dec 2025

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Integrative genomic characterization of five Pediococcus acidilactici strains reveals differing probiotic safety profiles

Yuda Disastra, Thidathip Wongsurawat, Piroon Jenjaroenpun, David John Hampson, Ratchnida Kamwa, Nuvee Prapasarakul

published 30 Sep 2025

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Association of ageing-related biomarkers with peripheral neuropathy in colorectal cancer patients up to 2 years after diagnosis

Wenbo Wu, Floortje Mols, Cynthia S. Bonhof, Lou Maas, Frederik-Jan van Schooten, Geja J. Hageman, Lonneke V. van de Poll-Franse, Dounya Schoormans

published 26 Sep 2025

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Infection and telomere length: A systematic review

Louis Tunnicliffe, Rutendo Muzambi, Jonathan W. Bartlett, Laura D. Howe, Khalid A. Basit, Kwabena Asare, Georgia Gore-Langton, Kathryn E. Mansfield, Veryan Codd, Charlotte Warren-Gash

published 23 Sep 2025

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Potential role of miR-29b from mesenchymal stromal cell-derived extracellular vesicles in leukemic cell progression

Heejei Yoon, Silvia Park, Yong-Rim Kwon, Yoo-Jin Kim

published 10 Sep 2025

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Conversion of a telomere resolvase into a Cre-like site-specific recombinase

Shu Hui Huang, Mahrokh Balouchi, Kerri Kobryn

published 17 Jul 2025

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