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Chondrocytes

HIF-2α drives osteoarthritis progression via suppression of the HDAC4-ATF4-CHOP signaling axis

Pinpin Jiang, Hang Wang, Yujia Li, Yuanyu Zhang, Jingrui Huang, Yukun Xu, Dahai Rong, Danni Ruan, Yao Wang, Jie Yuan, Pengcui Li

published 18 Jun 2026

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Screening disease feature genes and analyzing correlations with immune cell infiltration in knee osteoarthritis chondrocytes based on multiple machine learning algorithms

Jing-le Zhuge, Xi-yong Li, Yong-le Wang, Juan-fen Ma

published 16 Jun 2026

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Molecular characterization of superficial zone chondrocytes under pro-inflammatory and biomechanical stress conditions

Fengrui Liu, Xueting Ding, Pengcui Li, Jie Yuan, Li Guo, Sen Zhao, Gaige Wu, Xiaochun Wei

published 12 Jun 2026

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Single-cell RNA sequencing of healthy and diseased rat temporomandibular joint condyle cartilage

Sara Trbojevic, Xudong Dong, Robert Lafyatis, Michael S. Gold, Juan M. Taboas, Alejandro J. Almarza

published 30 Apr 2026

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Study on the therapeutic effect of eggshell membrane on osteoarthritis in rats

Mingming Pan, Yanhua Shen, Jiayu Wu, Chaonan Liu, Meihong Zhu, Zhengyu Zhou

published 03 Apr 2026

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Alterations in bone malformation in the absence of the endosomal SNAREs Vti1a and Vti1b

Simone Schmücker, Susanne Schöning, Christiane Wiegand, Sascha Michael Höfling, Christian Bollmann, Judith Koliwer, Gabriele Fischer von Mollard

published 16 Mar 2026

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Single-cell omics reveals arg-1 as a key regulator of age-dependent macrophage-mediated cartilage repair

JianJun Chu, Zhengfa Wen, Wenying Wu, Shoukun Wu

published 10 Mar 2026

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Chondroitin sulfate alleviates osteoarthritis by upregulating HSPA8 to inhibit chondrocyte ferroptosis

Jiayang Jiang, Yangyang Xu, Tianming Dai, Junyan Chen, Siming Li, Qingqi Meng

published 19 Feb 2026

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Investigating insulin’s role in regulating local aromatase in growth plate development

Sicui Hu, MinMin Xue, Yao Dong, Cheng Li, Lingyan Qiao, Rongxiu Zheng

published 02 Dec 2025

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SAT1 promotes the progression of OA by regulating TRIM33-mediated p53 acetylation to enhance ferroptosis

Jiexiang Yang, Jing Jiang, Jing Wang, Lin Luo

published 08 Oct 2025

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Modeling treatment of osteoarthritis with standard therapy and senolytic drugs

Nourridine Siewe, Avner Friedman

published 22 Sep 2025

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Curcumin inhibits ferroptosis through dessuccinylation of SIRT5-associated ACSL4 protein, and plays a chondroprotective role in osteoarthritis

Yong Xu, Yongxia Li, Lei Liu, Qingling Jing, Xiaojian Ye

published 18 Aug 2025

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Exposure to maternal nicotine in utero and/or via lactation alters craniofacial development in mice

Amr Mohi, Emily L. Durham, Rajiv Kishinchand, James J. Cray Jr

published 01 Aug 2025

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