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Chondrocytes

Chondroitin sulfate alleviates osteoarthritis by upregulating HSPA8 to inhibit chondrocyte ferroptosis

Jiayang Jiang, Yangyang Xu, Tianming Dai, Junyan Chen, Siming Li, Qingqi Meng

published 19 Feb 2026

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Investigating insulin’s role in regulating local aromatase in growth plate development

Sicui Hu, MinMin Xue, Yao Dong, Cheng Li, Lingyan Qiao, Rongxiu Zheng

published 02 Dec 2025

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SAT1 promotes the progression of OA by regulating TRIM33-mediated p53 acetylation to enhance ferroptosis

Jiexiang Yang, Jing Jiang, Jing Wang, Lin Luo

published 08 Oct 2025

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Modeling treatment of osteoarthritis with standard therapy and senolytic drugs

Nourridine Siewe, Avner Friedman

published 22 Sep 2025

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Curcumin inhibits ferroptosis through dessuccinylation of SIRT5-associated ACSL4 protein, and plays a chondroprotective role in osteoarthritis

Yong Xu, Yongxia Li, Lei Liu, Qingling Jing, Xiaojian Ye

published 18 Aug 2025

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Exposure to maternal nicotine in utero and/or via lactation alters craniofacial development in mice

Amr Mohi, Emily L. Durham, Rajiv Kishinchand, James J. Cray Jr

published 01 Aug 2025

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Human umbilical cord mesenchymal stem cells decellular matrix alleviates chondrocyte senescence by inhibiting the STING-NF-κB pathway

Yuelong Zhang, Xunshan Ren, Huangming Zhuang, Huajie Li, Miradj Siddick Adam, Rongling Feng, Junming Zhu, Panghu Zhou

published 26 Jun 2025

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Alpinetin protects against iron overload related osteoarthritis via NRF2/HO-1 pathway

Dongling Cai, Zhaofeng Pan, Shaocong Li, Qi He, Baihao Chen, Miao Li, Jiacong Xiao, Fancheng Wan, Haibin Wang, Chi Zhou

published 02 Jun 2025

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FGF18 induces chondrogenesis and anti-osteoarthritic effects in a mouse model for TMJ degeneration

Flavia Gomes Velasque Gama, Christina Casciani, Eliane Hermes Dutra

published 24 Apr 2025

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Intermittent hypoxic stimulation promotes efficient expression of Hypoxia-inducible factor-1α and exerts a chondroprotective effect in an animal osteoarthritis model

Ryota Cha, Shuji Nakagawa, Yuji Arai, Atsuo Inoue, Naoki Okubo, Yuta Fujii, Kenta Kaihara, Kei Nakamura, Tsunao Kishida, Osam Mazda, Kenji Takahashi

published 01 Apr 2025

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Screening potential anti-osteoarthritis compounds using molecular docking based on MAPK and NFκB pathways and validating their anti-osteoarthritis effect

Tian-Wang Zhu, Yu Zheng, Rui-Xin Li

published 25 Mar 2025

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Non-targeted metabolomic study in plasma in rats with post-traumatic osteoarthritis model

Peng-fei Han, Xi-yong Li, Chang-peng Zhang, Chang-sheng Liao, Wei-wei Wang, Yuan Li

published 12 Mar 2025

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Dehydroepiandrosterone inhibits ADAMTS expression via an ERK-dependent mechanism in chondrocytes

Kai Huang, Lin Cheng, Cheng Jiang, Chunwei Zheng, Haili Cai

published 22 Nov 2024

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