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Cell viability testing

L-(+)-Ergothioneine ameliorates preeclampsia-associated vascular endothelial dysfunction by modulating the Nrf2-PPARγ-sFlt-1 axis

Jingjin Gong, Yan Liu, Qingju Meng, Junwei Wu, Fang Chen, Yanwen Xu, Yanqiu Li, Qiwei Luo

published 18 Sep 2026

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From in silico prediction to experimental validation: Identification of drugs and novel synergistic combinations that inhibit growth of inflammatory breast cancer cells

Esraa A. Salim, Xiaojia Ji, Michael Tarpley, Maria S. Dixon, Weifan Zheng, John E. Scott, Kevin P. Williams

published 16 Sep 2026

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A bioactivity-leveling approach for component-specific evaluation in natural product extracts: Optimizing SARS-CoV-2 antiviral screening by controlling for pheophorbide A

Corinna Urmann, Yvonne Gmach, Niklas Hofer, Nina Vahekeni, Jonas Stehlin, Yannick Geissmann, Andreas Lardos, Olivier Engler, Evelyn Wolfram

published 24 Aug 2026

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A 3-dimensional Resnet model for assessment of drug efficacy in 3D cancer models using optical coherence tomography

Gavrielle R. Untracht, Jan Kaminski, Eike Guldenring, Boye Schnack Nielsen, Kim Holmstrøm, Katrine Hommelhoff Jensen, Peter E. Andersen

published 24 Jul 2026

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Cocoa by-products extracts suppress viral replication and oxidative stress in chikungunya virus-infected cells

Sandra Johanna Morantes, Luisa Fernanda Daza, Alejandro Cáceres, Luis Felipe Gutiérrez, Martha Cecilia Rincón, Juan David Dereix, Félix Giovanni Delgado

published 22 Jul 2026

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THSD7B promotes tumor progression and is associated with prognosis in gastric adenocarcinoma

Xinying Quan, Wei Cheng, Yao Pu, Hong Deng

published 12 Jun 2026

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Comprehensive quantum chemical analysis, vibrational spectroscopy, molecular docking, ADMET, and in vitro validation studies of hydroxychloroquine-MRGPRX2 complex in IDH-wildtype glioblastoma

Aliye Demet Demirag, Rahmi Atil Aksoy, Gizem Akman, Vildan Kaya, Mustafa Yildirim

published 21 May 2026

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Inhibition of purine nucleoside and nucleobase transporters by tyrosine kinase inhibitors

Nayiar Shahid, Chan H. Kim, Kerrylei B. Jabilona, Khanh H. Nguyen, Nicholas M. Ruel, James R. Hammond

published 15 May 2026

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The role of SPP1 in evaluating the prognosis, immune infiltration, and drug sensitivity of hepatocellular carcinoma

Kai Cui, Xia Li, Yongrun Li, Zhong Li, Du Wang, Xinhong Wang, Shuxin Qin, Junjie Li, Jiaye Long

published 22 Apr 2026

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Strategic selection of MDM2 inhibitors enhances the efficacy of FAK inhibition in mesothelioma based on TP53 genotype

Xuerao Ning, Thảo Thi Thanh Nguyễn, Takao Morinaga, Yuji Tada, Hideaki Shimada, Kenzo Hiroshima, Naoto Yamaguchi, Masatoshi Tagawa

published 23 Feb 2026

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Bioassay-guided fractionation and identification of wound healing active compounds from Khaya senegalensis leaves

Akrimi Najihah Mohd Khamil, Norizamimie Nordin, Mohamad Afiq Aizuddin Rosdi, Mohamad Faiz Hamzah, Mohd Hasnan Mohd Noor, Siti Zuraidah Mohamad Zobir, Amyra Amat Sain, Mohammad Tasyriq Che Omar, Mohamad Nurul Azmi Mohamad Taib, Ayunni Salihah Zalaludin

published 02 Feb 2026

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Development of a CYP2D6-enhanced HepaRG cell model with improved CYP2D6 metabolic capacity

Chizuka Obara, Yohei Iizaka, Akari Mine, Yojiro Anzai, Masako Tada, Shinpei Yamaguchi

published 29 Dec 2025

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Synergistic enhancement of AAV gene delivery in 2D cells and 3D organoids using polybrene and hydroxychloroquine

Hyeon-Jin Na, Yongbo Shin, Seung-Hyun Kim, Seung Pil Jang, Myung Jin Son, Yong Min Choi, Hyeon Gyeol Jeon, Ok-Seon Kwon, Kyung-Sook Chung

published 14 Nov 2025

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