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Cell processes

CRISPR/Cas9 mediated ENT2 gene knockout altered purine catabolic pathway and induced apoptosis in colorectal cell lines

Safaa M. Naes, Sharaniza Ab-Rahim, [ ... ], Amirah Abdul Rahman

Utilizing Multi-omics analysis to elucidate the role of mitochondrial gene defects in Gastric cancer progression

Jie Chu, Hanying Song, [ ... ], Bo Deng

Alpinetin protects against iron overload related osteoarthritis via NRF2/HO-1 pathway

Dongling Cai, Zhaofeng Pan, [ ... ], Chi Zhou

Comparative proteomics of HepG2 cells reveals NGLY1 as an important regulator of ferroptosis resistance and iron uptake

Stuart Emmerson, Haruhiko Fujihira, [ ... ], Tadashi Suzuki

Effects of combination therapy of a CDK4/6 and MEK inhibitor in diffuse midline glioma preclinical models

Yusuke Tomita, Gabrielle Link, [ ... ], Oren J. Becher

Cell death and iron deposition in the liver in two murine models of acute radiation syndrome

Dmitry T. Bradfield, John E. Slaven, [ ... ], Regina M. Day

CPI203, a BET inhibitor, down-regulates a consistent set of DNA synthesis genes across a wide array of glioblastoma lines

Matthew C. Garrett, Troy Carnwath, [ ... ], David R. Plas

CUB domain-containing protein 1 signaling dysregulates gemcitabine metabolism contributing to therapeutic resistance in T24 cells

Kun-Lin Hsieh, Kuan-Hua Huang, [ ... ], Huei-Sheng Huang

Peptidylarginine deiminase 4 deficiency alleviates hypoxia/reoxygenation-induced cardiomyocyte injury

Matthias Mand, Michelle Holthaus, [ ... ], Adnana Paunel-Görgülü

Identification and validation of oxidative stress-related genes for the diagnosis of sepsis-induced acute lung injury

Xue Fu, Jiawei Dong, [ ... ], Meng Zhang

Lycopene inhibits ER stress and apoptosis while modulating PI3K/AKT and enhancing antioxidant and anti-apoptotic proteins

Lijun Zheng, Hui Zhang, Yuchao Sun

Synergistic effects of notoginsenoside R1 and saikosaponin B2 in atherosclerosis: A novel approach targeting PI3K/AKT/mTOR pathway and macrophage autophagy

Yihua Wang, Qing Liao, [ ... ], Chunyang Zhou

In vitro and in vivo approaches demonstrating the antiproliferative activity of pomegranate seed proteins and peptides on breast cancer

Miriam Guzmán-Lorite, Laura Muñoz-Moreno, [ ... ], María Concepción García

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