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Cell processes

Lycopene inhibits ER stress and apoptosis while modulating PI3K/AKT and enhancing antioxidant and anti-apoptotic proteins

Lijun Zheng, Hui Zhang, Yuchao Sun

published 23 Dec 2025

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Therapeutic mechanisms of genistein in ischemic stroke: A systematic review of in vivo and in vitro studies

Nurin Yasmin Mohd Khairudin, Awla Mohd Azraai, Rosfaiizah Siran, Nasibah Azme

published 23 Dec 2025

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Effects of combination therapy of a CDK4/6 and MEK inhibitor in diffuse midline glioma preclinical models

Yusuke Tomita, Gabrielle Link, Yi Ge, Emma R. H. Gold, Anna Racanelli, Herminio Joey Cardona, Megan Romero, Samantha Gadd, Jun Watanabe, Eita Uchida, Rintaro Hashizume, Nozomu Takata, Gonzalo Pinero, Dolores Hambardzumyan, Ivan Spasojevic, Guo Hu, Tammy Hennika, Daniel J. Brat, Adam L. Green, Oren J. Becher

published 22 Dec 2025

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Potential association of certain microRNA gene polymorphisms with recurrent pregnancy loss susceptibility in Saudi women

Aya Rabaa, Afrah Alkuriji, Aishah Kabbi, Samiah Almalki, Zainab Almasawi, Maha Daghestani, Hana Hakami, Jawaher Alzahrani

published 19 Dec 2025

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Overexpression of PTPRCAP inhibits biological function of lung adenocarcinoma through apoptosis pathway

Yuting Yang, Baoshan Zhao, Yingjie Jiang, Xiaoli Han, Jingtao Huang, Guangrui Sun, Zongying Liang

published 18 Dec 2025

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Genomic and enzymatic insights into α-amylase-producing Bacillus spizizenii strains isolated from Isfahan province, Iran

Batoul Al Sharif, Mohammad Mehdi Golchini, Aboozar Soorni, Rahim Mehrabi

published 18 Dec 2025

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Comprehensive analysis of genes associated with necroptosis and pyroptosis in intestinal ischemia-reperfusion injury

Shuang Bao, YanBo Sun, YiChen Hu, XueFen Lei, YuanPei Zhao, WeiMing Li

published 16 Dec 2025

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Unravelling drought stress adaptation in sugarcane interspecific hybrids: A multi-level analysis

Lakshmi Kasirajan, Sheelamary Sebastiar, Ramvannish Muthukumar, Rachel Lissy Vargheese, Karpagam Elumalai, Keerthana Kamaraj, Rabisha Valiyaparambth, Suganya Angannan, Annadurai Ayyadurai, Gomathi Raju, Selvi Athiappan, Devakumar Krishnamoorthy, Gayathri Kanagavel, Nandini Karthikeyan, Palanivel Gopal Santhosh Kumar, Indusha Yazhini Sankararaj

published 12 Dec 2025

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The protective influence of Astragalus on rat models of preeclampsia

Lijun Yang, Huiniu Hao, Xinhuan Zhang, Xiaorui Ren, Miao Xu, Nan Zhang, Yudan Zhang, Hailan Yang

published 12 Dec 2025

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Therapeutic mechanism of Pithecellobium clypearia Benth. on imiquimod-induced psoriasis revealed by tissue transcriptomics in mice

Xiyuan He, Yueting Mo, Peixin Shi, Yini Xu, Mingmei Zhou, Ting Zhang

published 12 Dec 2025

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Butyrate ameliorates DSS-induced ulcerative colitis in mice by facilitating autophagy in intestinal epithelial cells and modulating the gut microbiota through blocking the PI3K-AKT-mTOR pathway

Ruifang Li, Yan Sun, Drolma Kelsang, Mingzhi Feng, Hanhui Cai, Jun Zhang

published 11 Dec 2025

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PyUAT: An open-source Python framework for uncertainty-aware, efficient, and scalable model-driven cell tracking

Johannes Seiffarth, Katharina Nöh

published 11 Dec 2025

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Aotaphenazine, a rare hydrophenazine, targets topoisomerase II with anticancer efficacy: In silico to in vitro evidence

Ahmed M. Metwaly, Ibrahim H. Eissa, Wael M. Afifi, Eslam B. Elkaeed, Aisha A. Alsfouk, Ibrahim M. Ibrahim, Mohamed S. Abdelfattah

published 05 Dec 2025

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