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Cell potency

Reaching a cell monolayer at the end of hiPSC differentiation enhances neural crest lineage commitment

Filipa M. Duarte, Jeroen van de Peppel, Irene M.J. Mathijssen, Johan W. van Neck

published 04 Sep 2025

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The Wnt pathway induces a naïve-like subpopulation in primed stem cells, while NME7_AB leads to a homogeneous naïve-like population

Kevin R. Yi, Jac-Leen S.S. Nash, Mark G. Carter, Danica M. Walkley, Jiwon Jang, Benoit J. Smagghe, Andrew K. Stewart, Cynthia C. Bamdad

published 25 Jun 2025

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Non-viral derivation of induced pluripotent stem cells from the canine umbilical cord

Atsushi Yamazaki, Seiji Shiozawa, Yuko Koushige, Hirotaka Kondo, Hisashi Shibuya, Kazuya Edamura

published 18 Jun 2025

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Construction of a proximity labeling vector to identify protein-protein interactions in human stem cells

Rubens Gomes-Junior, Claudia Maria do Nascimento Moreira, Bruno Dallagiovanna

published 30 May 2025

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Screening for variable drug responses using human iPSC cohorts

Melpomeni Platani, Hao Jiang, Lindsay Davidson, Santosh Hariharan, Regis Doyonnas, Angus I. Lamond, Jason R. Swedlow

published 30 May 2025

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Stem cell culture conditions affect in vitro differentiation potential and mouse gastruloid formation

Marloes Blotenburg, Lianne Suurenbroek, Danique Bax, Joëlle de Visser, Vivek Bhardwaj, Luca Braccioli, Elzo de Wit, Antonius van Boxtel, Hendrik Marks, Peter Zeller

published 26 Mar 2025

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A NOTCH3 pathogenic variant influences osteogenesis and can be targeted by antisense oligonucleotides in induced pluripotent stem cells

Ernesto Canalis, Jungeun Yu, Lauren Schilling, Paymaan Jafar-nejad, Michele Carrer

published 03 Jan 2025

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A suboptimal OCT4-SOX2 binding site facilitates the naïve-state specific function of a Klf4 enhancer

Jack B. Waite, RuthMabel Boytz, Alexis R. Traeger, Torrey M. Lind, Koya Lumbao-Conradson, Sharon E. Torigoe

published 30 Sep 2024

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A secreted proteomic footprint for stem cell pluripotency

Philip A. Lewis, Edina Silajdžić, Helen Smith, Nicola Bates, Christopher A. Smith, Fabrizio E. Mancini, David Knight, Chris Denning, Daniel R. Brison, Susan J. Kimber

published 14 Jun 2024

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Tumor microenvironment restricts IL-10 induced multipotent progenitors to myeloid-lymphatic phenotype

Lisa Volk-Draper, Shaswati Athaiya, Maria Espinosa Gonzalez, Nihit Bhattarai, Andrew Wilber, Sophia Ran

published 19 Apr 2024

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Directed differentiation of hPSCs through a simplified lateral plate mesoderm protocol for generation of articular cartilage progenitors

Christopher A. Smith, Paul A. Humphreys, Mark A. Naven, Steven Woods, Fabrizio E. Mancini, Julieta O’Flaherty, Qing-Jun Meng, Susan J. Kimber

published 27 Jan 2023

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Simultaneous depletion of RB, RBL1 and RBL2 affects endoderm differentiation of human embryonic stem cells

Shota Nakanoh, Juned Kadiwala, Laetitia Pinte, Carola Maria Morell, An-Sofie Lenaerts, Ludovic Vallier

published 22 Nov 2022

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Role of heat shock protein 60 in primed and naïve states of human pluripotent stem cells

Hong Seo Choi, Hyun Min Lee, Min Kyu Kim, Chun Jeih Ryu

published 09 Jun 2022

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