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Cell fusion

The SQSTM1-NUP214 fusion protein interacts with Crm1, activates Hoxa and Meis1 genes, and drives leukemogenesis in mice

Catherine P. Lavau, Waitman K. Aumann, Sei-Gyung K. Sze, Veerain Gupta, Katelyn Ripple, Sarah A. Port, Ralph H. Kehlenbach, Daniel S. Wechsler

published 28 Apr 2020

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INCB054828 (pemigatinib), a potent and selective inhibitor of fibroblast growth factor receptors 1, 2, and 3, displays activity against genetically defined tumor models

Phillip C. C. Liu, Holly Koblish, Liangxing Wu, Kevin Bowman, Sharon Diamond, Darlise DiMatteo, Yue Zhang, Michael Hansbury, Mark Rupar, Xiaoming Wen, Paul Collier, Patricia Feldman, Ronald Klabe, Krista A. Burke, Maxim Soloviev, Christine Gardiner, Xin He, Alla Volgina, Maryanne Covington, Bruce Ruggeri, Richard Wynn, Timothy C. Burn, Peggy Scherle, Swamy Yeleswaram, Wenqing Yao, Reid Huber, Gregory Hollis

published 21 Apr 2020

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Cryopreservation method for spheroids and fabrication of scaffold-free tubular constructs

Kenichi Arai, Daiki Murata, Shoko Takao, Ana Raquel Verissiomo, Koichi Nakayama

published 02 Apr 2020

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Multimerization strategies for efficient production and purification of highly active synthetic cytokine receptor ligands

Sofie Mossner, Hoang T. Phan, Saskia Triller, Jens M. Moll, Udo Conrad, Jürgen Scheller

published 01 Apr 2020

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Reactive oxygen species from mitochondria impacts trophoblast fusion and the production of endocrine hormones by syncytiotrophoblasts

O’Llenecia S. Walker, Rehginald Ragos, Michael K. Wong, Mohamed Adam, Anson Cheung, Sandeep Raha

published 24 Feb 2020

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Design and assessment of TRAP-CSP fusion antigens as effective malaria vaccines

Chafen Lu, Gaojie Song, Kristin Beale, Jiabin Yan, Emma Garst, Juan Feng, Emily Lund, Flaminia Catteruccia, Timothy A. Springer

published 22 Jan 2020

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A substitution mutation in a conserved domain of mammalian acetate-dependent acetyl CoA synthetase 2 results in destabilized protein and impaired HIF-2 signaling

Jason S. Nagati, Min Xu, Trent Garcia, Sarah A. Comerford, Robert E. Hammer, Joseph A. Garcia

published 14 Nov 2019

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Serial block-face scanning electron microscopy reveals neuronal-epithelial cell fusion in the mouse cornea

Justin A. Courson, Ian Smith, Thao Do, Paul T. Landry, Aubrey Hargrave, Ali R. Behzad, Sam D. Hanlon, Rolando E. Rumbaut, C. Wayne Smith, Alan R. Burns

published 13 Nov 2019

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A tailored approach to fusion transcript identification increases diagnosis of rare inherited disease

Gavin R. Oliver, Xiaojia Tang, Laura E. Schultz-Rogers, Noemi Vidal-Folch, W. Garrett Jenkinson, Tanya L. Schwab, Krutika Gaonkar, Margot A. Cousin, Asha Nair, Shubham Basu, Pritha Chanana, Devin Oglesbee, Eric W. Klee

published 02 Oct 2019

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Mitochondrial fragmentation and network architecture in degenerative diseases

Syed I. Shah, Johanna G. Paine, Carlos Perez, Ghanim Ullah

published 26 Sep 2019

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Quantitative detection of ALK fusion breakpoints in plasma cell-free DNA from patients with non-small cell lung cancer using PCR-based target sequencing with a tiling primer set and two-step mapping/alignment

Kei Kunimasa, Kikuya Kato, Fumio Imamura, Yoji Kukita

published 12 Sep 2019

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Display of malaria transmission-blocking antigens on chimeric duck hepatitis B virus-derived virus-like particles produced in Hansenula polymorpha

David Wetzel, Jo-Anne Chan, Manfred Suckow, Andreas Barbian, Michael Weniger, Volker Jenzelewski, Linda Reiling, Jack S. Richards, David A. Anderson, Betty Kouskousis, Catherine Palmer, Eric Hanssen, Gerhard Schembecker, Juliane Merz, James G. Beeson, Michael Piontek

published 04 Sep 2019

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High expression of the vacuole membrane protein 1 (VMP1) is a potential marker of poor prognosis in HER2 positive breast cancer

Arsalan Amirfallah, Adalgeir Arason, Hjorleifur Einarsson, Eydis Thorunn Gudmundsdottir, Edda Sigridur Freysteinsdottir, Kristrun Audur Olafsdottir, Oskar Thor Johannsson, Bjarni Agnar Agnarsson, Rosa Bjork Barkardottir, Inga Reynisdottir

published 23 Aug 2019

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