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Cell death

Lycopene inhibits ER stress and apoptosis while modulating PI3K/AKT and enhancing antioxidant and anti-apoptotic proteins

Lijun Zheng, Hui Zhang, Yuchao Sun

Therapeutic mechanisms of genistein in ischemic stroke: A systematic review of in vivo and in vitro studies

Nurin Yasmin Mohd Khairudin, Awla Mohd Azraai, Rosfaiizah Siran, Nasibah Azme

Effects of combination therapy of a CDK4/6 and MEK inhibitor in diffuse midline glioma preclinical models

Yusuke Tomita, Gabrielle Link, [ ... ], Oren J. Becher

Potential association of certain microRNA gene polymorphisms with recurrent pregnancy loss susceptibility in Saudi women

Aya Rabaa, Afrah Alkuriji, [ ... ], Jawaher Alzahrani

Overexpression of PTPRCAP inhibits biological function of lung adenocarcinoma through apoptosis pathway

Yuting Yang, Baoshan Zhao, [ ... ], Zongying Liang

Comprehensive analysis of genes associated with necroptosis and pyroptosis in intestinal ischemia-reperfusion injury

Shuang Bao, YanBo Sun, [ ... ], WeiMing Li

The protective influence of Astragalus on rat models of preeclampsia

Lijun Yang, Huiniu Hao, [ ... ], Hailan Yang

Therapeutic mechanism of Pithecellobium clypearia Benth. on imiquimod-induced psoriasis revealed by tissue transcriptomics in mice

Xiyuan He, Yueting Mo, [ ... ], Ting Zhang

Butyrate ameliorates DSS-induced ulcerative colitis in mice by facilitating autophagy in intestinal epithelial cells and modulating the gut microbiota through blocking the PI3K-AKT-mTOR pathway

Ruifang Li, Yan Sun, [ ... ], Jun Zhang

Aotaphenazine, a rare hydrophenazine, targets topoisomerase II with anticancer efficacy: In silico to in vitro evidence

Ahmed M. Metwaly, Ibrahim H. Eissa, [ ... ], Mohamed S. Abdelfattah

Exposure to polystyrene nanoparticles induce disruption of mitochondrial homeostasis and impairs trophoblast cell invasion and migration via MDM2/ROCK1 pathway

Dongdong Hao, Tengteng Ma, Xiaoping Li, Fengchun Gao

Nano-curcumin enhances the sensitivity of tamoxifen-resistant breast cancer cells via the Cyclin D1-DILA1 axis and the PI3K/AKT/mTOR pathway downregulation

Taraneh Givi, Fatemeh Mohajerani, [ ... ], Majid Sadeghizadeh

Exosomes from bone marrow mesenchymal stem cells protect melanocytes under vitiligo-related conditions through induction of NRF2/HO1 expression

Xuecheng Sun, Bo Huang, Gaobo Ruan, Aie Xu

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