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Cell death

Therapeutic mechanism of Pithecellobium clypearia Benth. on imiquimod-induced psoriasis revealed by tissue transcriptomics in mice

Xiyuan He, Yueting Mo, [ ... ], Ting Zhang

Butyrate ameliorates DSS-induced ulcerative colitis in mice by facilitating autophagy in intestinal epithelial cells and modulating the gut microbiota through blocking the PI3K-AKT-mTOR pathway

Ruifang Li, Yan Sun, [ ... ], Jun Zhang

Aotaphenazine, a rare hydrophenazine, targets topoisomerase II with anticancer efficacy: In silico to in vitro evidence

Ahmed M. Metwaly, Ibrahim H. Eissa, [ ... ], Mohamed S. Abdelfattah

Exposure to polystyrene nanoparticles induce disruption of mitochondrial homeostasis and impairs trophoblast cell invasion and migration via MDM2/ROCK1 pathway

Dongdong Hao, Tengteng Ma, Xiaoping Li, Fengchun Gao

Nano-curcumin enhances the sensitivity of tamoxifen-resistant breast cancer cells via the Cyclin D1-DILA1 axis and the PI3K/AKT/mTOR pathway downregulation

Taraneh Givi, Fatemeh Mohajerani, [ ... ], Majid Sadeghizadeh

Exosomes from bone marrow mesenchymal stem cells protect melanocytes under vitiligo-related conditions through induction of NRF2/HO1 expression

Xuecheng Sun, Bo Huang, Gaobo Ruan, Aie Xu

Autophagy regulates MK-2206-induced LDL receptor expression and cholesterol efflux pathways

Hilde Sundvold, Thea Bismo Strøm

Lysine p-nitroanilide impairs cellular energetics and potentiates statin-induced cytotoxicity in RD rhabdomyosarcoma cells

Johan Alvarado-Calderón, Guillermo Juárez-Vega, [ ... ], José Carlos Páez-Franco

Human umbilical cord-derived mesenchymal stem cells alleviate autoimmune hepatitis by inhibiting hepatic ferroptosis

Yaqin Li, Bing Liu, [ ... ], Wei V. Zheng

Identification of oxidative stress-responsive genes in recurrent miscarriage and their role in disease pathogenesis

Mian Wang, Lingling Zhu, Xiaoyan Cheng

Integrated multi-omics analysis reveals necroptosis-related biomarker BIRC3 for early diagnosis and therapeutic targeting in preeclampsia

Qingxia Lin, Peifeng Huang, [ ... ], Guili Shi

Mechanistic insight into the antidiabetic effects of Ficus hispida fruits: Inhibition of intestinal glucose absorption and pancreatic beta-cell apoptosis

Nusaiba Jahan, Noimul Hasan Siddiquee, [ ... ], AFM. Shahid Ud Daula

Anethole inhibits human U87 Glioma cell proliferation by inducing apoptosis via the PI3K/AKT pathway

Ahmed Abdullah Al Awadh, Elhashimi Eltayb Hassan, [ ... ], Mohammed Merae Alshahrani

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