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Cell death

Naringenin impairs mitochondrial function via ROS to induce apoptosis in tamoxifen resistant MCF-7 breast cancer cells

Lauren A. Eanes, Mayar Eldeeb, Darrell Storholt, Yashomati M. Patel

Elucidating the impact of Hypericum alpestre extract and L-NAME on the PI3K/Akt signaling pathway in A549 lung adenocarcinoma and MDA-MB-231 triple-negative breast cancer cells

Hayarpi Javrushyan, Mikayel Ginovyan, [ ... ], Nikolay Avtandilyan

Selective toxicity of ascorbic acid and hydrogen peroxide on human tenon cells without harming scleral cells in vitro: A possible alternative to non-selective mitomycin C?

Heiko Fuchs, Xiaonan Hu, [ ... ], Carsten Framme

Targeting NLRP3 and AIM2 signaling pathways by Viscosol alleviates metabolic dysregulations induced inflammatory responses in diabetic neuro- and nephropathy: An in silico and in vivo study

Summan Thahiem, Muhammad Ihsan, [ ... ], Imran Ullah

PM2.5 from automobile exhaust induces apoptosis in male rat germ cells via the ROS-UPR^mt signaling pathway

Cao Wang, Yingchi Zhao, [ ... ], Kaiyi Mao

Voluntarily wheel running protects doxorubicin-induced kidney injury by inhibiting oxidative stress through mitochondrial function

Xin Jiang, Zeyu Wang, [ ... ], Hongyu Jiang

Deubiquitination of epidermal growth factor receptor by ubiquitin-specific peptidase 54 enhances drug sensitivity to gefitinib in gefitinib-resistant non-small cell lung cancer cells

Mi Seong Kim, Min Seuk Kim

Inhibition of PHB1/PHB2 suppresses atherosclerotic plaque formation by interrupting PI3K/AKT/mTOR signaling

Mei Li, Xiaoyan Hu, [ ... ], Ying Gao

Curcumin induces mitochondrial dysfunction-associated oxidative DNA damage in ovarian cancer cells

Qi Bao, Zihan Wang, [ ... ], Weipei Zhu

Decoding oncogenic secrets of regulator of chromosome condensation 1: A breakthrough mechanistic evidence from breast and lung cancer models

Mohamed El-Tanani, Shakta Mani Satyam, [ ... ], Taher Hatahet

Effect of pyrroloquinoline quinone on skin aging in Bmi-1 KO mice and underlying mechanisms

Bin Li, Xiao Meng Yang, Xiong Ming Zhou, Yuan Qing Huang

Preparation of a solid dispersion of Euptox A and evaluation of its biological activity and safety

Haojun Li, Runa Zhao, [ ... ], Wenlong Chen

Mechanisms of adipocyte regulation: Insights from HADHB gene modulation

Chaoyun Yang, Shuzhe Wang, [ ... ], Zengwen Huang

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