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Catalysis

Determinants of Nucleotide-Binding Selectivity of Malic Enzyme

Ju-Yi Hsieh, Meng-Chun Chen, Hui-Chih Hung

Substrate Binding Process and Mechanistic Functioning of Type 1 11β-Hydroxysteroid Dehydrogenase from Enhanced Sampling Methods

Angelo D. Favia, Matteo Masetti, Maurizio Recanatini, Andrea Cavalli

Molecular Basis of NDM-1, a New Antibiotic Resistance Determinant

Zhongjie Liang, Lianchun Li, [ ... ], Hualiang Jiang

The Evolution of Enzyme Specificity in the Metabolic Replicator Model of Prebiotic Evolution

Balázs Könnyű, Tamás Czárán

Cell-free H-cluster Synthesis and [FeFe] Hydrogenase Activation: All Five CO and CN⁻ Ligands Derive from Tyrosine

Jon M. Kuchenreuther, Simon J. George, [ ... ], James R. Swartz

Screen for IDH1, IDH2, IDH3, D2HGDH and L2HGDH Mutations in Glioblastoma

Daniel Krell, Mawuelikem Assoku, [ ... ], Chiara Bardella

De Novo Enzyme Design Using Rosetta3

Florian Richter, Andrew Leaver-Fay, [ ... ], David Baker

Calcium/Calmodulin Dependent Protein Kinase II Bound to NMDA Receptor 2B Subunit Exhibits Increased ATP Affinity and Attenuated Dephosphorylation

John Cheriyan, Parimal Kumar, [ ... ], Ramakrishnapillai V. Omkumar

Discovering Conformational Sub-States Relevant to Protein Function

Arvind Ramanathan, Andrej J. Savol, [ ... ], Chakra S. Chennubhotla

Identification of Critical Residues of the Mycobacterial Dephosphocoenzyme A Kinase by Site-Directed Mutagenesis

Guneet Walia, Komatireddy Gajendar, Avadhesha Surolia

An Ash2L/RbBP5 Heterodimer Stimulates the MLL1 Methyltransferase Activity through Coordinated Substrate Interactions with the MLL1 SET Domain

Fang Cao, Yong Chen, [ ... ], Yali Dou

New Cobalt-Mediated Radical Polymerization (CMRP) of Methyl Methacrylate Initiated by Two Single-Component Dinuclear β-Diketone Cobalt (II) Catalysts

Feng Bao, Lingling Feng, [ ... ], Chunjie Yan

Catalytic Mechanism of Cellulose Degradation by a Cellobiohydrolase, CelS

Moumita Saharay, Hong Guo, Jeremy C. Smith

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