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Catalysis

Function of the Active Site Lysine Autoacetylation in Tip60 Catalysis

Chao Yang, Jiang Wu, Y. George Zheng

A Deadenylase Assay by Size-Exclusion Chromatography

Guang-Jun He, Yong-Bin Yan

Structures of Helicobacter pylori Shikimate Kinase Reveal a Selective Inhibitor-Induced-Fit Mechanism

Wen-Chi Cheng, Yen-Fu Chen, [ ... ], Wen-Ching Wang

Structure and Dynamics of the G121V Dihydrofolate Reductase Mutant: Lessons from a Transition-State Inhibitor Complex

Randall V. Mauldin, Paul J. Sapienza, Chad M. Petit, Andrew L. Lee

Isolation and Characterization of EstC, a New Cold-Active Esterase from Streptomyces coelicolor A3(2)

Guillaume Brault, François Shareck, [ ... ], Nicolas Doucet

A Catalytic Mechanism for Cysteine N-Terminal Nucleophile Hydrolases, as Revealed by Free Energy Simulations

Alessio Lodola, Davide Branduardi, [ ... ], Andrea Cavalli

The Origin of Large Molecules in Primordial Autocatalytic Reaction Networks

Varun Giri, Sanjay Jain

Domain Analysis Reveals That a Deubiquitinating Enzyme USP13 Performs Non-Activating Catalysis for Lys63-Linked Polyubiquitin

Yu-Hang Zhang, Chen-Jie Zhou, [ ... ], Hong-Yu Hu

Catalytic Properties of the Isolated Diaphorase Fragment of the NAD⁺-Reducing [NiFe]-Hydrogenase from Ralstonia eutropha

Lars Lauterbach, Zulkifli Idris, Kylie A. Vincent, Oliver Lenz

Structural and Biochemical Studies of Human 4-hydroxy-2-oxoglutarate Aldolase: Implications for Hydroxyproline Metabolism in Primary Hyperoxaluria

Travis J. Riedel, Lynnette C. Johnson, [ ... ], W. Todd Lowther

Determinants of Nucleotide-Binding Selectivity of Malic Enzyme

Ju-Yi Hsieh, Meng-Chun Chen, Hui-Chih Hung

Substrate Binding Process and Mechanistic Functioning of Type 1 11β-Hydroxysteroid Dehydrogenase from Enhanced Sampling Methods

Angelo D. Favia, Matteo Masetti, Maurizio Recanatini, Andrea Cavalli

Molecular Basis of NDM-1, a New Antibiotic Resistance Determinant

Zhongjie Liang, Lianchun Li, [ ... ], Hualiang Jiang

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