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Carcinogenesis

Disulfiram and copper combination therapy targets NPL4, cancer stem cells and extends survival in a medulloblastoma model

Riccardo Serra, Tianna Zhao, Sakibul Huq, Noah Leviton Gorelick, Joshua Casaos, Arba Cecia, Antonella Mangraviti, Charles Eberhart, Renyuan Bai, Alessandro Olivi, Henry Brem, Eric M. Jackson, Betty Tyler

published 03 Nov 2021

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Meta-Analysis illustrates possible role of lipopolysaccharide (LPS)-induced tissue injury in nasopharyngeal carcinoma (NPC) pathogenesis

David Z. Allen, Jihad Aljabban, Dustin Silverman, Sean McDermott, Ross A. Wanner, Michael Rohr, Dexter Hadley, Maryam Panahiazar

published 14 Oct 2021

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Use of relevancy and complementary information for discriminatory gene selection from high-dimensional gene expression data

Md Nazmul Haque, Sadia Sharmin, Amin Ahsan Ali, Abu Ashfaqur Sajib, Mohammad Shoyaib

published 06 Oct 2021

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Cancer-associated IDH mutations induce Glut1 expression and glucose metabolic disorders through a PI3K/Akt/mTORC1-Hif1α axis

Xun Liu, Kiyoshi Yamaguchi, Kiyoko Takane, Chi Zhu, Makoto Hirata, Yoko Hikiba, Shin Maeda, Yoichi Furukawa, Tsuneo Ikenoue

published 13 Sep 2021

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Virus–host interactions in carcinogenesis of Epstein-Barr virus-associated gastric carcinoma: Potential roles of lost ARID1A expression in its early stage

Hiroyuki Abe, Akiko Kunita, Yuya Otake, Teru Kanda, Atsushi Kaneda, Tetsuo Ushiku, Masashi Fukayama

published 01 Sep 2021

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Development of mammary cancer in γ-irradiated F₁ hybrids of susceptible Sprague-Dawley and resistant Copenhagen rats, with copy-number losses that pinpoint potential tumor suppressors

Mayumi Nishimura, Kazuhiro Daino, Maki Fukuda, Ikuya Tanaka, Hitomi Moriyama, Kaye Showler, Yukiko Nishimura, Masaru Takabatake, Toshiaki Kokubo, Atsuko Ishikawa, Kazumasa Inoue, Masahiro Fukushi, Shizuko Kakinuma, Tatsuhiko Imaoka, Yoshiya Shimada

published 13 Aug 2021

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A propagation-based seed-centric local community detection for multilayer environment: The case study of colon adenocarcinoma

Ehsan Pournoor, Zaynab Mousavian, Abbas Nowzari-Dalini, Ali Masoudi-Nejad

published 09 Aug 2021

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Incidence of malignant transformation in the oviductal fimbria in laying hens, a preclinical model of spontaneous ovarian cancer

Elizabeth A. Paris, Janice M. Bahr, Pincas Bitterman, Sanjib Basu, Jacques S. Abramowicz, Animesh Barua

published 27 Jul 2021

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Constitutive activation of NF-κB inducing kinase (NIK) in the mesenchymal lineage using Osterix (Sp7)- or Fibroblast-specific protein 1 (S100a4)-Cre drives spontaneous soft tissue sarcoma

Jennifer L. Davis, Roman Thaler, Linda Cox, Biancamaria Ricci, Heather M. Zannit, Fei Wan, Roberta Faccio, Amel Dudakovic, Andre J. van Wijnen, Deborah J. Veis

published 22 Jul 2021

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Autocrine signaling by receptor tyrosine kinases in urothelial carcinoma of the bladder

Young H. Lee, Molly M. Lee, Dinuka M. De Silva, Arpita Roy, Cara E. Wright, Tiffany K. Wong, Rene Costello, Oluwole Olaku, Robert L. Grubb III, Piyush K. Agarwal, Andrea B. Apolo, Donald P. Bottaro

published 22 Jul 2021

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SUMO conjugation susceptibility of Akt/protein kinase B affects the expression of the pluripotency transcription factor Nanog in embryonic stem cells

Marcos Francia, Martin Stortz, Camila Vazquez Echegaray, Camila Oses, Paula Verneri, María Victoria Petrone, Ayelen Toro, Ariel Waisman, Santiago Miriuka, María Soledad Cosentino, Valeria Levi, Alejandra Guberman

published 09 Jul 2021

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Sonlicromanol’s active metabolite KH176m normalizes prostate cancer stem cell mPGES-1 overexpression and inhibits cancer spheroid growth

Xiaolan Jiang, Herma Renkema, Jan Smeitink, Julien Beyrath

published 09 Jul 2021

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Immunoglobulin gene rearrangement in Koreans with multiple myeloma: Clonality assessment and repertoire analysis using next-generation sequencing

Miyoung Kim, Kibum Jeon, Kasey Hutt, Alyssa M. Zlotnicki, Hyo Jung Kim, Jiwon Lee, Han-Sung Kim, Hee Jung Kang, Young Kyung Lee

published 24 Jun 2021

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