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Carcinogenesis

STAG2 mutations in the normal colon induce upregulation of oncogenic pathways in neighbouring wildtype cells

Wei Ni Yew, Christopher James Dean, Dedrick Kok Hong Chan

published 15 Oct 2025

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The role of lncRNA SNHG15 in UV-induced DNA damage repair

Xin Zhang, Jiahui Lin, Zixuan Fan, Sai Zhang, Meiqi Yang, Tingting Zhu, Qing Lu, Yuming Wang

published 09 Oct 2025

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Frizzled 7 drives amplification of cancer stem-cell subpopulations and the aggressiveness and poor differentiation of human hepatocellular carcinoma

Anaïs Lopez, Alexia Paturel, Nadim Fares, Floriane Pez, Guanxiong Wang, Patricia Gifu, Lydie Lefrançois, Jihed Chouaref, Pierre Saintigny, Janick Selves, Jean-Marie Peron, Michel Rivoire, Philippe Merle, Claude Caron de Fromentel

published 07 Oct 2025

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Role of c-Myc activating the transcription of PD-L1 in immune escape during benzene-induced malignant transformation of human lymphoblasts

Qihao Huang, Biyan Ye, Zhongming Ye, Shuyun Huang, Jiancheng Xue, Fengzhen Cui, Tikeng Jiang, Lei Sun, Yutao Zeng, Shaoying Wang, Yuting Chen, Huanwen Tang

published 12 Sep 2025

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Integrative network toxicology and molecular docking reveal 4-Nonylphenol’s multifaceted mechanisms in breast cancer pathogenesis

Congli Jia, Fu Yang

published 09 Sep 2025

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Sex-dependent effects of a gestational ketogenic diet on offspring birth and lifespan

Sarah M. Zala, Renata Santos, Eva Strasser, Alice Schadde, Sarah Kugler, Verena Strauss, Anna Kübber-Heiss, Diana Zala

published 17 Jul 2025

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The impact of mutations on TP53 protein and MicroRNA expression in HNSCC: Novel insights for diagnostic and therapeutic strategies

Ashraf Attia Mahmoud, Mohd Firdaus Raih, Edison Eukun Sage, Qurashi M. Ali, Omnia H. Suliman, Sabah A. E. Ibrahim, Osama Mohamed, Samar Abdelrazeg, Sofia B. Mohamed

published 07 May 2025

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Identification and functional analysis of five hub lncRNAs associated with oncogenesis of Hepatocellular Carcinoma

Zhaomin Deng, Lu Pu, Yongxin Ma, Hao Jiang

published 30 Apr 2025

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Impact of developmental state, p53 status, and interferon signaling on glioblastoma cell response to radiation and temozolomide treatment

Artem Berezovsky, Oluwademilade Nuga, Indrani Datta, Kimberly Bergman, Thais Sabedot, Katherine Gurdziel, Susan Irtenkauf, Laura Hasselbach, Yuling Meng, Claudius Mueller, Emanuel F. . Petricoin III, Stephen Brown, Neeraja Purandare, Sidhesh Aras, Tom Mikkelsen, Laila Poisson, Houtan Noushmehr, Douglas Ruden, Ana C. deCarvalho

published 07 Feb 2025

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IRX-related homeobox gene MKX is a novel oncogene in acute myeloid leukemia

Stefan Nagel, Corinna Meyer, Claudia Pommerenke

published 17 Dec 2024

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Pan-cancer analysis of B3GNT5 with potential implications for cancer immunotherapy and cancer stem cell stemness

Feng Peng, Yechen Feng, Shuo Yu, Ruizhi He, Hebin Wang, Yu Xie, Renyi Qin

published 13 Dec 2024

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LincROR promotes tumor growth of colorectal cancer through the miR-145/WNT2B/WNT10A/Wnt/β-catenin regulatory axis

Li-Qiang Deng, Shi-Ying Li, Tian Xie, Wei-Qiang Zeng, Yu-Yan Wang, Chuan-Jian Shi, Zhang Jin-Fang

published 15 Nov 2024

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Unlocking vinpocetine’s oncostatic potential in early-stage hepatocellular carcinoma: A new approach to oncogenic modulation by a nootropic drug

Osama A. Mohammed, Mahmoud E. Youssef, Rabab S. Hamad, Mustafa Ahmed Abdel-Reheim, Lobna A. Saleh, Mohannad Mohammad S. Alamri, Muffarah Hamid Alharthi, Jaber Alfaifi, Masoud I. E. Adam, Ali M. S. Eleragi, Ahmed Senbel, Alshaimaa A. Farrag, Assad Ali Rezigalla, Hend S. El-wakeel, Mohammed A. Attia, Hussein M. El-Husseiny, Tohada M. AL-Noshokaty, Ahmed S. Doghish, Ahmed Gaafar Ahmed Gaafar, Sameh Saber

published 31 Oct 2024

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