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Bovine spongiform encephalopathy

Development of a sensitive real-time quaking-induced conversion (RT-QuIC) assay for application in prion-infected blood

Charlotte M. Thomas, M. Khalid F. Salamat, Christopher de Wolf, Sandra McCutcheon, A. Richard Alejo Blanco, Jean C. Manson, Nora Hunter, E. Fiona Houston

published 02 Nov 2023

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Molecular characterisation of atypical BSE prions by mass spectrometry and changes following transmission to sheep and transgenic mouse models

Adriana Gielbert, Jemma K. Thorne, Jane M. Plater, Leigh Thorne, Peter C. Griffiths, Marion M. Simmons, Claire A. Cassar

published 08 Nov 2018

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Detection of PrP^res in peripheral tissue in pigs with clinical disease induced by intracerebral challenge with sheep-passaged bovine spongiform encephalopathy agent

Carlos Hedman, Alicia Otero, Jean-Yves Douet, Caroline Lacroux, Séverine Lugan, Hicham Filali, Fabien Corbière, Naima Aron, Juan José Badiola, Olivier Andréoletti, Rosa Bolea

published 05 Jul 2018

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Clinical, pathological, and molecular features of classical and L-type atypical-BSE in goats

Elena Vallino Costassa, Antonio D’Angelo, Maria Mazza, Daniela Meloni, Elisa Baioni, Cristiana Maurella, Silvia Colussi, Nicola Martinelli, Monica Lo Faro, Elena Berrone, Alessandra Favole, Paola Crociara, Silvia Grifoni, Marina Gallo, Guerino Lombardi, Barbara Iulini, Cristina Casalone, Cristiano Corona

published 24 May 2018

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Detection and partial discrimination of atypical and classical bovine spongiform encephalopathies in cattle and primates using real-time quaking-induced conversion assay

Etienne Levavasseur, Anne-Gaëlle Biacabe, Emmanuel Comoy, Audrey Culeux, Katarina Grznarova, Nicolas Privat, Steve Simoneau, Benoit Flan, Véronique Sazdovitch, Danielle Seilhean, Thierry Baron, Stéphane Haïk

published 23 Feb 2017

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Use of bovine recombinant prion protein and real-time quaking-induced conversion to detect cattle transmissible mink encephalopathy prions and discriminate classical and atypical L- and H-Type bovine spongiform encephalopathy

Soyoun Hwang, Justin J. Greenlee, Eric M. Nicholson

published 22 Feb 2017

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Whole Blood Gene Expression Profiling in Preclinical and Clinical Cattle Infected with Atypical Bovine Spongiform Encephalopathy

Elena Xerxa, Maura Barbisin, Maria Novella Chieppa, Helena Krmac, Elena Vallino Costassa, Paolo Vatta, Marion Simmons, Maria Caramelli, Cristina Casalone, Cristiano Corona, Giuseppe Legname

published 13 Apr 2016

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Minimum Effective Dose of Cattle and Sheep BSE for Oral Sheep Infection

Gillian McGovern, Stuart Martin, Martin Jeffrey, Glenda Dexter, Steve A. C. Hawkins, Sue J. Bellworthy, Lisa Thurston, Lynne Algar, Lorenzo González

published 11 Mar 2016

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Weighting of Criteria for Disease Prioritization Using Conjoint Analysis and Based on Health Professional and Student Opinion

Nadine Stebler, Gertraud Schuepbach-Regula, Peter Braam, Laura Cristina Falzon

published 11 Mar 2016

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Subcritical Water Hydrolysis Effectively Reduces the In Vitro Seeding Activity of PrP^Sc but Fails to Inactivate the Infectivity of Bovine Spongiform Encephalopathy Prions

Yuichi Murayama, Miyako Yoshioka, Hiroyuki Okada, Eri Takata, Kentaro Masujin, Yoshifumi Iwamaru, Noriko Shimozaki, Tomoaki Yamamura, Takashi Yokoyama, Shirou Mohri, Yuji Tsutsumi

published 16 Dec 2015

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Comparative Susceptibility of Sheep of Different Origins, Breeds and PRNP Genotypes to Challenge with Bovine Spongiform Encephalopathy and Scrapie

Fiona Houston, Wilfred Goldmann, James Foster, Lorenzo González, Martin Jeffrey, Nora Hunter

published 20 Nov 2015

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Transmissibility of H-Type Bovine Spongiform Encephalopathy to Hamster PrP Transgenic Mice

Hiroyuki Okada, Kentaro Masujin, Kohtaro Miyazawa, Takashi Yokoyama

published 14 Oct 2015

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A Naturally Occurring Bovine Tauopathy Is Geographically Widespread in the UK

Martin Jeffrey, Pedro Piccardo, Diane L. Ritchie, James W. Ironside, Alison J. E. Green, Gillian McGovern

published 19 Jun 2015

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