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Bioinformatics

Fine-Tuning Enhancer Models to Predict Transcriptional Targets across Multiple Genomes

Stein Aerts, Jacques van Helden, Olivier Sand, Bassem A. Hassan

Identification and Classification of Hubs in Brain Networks

Olaf Sporns, Christopher J. Honey, Rolf Kötter

Nullomers: Really a Matter of Natural Selection?

Claudia Acquisti, George Poste, David Curtiss, Sudhir Kumar

Conservation, Variability and the Modeling of Active Protein Kinases

James D. R. Knight, Bin Qian, David Baker, Rashmi Kothary

SLiMFinder: A Probabilistic Method for Identifying Over-Represented, Convergently Evolved, Short Linear Motifs in Proteins

Richard J. Edwards, Norman E. Davey, Denis C. Shields

Complete Genomic Characterization of a Pathogenic A.II Strain of Francisella tularensis Subspecies tularensis

Stephen M. Beckstrom-Sternberg, Raymond K. Auerbach, [ ... ], Paul S. Keim

Mammalian MicroRNA Prediction through a Support Vector Machine Model of Sequence and Structure

Ying Sheng, Pär G. Engström, Boris Lenhard

Early Evolution of Ionotropic GABA Receptors and Selective Regimes Acting on the Mammalian-Specific Theta and Epsilon Subunits

Christopher J. Martyniuk, Stéphane Aris-Brosou, [ ... ], Vance L. Trudeau

Structural and Functional Analyses of Five Conserved Positively Charged Residues in the L1 and N-Terminal DNA Binding Motifs of Archaeal RadA Protein

Li-Tzu Chen, Tzu-Ping Ko, [ ... ], Ting-Fang Wang

Wide-Scale Analysis of Human Functional Transcription Factor Binding Reveals a Strong Bias towards the Transcription Start Site

Yuval Tabach, Ran Brosh, [ ... ], Eytan Domany

Contribution of Exogenous Genetic Elements to the Group A Streptococcus Metagenome

Stephen B. Beres, James M. Musser

Simple Sequence Repeats Provide a Substrate for Phenotypic Variation in the Neurospora crassa Circadian Clock

Todd P. Michael, Sohyun Park, [ ... ], Kwangwon Lee

Phylogenomics Reshuffles the Eukaryotic Supergroups

Fabien Burki, Kamran Shalchian-Tabrizi, [ ... ], Jan Pawlowski

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