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Bioinformatics

Predicting the Functional Effect of Amino Acid Substitutions and Indels

Yongwook Choi, Gregory E. Sims, [ ... ], Agnes P. Chan

DNA Barcoding the Native Flowering Plants and Conifers of Wales

Natasha de Vere, Tim C. G. Rich, [ ... ], Mike J. Wilkinson

Pilon: An Integrated Tool for Comprehensive Microbial Variant Detection and Genome Assembly Improvement

Bruce J. Walker, Thomas Abeel, [ ... ], Ashlee M. Earl

progressiveMauve: Multiple Genome Alignment with Gene Gain, Loss and Rearrangement

Aaron E. Darling, Bob Mau, Nicole T. Perna

A Two-Locus Global DNA Barcode for Land Plants: The Coding rbcL Gene Complements the Non-Coding trnH-psbA Spacer Region

W. John Kress, David L. Erickson

Circular RNAs Are the Predominant Transcript Isoform from Hundreds of Human Genes in Diverse Cell Types

Julia Salzman, Charles Gawad, [ ... ], Patrick O. Brown

Reducing the Effects of PCR Amplification and Sequencing Artifacts on 16S rRNA-Based Studies

Patrick D. Schloss, Dirk Gevers, Sarah L. Westcott

High-Coverage ITS Primers for the DNA-Based Identification of Ascomycetes and Basidiomycetes in Environmental Samples

Hirokazu Toju, Akifumi S. Tanabe, Satoshi Yamamoto, Hirotoshi Sato

Comparing bioinformatic pipelines for microbial 16S rRNA amplicon sequencing

Andrei Prodan, Valentina Tremaroli, [ ... ], Evgeni Levin

Stalking the Fourth Domain in Metagenomic Data: Searching for, Discovering, and Interpreting Novel, Deep Branches in Marker Gene Phylogenetic Trees

Dongying Wu, Martin Wu, [ ... ], Jonathan A. Eisen

Searching for Tissue-Specific Expression Pattern-Linked Nucleotides of UGT1A Isoforms

Wei Zhang, Wanqing Liu, Federico Innocenti, Mark J. Ratain

Characterization of the 18S rRNA Gene for Designing Universal Eukaryote Specific Primers

Kenan Hadziavdic, Katrine Lekang, [ ... ], Christofer Troedsson

Strengths and Limitations of 16S rRNA Gene Amplicon Sequencing in Revealing Temporal Microbial Community Dynamics

Rachel Poretsky, Luis M. Rodriguez-R, [ ... ], Konstantinos T. Konstantinidis

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