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Bioengineering

Small Molecule Inhibitors of the LEDGF Site of Human Immunodeficiency Virus Integrase Identified by Fragment Screening and Structure Based Design

Thomas S. Peat, David I. Rhodes, [ ... ], John J. Deadman

Efficient Production of Pyruvate from DL-Lactate by the Lactate-Utilizing Strain Pseudomonas stutzeri SDM

Chao Gao, Jianhua Qiu, Cuiqing Ma, Ping Xu

Mouse Models for Methylmalonic Aciduria

Heidi L. Peters, James J. Pitt, [ ... ], Nicole E. Buck

In Vitro Assays Using Primary Embryonic Mouse Lymphatic Endothelial Cells Uncover Key Roles for FGFR1 Signalling in Lymphangiogenesis

Jan Kazenwadel, Genevieve A. Secker, Kelly L. Betterman, Natasha L. Harvey

Peptide YY Regulates Bone Remodeling in Mice: A Link between Gut and Skeletal Biology

Iris P. L. Wong, Frank Driessler, [ ... ], Paul A. Baldock

Acid Sensing Ion Channel 1 in Lateral Hypothalamus Contributes to Breathing Control

Nana Song, Guihong Zhang, [ ... ], Linlin Shen

Cardioprotection of Controlled and Cardiac-Specific Over-Expression of A_2A-Adenosine Receptor in the Pressure Overload

Eman A. Hamad, Weizhong Zhu, [ ... ], Arthur M. Feldman

POWRS: Position-Sensitive Motif Discovery

Ian W. Davis, Christopher Benninger, Philip N. Benfey, Tedd Elich

Hsp72 Overexpression Accelerates the Recovery from Caerulein-Induced Pancreatitis

Mariia Lunova, Eugen Zizer, [ ... ], Pavel Strnad

GIP-Overexpressing Mice Demonstrate Reduced Diet-Induced Obesity and Steatosis, and Improved Glucose Homeostasis

Su-Jin Kim, Cuilan Nian, [ ... ], Christopher H. S. McIntosh

Gq/11-Mediated Signaling and Hypertrophy in Mice with Cardiac-Specific Transgenic Expression of Regulator of G-Protein Signaling 2

Cindy Park-Windhol, Peng Zhang, [ ... ], Ulrike Mende

A Pro-Cathepsin L Mutant Is a Luminal Substrate for Endoplasmic-Reticulum-Associated Degradation in C. elegans

Mark T. Miedel, Nathan J. Graf, [ ... ], Cliff J. Luke

Probing of Exosites Leads to Novel Inhibitor Scaffolds of HCV NS3/4A Proteinase

Sergey A. Shiryaev, Anton V. Cheltsov, Alex Y. Strongin

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