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Binding analysis

Single Cycle Structure-Based Humanization of an Anti-Nerve Growth Factor Therapeutic Antibody

Sonia Covaceuszach, Sara Marinelli, Ivet Krastanova, Gabriele Ugolini, Flaminia Pavone, Doriano Lamba, Antonino Cattaneo

published 05 Mar 2012

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Aptamers as a Sensitive Tool to Detect Subtle Modifications in Therapeutic Proteins

Ran Zichel, Wanida Chearwae, Gouri Shankar Pandey, Basil Golding, Zuben E. Sauna

published 27 Feb 2012

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Molecular Targets for 17α-Ethynyl-5-Androstene-3β,7β,17β-Triol, an Anti-Inflammatory Agent Derived from the Human Metabolome

Christopher L. Reading, James M. Frincke, Steven K. White

published 24 Feb 2012

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Structure Based Design and Synthesis of Peptide Inhibitor of Human LOX-12: In Vitro and In Vivo Analysis of a Novel Therapeutic Agent for Breast Cancer

Abhay kumar Singh, Ratnakar Singh, Farhat Naz, Shyam Singh Chauhan, Amit Dinda, Abhay Anand Shukla, Kamaldeep Gill, Vaishali Kapoor, Sharmistha Dey

published 23 Feb 2012

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Contribution of Transcription Factor Binding Site Motif Variants to Condition-Specific Gene Expression Patterns in Budding Yeast

Joshua S. Rest, Kevin Bullaughey, Geoffrey P. Morris, Wen-Hsiung Li

published 23 Feb 2012

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Spleen Tyrosine Kinase Regulates AP-1 Dependent Transcriptional Response to Minimally Oxidized LDL

Soo-Ho Choi, Philipp Wiesner, Felicidad Almazan, Jungsu Kim, Yury I. Miller

published 22 Feb 2012

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Systematic Evaluation of the Metabolic to Mitogenic Potency Ratio for B10-Substituted Insulin Analogues

Tine Glendorf, Louise Knudsen, Carsten E. Stidsen, Bo F. Hansen, Anne Charlotte Hegelund, Anders R. Sørensen, Erica Nishimura, Thomas Kjeldsen

published 22 Feb 2012

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Differential Adhesive Properties of Sequestered Asexual and Sexual Stages of Plasmodium falciparum on Human Endothelial Cells Are Tissue Independent

Francesco Silvestrini, Marta Tibúrcio, Lucia Bertuccini, Pietro Alano

published 21 Feb 2012

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Toward Low-Cost Affinity Reagents: Lyophilized Yeast-scFv Probes Specific for Pathogen Antigens

Sean A. Gray, Kris M. Weigel, Ibne K. M. Ali, Annie A. Lakey, Jeremy Capalungan, Gonzalo J. Domingo, Gerard A. Cangelosi

published 20 Feb 2012

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Ghrelin Indirectly Activates Hypophysiotropic CRF Neurons in Rodents

Agustina Cabral, Olga Suescun, Jeffrey M. Zigman, Mario Perello

published 20 Feb 2012

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Structure-Based Rational Design of a Toll-like Receptor 4 (TLR4) Decoy Receptor with High Binding Affinity for a Target Protein

Jieun Han, Hyun Jung Kim, Sang-Chul Lee, Seungpyo Hong, Keunwan Park, Young Ho Jeon, Dongsup Kim, Hae-Kap Cheong, Hak-Sung Kim

published 17 Feb 2012

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Novel Covalently Linked Insulin Dimer Engineered to Investigate the Function of Insulin Dimerization

Tine N. Vinther, Mathias Norrman, Holger M. Strauss, Kasper Huus, Morten Schlein, Thomas Å. Pedersen, Thomas Kjeldsen, Knud J. Jensen, František Hubálek

published 17 Feb 2012

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Probing High Affinity Sequences of DNA Aptamer against VEGF₁₆₅

Harleen Kaur, Lin-Yue Lanry Yung

published 16 Feb 2012

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