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Binding analysis

In silico elucidation of potential drug targets against oxygenase domain of Human eNOS Dysfunction

Abbeha Malik, Muhammad Nasir Iqbal, Sidrah Ashraf, Muhammad Saleem Khan, Samar Shahzadi, Muhammad Farhan Shafique, Zureesha Sajid, Muhammad Sajid, Sheikh Arslan Sehgal

published 26 Apr 2023

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Artemisinin suppresses aerobic glycolysis in thyroid cancer cells by downregulating HIF-1a, which is increased by the XIST/miR-93/HIF-1a pathway

Fei Yang, Jie Zhang, Zhijun Zhao, Yan Liu, Zhen Zhao, Kai Fu, Baokun Li, Jing Jin

published 10 Apr 2023

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Characterization of methylation profiles in spontaneous preterm birth placental villous tissue

Heather M. Brockway, Samantha L. Wilson, Suhas G. Kallapur, Catalin S. Buhimschi, Louis J. Muglia, Helen N. Jones

published 23 Mar 2023

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Direct selection of functional fluorescent-protein antibody fusions by yeast display

Nileena Velappan, Fortunato Ferrara, Sara D’Angelo, Devin Close, Leslie Naranjo, Madeline R. Bolding, Sarah C. Mozden, Camille B. Troup, Donna K. McCullough, Analyssa Gomez, Marijo Kedge, Andrew R. M. Bradbury

published 24 Feb 2023

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Effect of acetic acid inactivation of SARS-CoV-2

Narayanappa Amruta, Nicholas J. Maness, Timothy E. Gressett, Yoshihiro Tsuchiya, Mikiya Kishi, Gregory Bix

published 08 Feb 2023

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Studies with neutralizing antibodies suggest CXCL8-mediated neutrophil activation is independent of C-C motif chemokine receptor-like 2 (CCRL2) ligand binding function

Zhenwei Su, Jonathan Brooks, Jeffrey Pelker, Tatyana Andreyeva, Hanna Sobon, Roger Gifford, Matthew Powers, Jing Wang, Corey Dower, Martin Hegen, Dean Messing, Alfredo Darmanin Sheehan, Joseph J. Brennan

published 20 Jan 2023

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SHP-1 tyrosine phosphatase binding to c-Src kinase phosphor-dependent conformations: A comparative structural framework

Mehreen Gul, Ahmad Navid, Muhammad Fakhar, Sajid Rashid

published 13 Jan 2023

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Molecular modelling of the HCMV IL-10 protein isoforms and analysis of their interaction with the human IL-10 receptor

Simone Queiroz Pantaleão, Lívia de Moraes Bomediano Camillo, Tainan Cerqueira Neves, Isabela de Godoy Menezes, Lucas Matheus Stangherlin, Helena Beatriz de Carvalho Ruthner Batista, Emma Poole, Michael Nevels, Eric Alisson Philot, Ana Ligia Scott, Maria Cristina Carlan da Silva

published 28 Nov 2022

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Vasoactive intestinal peptide and cystic fibrosis transmembrane conductance regulator contribute to the transepithelial calcium transport across intestinal epithelium-like Caco-2 monolayer

Mayuree Rodrat, Kannikar Wongdee, Jarinthorn Teerapornpuntakit, Jirawan Thongbunchoo, Duangrudee Tanramluk, Ratchaneevan Aeimlapa, Nithipak Thammayon, Natchayaporn Thonapan, Pathnaree Wattano, Narattaphol Charoenphandhu

published 18 Nov 2022

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Molecular dynamics study on the strengthening behavior of Delta and Omicron SARS-CoV-2 spike RBD improved receptor-binding affinity

Kanchanok Kodchakorn, Prachya Kongtawelert

published 17 Nov 2022

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ICAN: Interpretable cross-attention network for identifying drug and target protein interactions

Hiroyuki Kurata, Sho Tsukiyama

published 24 Oct 2022

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A microfluidics-based method for isolation and visualization of cells based on receptor-ligand interactions

Long Dao, Qingnan Zhao, Jiemiao Hu, Xueqing Xia, Qing Yang, Shulin Li

published 06 Oct 2022

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Mutations of tyrosine 467 in the human norepinephrine transporter attenuate HIV-1 Tat-induced inhibition of dopamine transport while retaining physiological function

Matthew J. Strauss, Katherine D. Porter, Pamela M. Quizon, Sarah E. Davis, Steven Lin, Yaxia Yuan, Gustavo A. Martinez-Muniz, Wei-Lun Sun, Chang-Guo Zhan, Jun Zhu

published 28 Sep 2022

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