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Binding analysis

A Dual Polybasic Motif Determines Phosphoinositide Binding and Regulation in the P2X Channel Family

Louis-Philippe Bernier, Dominique Blais, Éric Boué-Grabot, Philippe Séguéla

published 11 Jul 2012

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Calcium Binding Promotes Prion Protein Fragment 90–231 Conformational Change toward a Membrane Destabilizing and Cytotoxic Structure

Sacha Sorrentino, Tonino Bucciarelli, Alessandro Corsaro, Alessio Tosatto, Stefano Thellung, Valentina Villa, M. Eugenia Schininà, Bruno Maras, Roberta Galeno, Luca Scotti, Francesco Creati, Alessandro Marrone, Nazzareno Re, Antonio Aceto, Tullio Florio, Michele Mazzanti

published 11 Jul 2012

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Probing Cocaine-Antibody Interactions in Buffer and Human Serum

Muthu Ramakrishnan, Fernando Alves De Melo, Berma M. Kinsey, John E. Ladbury, Thomas R. Kosten, Frank M. Orson

published 10 Jul 2012

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Membrane Fusion Proteins of Type I Secretion System and Tripartite Efflux Pumps Share a Binding Motif for TolC in Gram-Negative Bacteria

Minho Lee, So-Young Jun, Bo-Young Yoon, Saemee Song, Kangseok Lee, Nam-Chul Ha

published 06 Jul 2012

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The Hinge Region of Human Thyroid-Stimulating Hormone (TSH) Receptor Operates as a Tunable Switch between Hormone Binding and Receptor Activation

Ritankar Majumdar, Rajan R. Dighe

published 06 Jul 2012

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Fluorophore Labeled Kinase Detects Ligands That Bind within the MAPK Insert of p38α Kinase

Matthäus Getlik, Jeffrey R. Simard, Martin Termathe, Christian Grütter, Matthias Rabiller, Willem A. L. van Otterlo, Daniel Rauh

published 02 Jul 2012

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Dual Hypocretin Receptor Antagonism Is More Effective for Sleep Promotion than Antagonism of Either Receptor Alone

Stephen R. Morairty, Florent G. Revel, Pari Malherbe, Jean-Luc Moreau, Daniel Valladao, Joseph G. Wettstein, Thomas S. Kilduff, Edilio Borroni

published 02 Jul 2012

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Minichromosome Maintenance 2 Bound with Retroviral Gp70 Is Localized to Cytoplasm and Enhances DNA-Damage-Induced Apoptosis

Shinya Abe, Morito Kurata, Shiho Suzuki, Kouhei Yamamoto, Ken-ichi Aisaki, Jun Kanno, Masanobu Kitagawa

published 29 Jun 2012

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Structural Modeling and DNA Binding Autoinhibition Analysis of Ergp55, a Critical Transcription Factor in Prostate Cancer

Shanti P. Gangwar, Sharmistha Dey, Ajay K. Saxena

published 28 Jun 2012

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A Transplantable Phosphorylation Probe for Direct Assessment of G Protein-Coupled Receptor Activation

Andrea Kliewer, Anika Mann, Aline Petrich, Florian Pöll, Stefan Schulz

published 26 Jun 2012

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Detection of Simultaneous Group Effects in MicroRNA Expression and Related Target Gene Sets

Stephan Artmann, Klaus Jung, Annalen Bleckmann, Tim Beißbarth

published 19 Jun 2012

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A Two-Step Target Binding and Selectivity Support Vector Machines Approach for Virtual Screening of Dopamine Receptor Subtype-Selective Ligands

Jingxian Zhang, Bucong Han, Xiaona Wei, Chunyan Tan, Yuzong Chen, Yuyang Jiang

published 15 Jun 2012

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Leukemia Gene Atlas – A Public Platform for Integrative Exploration of Genome-Wide Molecular Data

Katja Hebestreit, Sören Gröttrup, Daniel Emden, Jannis Veerkamp, Christian Ruckert, Hans-Ulrich Klein, Carsten Müller-Tidow, Martin Dugas

published 14 Jun 2012

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