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Binding analysis

A Dual Polybasic Motif Determines Phosphoinositide Binding and Regulation in the P2X Channel Family

Louis-Philippe Bernier, Dominique Blais, Éric Boué-Grabot, Philippe Séguéla

Calcium Binding Promotes Prion Protein Fragment 90–231 Conformational Change toward a Membrane Destabilizing and Cytotoxic Structure

Sacha Sorrentino, Tonino Bucciarelli, [ ... ], Michele Mazzanti

Probing Cocaine-Antibody Interactions in Buffer and Human Serum

Muthu Ramakrishnan, Fernando Alves De Melo, [ ... ], Frank M. Orson

Membrane Fusion Proteins of Type I Secretion System and Tripartite Efflux Pumps Share a Binding Motif for TolC in Gram-Negative Bacteria

Minho Lee, So-Young Jun, [ ... ], Nam-Chul Ha

The Hinge Region of Human Thyroid-Stimulating Hormone (TSH) Receptor Operates as a Tunable Switch between Hormone Binding and Receptor Activation

Ritankar Majumdar, Rajan R. Dighe

Fluorophore Labeled Kinase Detects Ligands That Bind within the MAPK Insert of p38α Kinase

Matthäus Getlik, Jeffrey R. Simard, [ ... ], Daniel Rauh

Dual Hypocretin Receptor Antagonism Is More Effective for Sleep Promotion than Antagonism of Either Receptor Alone

Stephen R. Morairty, Florent G. Revel, [ ... ], Edilio Borroni

Minichromosome Maintenance 2 Bound with Retroviral Gp70 Is Localized to Cytoplasm and Enhances DNA-Damage-Induced Apoptosis

Shinya Abe, Morito Kurata, [ ... ], Masanobu Kitagawa

Structural Modeling and DNA Binding Autoinhibition Analysis of Ergp55, a Critical Transcription Factor in Prostate Cancer

Shanti P. Gangwar, Sharmistha Dey, Ajay K. Saxena

A Transplantable Phosphorylation Probe for Direct Assessment of G Protein-Coupled Receptor Activation

Andrea Kliewer, Anika Mann, [ ... ], Stefan Schulz

Detection of Simultaneous Group Effects in MicroRNA Expression and Related Target Gene Sets

Stephan Artmann, Klaus Jung, Annalen Bleckmann, Tim Beißbarth

A Two-Step Target Binding and Selectivity Support Vector Machines Approach for Virtual Screening of Dopamine Receptor Subtype-Selective Ligands

Jingxian Zhang, Bucong Han, [ ... ], Yuyang Jiang

Leukemia Gene Atlas – A Public Platform for Integrative Exploration of Genome-Wide Molecular Data

Katja Hebestreit, Sören Gröttrup, [ ... ], Martin Dugas

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