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Binding analysis

Exploring the Chemical Space around 8-Mercaptoguanine as a Route to New Inhibitors of the Folate Biosynthesis Enzyme HPPK

Sandeep Chhabra, Nicholas Barlow, Olan Dolezal, Meghan K. Hattarki, Janet Newman, Thomas S. Peat, Bim Graham, James D. Swarbrick

published 02 Apr 2013

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Toll-Like Receptor 2 and Toll-Like Receptor 4-Dependent Activation of B Cells by a Polysaccharide from Marine Fungus Phoma herbarum YS4108

Xian Zhang, Ran Ding, Yan Zhou, Rui Zhu, Wei Liu, Lei Jin, Wenbing Yao, Xiangdong Gao

published 29 Mar 2013

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Up-Regulation of RACK1 by TGF-β1 Promotes Hepatic Fibrosis in Mice

Dongwei Jia, Fangfang Duan, Peike Peng, Linlin Sun, Xiaojuan Liu, Lan Wang, Weicheng Wu, Yuanyuan Ruan, Jianxin Gu

published 29 Mar 2013

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Haptoglobin Preferentially Binds β but Not α Subunits Cross-Linked Hemoglobin Tetramers with Minimal Effects on Ligand and Redox Reactions

Yiping Jia, Francine Wood, Paul W. Buehler, Abdu I. Alayash

published 29 Mar 2013

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Understanding the Specificity of Human Galectin-8C Domain Interactions with Its Glycan Ligands Based on Molecular Dynamics Simulations

Sonu Kumar, Martin Frank, Reinhard Schwartz-Albiez

published 29 Mar 2013

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A Bead Aggregation Assay for Detection of Low-Affinity Protein-Protein Interactions Reveals Interactions between N-Terminal Domains of Inositol 1,4,5-Trisphosphate Receptors

Alap P. Chavda, David L. Prole, Colin W. Taylor

published 26 Mar 2013

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Characterization of a Single-Chain Variable Fragment Recognizing a Linear Epitope of Aβ: A Biotechnical Tool for Studies on Alzheimer’s Disease?

Silke Dornieden, Andreas Müller-Schiffmann, Heinrich Sticht, Nan Jiang, Yeliz Cinar, Michael Wördehoff, Carsten Korth, Susanne Aileen Funke, Dieter Willbold

published 26 Mar 2013

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Structural and Dynamical Insights on HLA-DR2 Complexes That Confer Susceptibility to Multiple Sclerosis in Sardinia: A Molecular Dynamics Simulation Study

Amit Kumar, Eleonora Cocco, Luigi Atzori, Maria Giovanna Marrosu, Enrico Pieroni

published 26 Mar 2013

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PARP-1 and YY1 Are Important Novel Regulators of CXCL12 Gene Transcription in Rat Pancreatic Beta Cells

Jelena Marković, Nevena Grdović, Svetlana Dinić, Teodora Karan-Djurašević, Aleksandra Uskoković, Jelena Arambašić, Mirjana Mihailović, Sonja Pavlović, Goran Poznanović, Melita Vidaković

published 26 Mar 2013

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Preferential Binding of Hot Spot Mutant p53 Proteins to Supercoiled DNA In Vitro and in Cells

Marie Brázdová, Lucie Navrátilová, Vlastimil Tichý, Kateřina Němcová, Matej Lexa, Roman Hrstka, Petr Pečinka, Matej Adámik, Borivoj Vojtesek, Emil Paleček, Wolfgang Deppert, Miroslav Fojta

published 26 Mar 2013

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Expression and Pharmacology of Endogenous Ca_v Channels in SH-SY5Y Human Neuroblastoma Cells

Silmara R. Sousa, Irina Vetter, Lotten Ragnarsson, Richard J. Lewis

published 25 Mar 2013

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The Association of BAG6 with SGTA and Tail-Anchored Proteins

Pawel Leznicki, Quentin P. Roebuck, Lydia Wunderley, Anne Clancy, Ewelina M. Krysztofinska, Rivka L. Isaacson, Jim Warwicker, Blanche Schwappach, Stephen High

published 22 Mar 2013

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Rapid High-Level Production of Functional HIV Broadly Neutralizing Monoclonal Antibodies in Transient Plant Expression Systems

Yvonne Rosenberg, Markus Sack, David Montefiori, Donald Forthal, Lingjun Mao, Segundo Hernandez -Abanto, Lori Urban, Gary Landucci, Rainer Fischer, Xiaoming Jiang

published 22 Mar 2013

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