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Binding analysis

An in silico investigation on the binding site preference of PD-1 and PD-L1 for designing antibodies for targeted cancer therapy

Sarah Abdolmaleki, Mazdak Ganjalikhani hakemi, Mohamad Reza Ganjalikhany

published 25 Jul 2024

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Positive charges promote the recognition of proteins by the chaperone SlyD from Escherichia coli

Daniel Lindemeier, Wenke Graubner, Denise Mehner-Breitfeld, Miroslav Malešević, Thomas Brüser

published 25 Jun 2024

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Expression and purification of human neutrophil proteinase 3 from insect cells and characterization of ligand binding

Fahimeh Khorsand, Bengt Erik Haug, Inari Kursula, Nathalie Reuter, Ruth Brenk

published 25 Jun 2024

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A homogeneous time-resolved fluorescence screen to identify SIRT2 deacetylase and defatty-acylase inhibitors

Jie Yang, Joel Cassel, Brian C. Boyle, Daniel Oppong, Young-Hoon Ahn, Brian P. Weiser

published 24 Jun 2024

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Structural characterization of two nanobodies targeting the ligand-binding pocket of human Arc

José M. Godoy Muñoz, Lasse Neset, Sigurbjörn Markússon, Sarah Weber, Oda C. Krokengen, Aleksi Sutinen, Eleni Christakou, Andrea J. Lopez, Clive R. Bramham, Petri Kursula

published 29 Apr 2024

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Epigallocatechin gallate regulates the myeloid-specific transcription factor PU.1 in macrophages

Manjula Karpurapu, Kavita Kumari Kakarala, Sangwoon Chung, Yunjuan Nie, Amritendu Koley, Patrick Dougherty, John W. Christman

published 25 Apr 2024

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AviTrap: A novel solution to achieve complete biotinylation

Cheng Lu, Jack Bevers, Tulika Tyagi, Hao To, May Lin, Shu Ti, Gerry Nakamura, WeiYu Lin, Yongmei Chen, Yan Wu, Hong Li, Jiansheng Wu, Feng Wang

published 25 Apr 2024

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circTADA2A inhibited SLC38A1 expression and suppresses melanoma progression through the prevention of CNBP trans-activation

Longjun Zhang, Le Zhang, Chi Zhang, Sunan Shi, Zhilei Cao, Changliang Shao, Jie Li, Yingshun Yang, Xi Zhang, Jian Wang, Xiangyun Li

published 18 Apr 2024

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Chemical range recognized by the ligand-binding domain in a representative amino acid-sensing taste receptor, T1r2a/T1r3, from medaka fish

Hikaru Ishida, Norihisa Yasui, Atsuko Yamashita

published 22 Mar 2024

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Antibody desolvation with sodium chloride and acetonitrile generates bioactive protein nanoparticles

Levi Collin Nelemans, Vinicio Alejandro Melo, Matej Buzgo, Edwin Bremer, Aiva Simaite

published 14 Mar 2024

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Structural insights into the modulation Of SOD1 aggregation By a fungal metabolite Phialomustin-B: Therapeutic potential in ALS

Sruthi Unni, Padmini Kommu, Snehal Aouti, Yedukondalu Nalli, M. M. Srinivas Bharath, Asif Ali, Balasundaram Padmanabhan

published 06 Mar 2024

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Generation of epitope-specific hCG aptamers through a novel targeted selection approach

Lauren Ferreira, Shane Patrick Flanagan, Ronen Fogel, Janice Leigh Limson

published 23 Feb 2024

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Magnetic capture device for large volume sample analysis

Cheryl M. Armstrong, Joseph A. Capobianco, Joe Lee

published 09 Feb 2024

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