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Binding analysis

Comparing Binding Modes of Analogous Fragments Using NMR in Fragment-Based Drug Design: Application to PRDX5

Clémentine Aguirre, Tim ten Brink, Jean-François Guichou, Olivier Cala, Isabelle Krimm

published 15 Jul 2014

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Dissecting Virus Entry: Replication-Independent Analysis of Virus Binding, Internalization, and Penetration Using Minimal Complementation of β-Galactosidase

Christine Burkard, Louis-Marie Bloyet, Oliver Wicht, Frank J. van Kuppeveld, Peter J. M. Rottier, Cornelis A. M. de Haan, Berend Jan Bosch

published 15 Jul 2014

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An Animal Model with a Cardiomyocyte-Specific Deletion of Estrogen Receptor Alpha: Functional, Metabolic, and Differential Network Analysis

Sriram Devanathan, Timothy Whitehead, George G. Schweitzer, Nicole Fettig, Attila Kovacs, Kenneth S. Korach, Brian N. Finck, Kooresh I. Shoghi

published 07 Jul 2014

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Enantiospecific Effects of Ketoconazole on Aryl Hydrocarbon Receptor

Aneta Novotna, Martina Korhonova, Iveta Bartonkova, Anatoly A. Soshilov, Michael S. Denison, Katerina Bogdanova, Milan Kolar, Petr Bednar, Zdenek Dvorak

published 07 Jul 2014

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Anti-miRs Competitively Inhibit microRNAs in Argonaute Complexes

Daniel J. Hogan, Thomas M. Vincent, Sarah Fish, Eric G. Marcusson, Balkrishen Bhat, B. Nelson Chau, Dimitrios G. Zisoulis

published 03 Jul 2014

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Glycolipid Binding Preferences of Shiga Toxin Variants

Sayali S. Karve, Alison A. Weiss

published 01 Jul 2014

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Miz-1 Activates Gene Expression via a Novel Consensus DNA Binding Motif

Bonnie L. Barrilleaux, Dana Burow, Sarah H. Lockwood, Abigail Yu, David J. Segal, Paul S. Knoepfler

published 01 Jul 2014

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Insight into PreImplantation Factor (PIF*) Mechanism for Embryo Protection and Development: Target Oxidative Stress and Protein Misfolding (PDI and HSP) through Essential RIPK Binding Site

Eytan R. Barnea, David M. Lubman, Yan-Hui Liu, Victor Absalon-Medina, Soren Hayrabedyan, Krassimira Todorova, Robert O. Gilbert, Joy Guingab, Timothy J. Barder

published 01 Jul 2014

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A Characteristic Back Support Structure in the Bisphenol A-Binding Pocket in the Human Nuclear Receptor ERRγ

Xiaohui Liu, Ayami Matsushima, Miki Shimohigashi, Yasuyuki Shimohigashi

published 30 Jun 2014

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Soluble Phosphatidylserine Binds to Two Sites on Human Factor IXa in a Ca²⁺ Dependent Fashion to Specifically Regulate Structure and Activity

Rinku Majumder, Tilen Koklic, Tanusree Sengupta, Daud Cole, Rima Chattopadhyay, Subir Biswas, Dougald Monroe, Barry R. Lentz

published 30 Jun 2014

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DNA Aptamer Evolved by Cell-SELEX for Recognition of Prostate Cancer

Yuanyuan Wang, Yun Luo, Tao Bing, Zheng Chen, Minhua Lu, Nan Zhang, Dihua Shangguan, Xin Gao

published 23 Jun 2014

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BRCA1 Haploinsufficiency Leads to Altered Expression of Genes Involved in Cellular Proliferation and Development

Harriet E. Feilotter, Claire Michel, Paolo Uy, Lauren Bathurst, Scott Davey

published 20 Jun 2014

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Profiling Animal Toxicants by Automatically Mining Public Bioassay Data: A Big Data Approach for Computational Toxicology

Jun Zhang, Jui-Hua Hsieh, Hao Zhu

published 20 Jun 2014

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