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Binding analysis

The DNA Binding Property of PML/RARA but Not the Integrity of PML Nuclear Bodies Is Indispensable for Leukemic Transformation

Xi Liu, Hao Yuan, Laurent Peres, Saijuan Chen, Zhu Chen, Hugues de The, Jun Zhou, Jun Zhu

published 13 Aug 2014

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In Silico Analysis of Missense Mutations in LPAR6 Reveals Abnormal Phospholipid Signaling Pathway Leading to Hypotrichosis

Syed Irfan Raza, Dost Muhammad, Abid Jan, Raja Hussain Ali, Mubashir Hassan, Wasim Ahmad, Sajid Rashid

published 13 Aug 2014

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A Computational Approach to Evaluate the Androgenic Affinity of Iprodione, Procymidone, Vinclozolin and Their Metabolites

Corrado Lodovico Galli, Cristina Sensi, Amos Fumagalli, Chiara Parravicini, Marina Marinovich, Ivano Eberini

published 11 Aug 2014

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¹⁸F-Glutathione Conjugate as a PET Tracer for Imaging Tumors that Overexpress L-PGDS Enzyme

Ho-Lien Huang, Ying-Cheng Huang, Wei-Yuan Lee, Chun-Nan Yeh, Kun-Ju Lin, Chung-Shan Yu

published 11 Aug 2014

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Binding of HIV-1 gp41-Directed Neutralizing and Non-Neutralizing Fragment Antibody Binding Domain (Fab) and Single Chain Variable Fragment (ScFv) Antibodies to the Ectodomain of gp41 in the Pre-Hairpin and Six-Helix Bundle Conformations

John M. Louis, Annie Aniana, Katheryn Lohith, Jane M. Sayer, Julien Roche, Carole A. Bewley, G. Marius Clore

published 08 Aug 2014

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Improving the Anti-Toxin Abilities of the CMG2-Fc Fusion Protein with the Aid of Computational Design

Yongyi Xi, Xiaojie Wu, Lihua Gao, Yong Shao, Hui Peng, Hongxing Chen, Huipeng Chen, Xianwen Hu, Junjie Yue

published 07 Aug 2014

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MicroRNA-150 Predicts a Favorable Prognosis in Patients with Epithelial Ovarian Cancer, and Inhibits Cell Invasion and Metastasis by Suppressing Transcriptional Repressor ZEB1

Minfei Jin, Zujing Yang, Weiping Ye, Hongling Xu, Xiaolin Hua

published 04 Aug 2014

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Engineering of Bispecific Affinity Proteins with High Affinity for ERBB2 and Adaptable Binding to Albumin

Johan Nilvebrant, Mikael Åstrand, Maria Georgieva-Kotseva, Mattias Björnmalm, John Löfblom, Sophia Hober

published 04 Aug 2014

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Phage Orf Family Recombinases: Conservation of Activities and Involvement of the Central Channel in DNA Binding

Fiona A. Curtis, Ali D. Malay, Alexander J. Trotter, Lindsay A. Wilson, Michael M. H. Barradell-Black, Laura Y. Bowers, Patricia Reed, Christopher R. T. Hillyar, Robert P. Yeo, John M. Sanderson, Jonathan G. Heddle, Gary J. Sharples

published 01 Aug 2014

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Rational Modification of Estrogen Receptor by Combination of Computational and Experimental Analysis

Valentina Elisabetta Viviana Ferrero, Mattia Pedotti, Alessandro Chiadò, Luca Simonelli, Luigi Calzolai, Luca Varani, Teresa Lettieri

published 30 Jul 2014

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Molecular Dynamics of the Neuronal EF-Hand Ca²⁺-Sensor Caldendrin

Pasham Parameshwar Reddy, Vijeta Raghuram, Johannes Hradsky, Christina Spilker, Asima Chakraborty, Yogendra Sharma, Marina Mikhaylova, Michael R. Kreutz

published 24 Jul 2014

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Fusion of a Short Peptide that Binds Immunoglobulin G to a Recombinant Protein Substantially Increases Its Plasma Half-Life in Mice

Jonathan T. Sockolosky, Saul Kivimäe, Francis C. Szoka

published 24 Jul 2014

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Diabetic Osteopenia by Decreased β-Catenin Signaling Is Partly Induced by Epigenetic Derepression of sFRP-4 Gene

Kiyoshi Mori, Riko Kitazawa, Takeshi Kondo, Michiko Mori, Yasuhiro Hamada, Michiru Nishida, Yasuhiro Minami, Ryuma Haraguchi, Yutaka Takahashi, Sohei Kitazawa

published 18 Jul 2014

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