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Binding analysis

Constitutive Activity in an Ancestral Form of Abl Tyrosine Kinase

Saadat U. Aleem, Barbara P. Craddock, W. Todd Miller

published 19 Jun 2015

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Leukemia-Associated Mutations in Nucleophosmin Alter Recognition by CRM1: Molecular Basis of Aberrant Transport

Igor Arregi, Jorge Falces, Anne Olazabal-Herrero, Marián Alonso-Mariño, Stefka G. Taneva, José A. Rodríguez, María A. Urbaneja, Sonia Bañuelos

published 19 Jun 2015

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TAE226, a Bis-Anilino Pyrimidine Compound, Inhibits the EGFR-Mutant Kinase Including T790M Mutant to Show Anti-Tumor Effect on EGFR-Mutant Non-Small Cell Lung Cancer Cells

Hiroki Otani, Hiromasa Yamamoto, Munenori Takaoka, Masakiyo Sakaguchi, Junichi Soh, Masaru Jida, Tsuyoshi Ueno, Takafumi Kubo, Hiroaki Asano, Kazunori Tsukuda, Katsuyuki Kiura, Shinji Hatakeyama, Eiji Kawahara, Yoshio Naomoto, Shinichiro Miyoshi, Shinichi Toyooka

published 19 Jun 2015

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Ligand Recognition of the Major Birch Pollen Allergen Bet v 1 is Isoform Dependent

Christian Seutter von Loetzen, Thessa Jacob, Olivia Hartl-Spiegelhauer, Lothar Vogel, Dirk Schiller, Cornelia Spörlein-Güttler, Rainer Schobert, Stefan Vieths, Maximilian Johannes Hartl, Paul Rösch

published 04 Jun 2015

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Functional Coupling of Duplex Translocation to DNA Cleavage in a Type I Restriction Enzyme

Eva Csefalvay, Mikalai Lapkouski, Alena Guzanova, Ladislav Csefalvay, Tatsiana Baikova, Igor Shevelev, Vitali Bialevich, Katsiaryna Shamayeva, Pavel Janscak, Ivana Kuta Smatanova, Santosh Panjikar, Jannette Carey, Marie Weiserova, Rüdiger Ettrich

published 03 Jun 2015

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A Model for Aryl Hydrocarbon Receptor-Activated Gene Expression Shows Potency and Efficacy Changes and Predicts Squelching Due to Competition for Transcription Co-Activators

Ted W. Simon, Robert A. Budinsky, J. Craig Rowlands

published 03 Jun 2015

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Acyclovir Has Low but Detectable Influence on HLA-B*57:01 Specificity without Inducing Hypersensitivity

Imir G. Metushi, Amanda Wriston, Priyanka Banerjee, Bjoern Oliver Gohlke, A. Michelle English, Andrew Lucas, Carrie Moore, John Sidney, Soren Buus, David A. Ostrov, Simon Mallal, Elizabeth Phillips, Jeffrey Shabanowitz, Donald F. Hunt, Robert Preissner, Bjoern Peters

published 29 May 2015

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Validation of Normalizations, Scaling, and Photofading Corrections for FRAP Data Analysis

Minchul Kang, Manuel Andreani, Anne K. Kenworthy

published 27 May 2015

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Slow-Onset Inhibition of Mycobacterium tuberculosis InhA: Revealing Molecular Determinants of Residence Time by MD Simulations

Benjamin Merget, Christoph A. Sotriffer

published 21 May 2015

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A New Family of HEAT-Like Repeat Proteins Lacking a Critical Substrate Recognition Motif Present in Related DNA Glycosylases

Elwood A. Mullins, Rongxin Shi, Lyle A. Kotsch, Brandt F. Eichman

published 15 May 2015

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Transcriptome Sequencing of Two Phenotypic Mosaic Eucalyptus Trees Reveals Large Scale Transcriptome Re-Modelling

Amanda Padovan, Hardip R. Patel, Aaron Chuah, Gavin A. Huttley, Sandra T. Krause, Jörg Degenhardt, William J. Foley, Carsten Külheim

published 15 May 2015

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Expression of GITR Enhances Multiple Myeloma Cell Sensitivity to Bortezomib

Yinghao Zhao, Kun Zhang, Guangquan Li, Xingyi Zhang, Donglei Shi

published 14 May 2015

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Cullin 3 Recognition Is Not a Universal Property among KCTD Proteins

Giovanni Smaldone, Luciano Pirone, Nicole Balasco, Sonia Di Gaetano, Emilia Maria Pedone, Luigi Vitagliano

published 14 May 2015

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