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Binding analysis

Functional Stability of the Human Kappa Opioid Receptor Reconstituted in Nanodiscs Revealed by a Time-Resolved Scintillation Proximity Assay

Randi Westh Hansen, Xiaole Wang, Agnieszka Golab, Olivier Bornert, Christine Oswald, Renaud Wagner, Karen Laurence Martinez

published 01 Apr 2016

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A Surfactant-Induced Functional Modulation of a Global Virulence Regulator from Staphylococcus aureus

Sukhendu Mandal, Avisek Mahapa, Anindya Biswas, Biswanath Jana, Soumitra Polley, Keya Sau, Subrata Sau

published 18 Mar 2016

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Profound Effects of Aggregatibacter actinomycetemcomitans Leukotoxin Mutation on Adherence Properties Are Clarified in in vitro Experiments

Senthil Kumar Velusamy, Vandana Sampathkumar, Dipti Godboley, Daniel H. Fine

published 15 Mar 2016

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Generation and Characterization of a Human/Mouse Chimeric GD₂-Mimicking Anti-Idiotype Antibody Ganglidiximab for Active Immunotherapy against Neuroblastoma

Christin Eger, Nikolai Siebert, Diana Seidel, Maxi Zumpe, Madlen Jüttner, Sven Brandt, Hans-Peter Müller, Holger N. Lode

published 11 Mar 2016

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In Vitro and In Vivo Characterization of the Alkaloid Nuciferine

Martilias S. Farrell, John D. McCorvy, Xi-Ping Huang, Daniel J. Urban, Kate L. White, Patrick M. Giguere, Allison K. Doak, Alison I. Bernstein, Kristen A. Stout, Su Mi Park, Ramona M. Rodriguiz, Bradley W. Gray, William S. Hyatt, Andrew P. Norwood, Kevin A. Webster, Brenda M. Gannon, Gary W. Miller, Joseph H. Porter, Brian K. Shoichet, William E. Fantegrossi, William C. Wetsel, Bryan L. Roth

published 10 Mar 2016

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DNA Sequence Determinants Controlling Affinity, Stability and Shape of DNA Complexes Bound by the Nucleoid Protein Fis

Stephen P. Hancock, Stefano Stella, Duilio Cascio, Reid C. Johnson

published 09 Mar 2016

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Inhibition of CXCR4 by LY2624587, a Fully Humanized Anti-CXCR4 Antibody Induces Apoptosis of Hematologic Malignancies

Sheng-Bin Peng, Xiaoyi Zhang, Donald Paul, Lisa M. Kays, Ming Ye, Peter Vaillancourt, Michele Dowless, Louis F. Stancato, Julie Stewart, Mark T. Uhlik, Haiyan Long, Shaoyou Chu, Victor H. Obungu

published 08 Mar 2016

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Genome Wide Mapping of NR4A Binding Reveals Cooperativity with ETS Factors to Promote Epigenetic Activation of Distal Enhancers in Acute Myeloid Leukemia Cells

Ryan P. Duren, Seth P. Boudreaux, Orla M. Conneely

published 03 Mar 2016

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Transcriptional Regulation of CYP2B6 Expression by Hepatocyte Nuclear Factor 3β in Human Liver Cells

Linhao Li, Daochuan Li, Scott Heyward, Hongbing Wang

published 01 Mar 2016

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Computational Characterization of Osteoporosis Associated SNPs and Genes Identified by Genome-Wide Association Studies

Longjuan Qin, Yuyong Liu, Ya Wang, Guiju Wu, Jie Chen, Weiyuan Ye, Jiancai Yang, Qingyang Huang

published 01 Mar 2016

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Structure-Activity Relationship Studies of N- and C-Terminally Modified Secretin Analogs for the Human Secretin Receptor

Kailash Singh, Vijayalakshmi Senthil, Aloysius Wilfred Raj Arokiaraj, Jérôme Leprince, Benjamin Lefranc, David Vaudry, Ahmed A. Allam, Jamaan Ajarem, Billy K. C. Chow

published 01 Mar 2016

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Affinity Enhancement by Ligand Clustering Effect Inspired by Peptide Dendrimers−Shank PDZ Proteins Interactions

Jiahui Liu, Miao Liu, Bo Zheng, Zhongping Yao, Jiang Xia

published 26 Feb 2016

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Molecular Probing of the HPV-16 E6 Protein Alpha Helix Binding Groove with Small Molecule Inhibitors

Anne Rietz, Dino P. Petrov, Matthew Bartolowits, Marsha DeSmet, V. Jo Davisson, Elliot J. Androphy

published 25 Feb 2016

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