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Binding analysis

SUMO targeting of a stress-tolerant Ulp1 SUMO protease

Jennifer Peek, Catherine Harvey, Dreux Gray, Danny Rosenberg, Likhitha Kolla, Reuben Levy-Myers, Rui Yin, Jonathan L. McMurry, Oliver Kerscher

published 19 Jan 2018

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The B cell death function of obinutuzumab-HDEL produced in plant (Nicotiana benthamiana L.) is equivalent to obinutuzumab produced in CHO cells

Jin Won Lee, Woon Heo, Jinu Lee, Narae Jin, Sei Mee Yoon, Ki Youl Park, Eun Yu Kim, Woo Taek Kim, Joo Young Kim

published 11 Jan 2018

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Discovery of indolylpiperazinylpyrimidines with dual-target profiles at adenosine A_2A and dopamine D₂ receptors for Parkinson's disease treatment

Yi-Ming Shao, Xiaohua Ma, Priyankar Paira, Aaron Tan, Deron Raymond Herr, Kah Leong Lim, Chee Hoe Ng, Gopalakrishnan Venkatesan, Karl-Norbert Klotz, Stephanie Federico, Giampiero Spalluto, Siew Lee Cheong, Yu Zong Chen, Giorgia Pastorin

published 05 Jan 2018

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Functional consequences of piceatannol binding to glyceraldehyde-3-phosphate dehydrogenase

Joanna Gerszon, Eligiusz Serafin, Adam Buczkowski, Sylwia Michlewska, Jakub Antoni Bielnicki, Aleksandra Rodacka

published 03 Jan 2018

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Atomistic simulations and network-based modeling of the Hsp90-Cdc37 chaperone binding with Cdk4 client protein: A mechanism of chaperoning kinase clients by exploiting weak spots of intrinsically dynamic kinase domains

Josh Czemeres, Kurt Buse, Gennady M. Verkhivker

published 21 Dec 2017

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Complementarity determining regions and frameworks contribute to the disulfide bond independent folding of intrinsically stable scFv

Anna Gąciarz, Lloyd W. Ruddock

published 18 Dec 2017

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Selection and targeting of EpCAM protein by ssDNA aptamer

Walhan Alshaer, Nida Ababneh, Mamon Hatmal, Heba Izmirli, Moujab Choukeife, Alaa Shraim, Nour Sharar, Aya Abu-Shiekah, Fadwa Odeh, Abeer Al Bawab, Abdalla Awidi, Said Ismail

published 15 Dec 2017

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The monomeric form of Neisseria DNA mimic protein DMP19 prevents DNA from binding to the histone-like HU protein

Ming-Fen Huang, Shin-Jen Lin, Tzu-Ping Ko, Yi-Ting Liao, Kai-Cheng Hsu, Hao-Ching Wang

published 08 Dec 2017

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Alpha conotoxin-BuIA globular isomer is a competitive antagonist for oleoyl-L-alpha-lysophosphatidic acid binding to LPAR6; A molecular dynamics study

Saima Younis, Sajid Rashid

published 06 Dec 2017

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Docking analysis and the possibility of prediction efficacy for an anti-IL-13 biopharmaceutical treatment with tralokinumab and lebrikizumab for bronchial asthma

Yutaka Nakamura, Aki Sugano, Mika Ohta, Yutaka Takaoka

published 20 Nov 2017

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Insights into the mechanism of isoenzyme-specific signal peptide peptidase-mediated translocation of heme oxygenase

Bianca Schaefer, Kohji Moriishi, Soenke Behrends

published 20 Nov 2017

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Low cost and open source multi-fluorescence imaging system for teaching and research in biology and bioengineering

Isaac Nuñez, Tamara Matute, Roberto Herrera, Juan Keymer, Timothy Marzullo, Timothy Rudge, Fernán Federici

published 15 Nov 2017

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Effects of cognate, non-cognate and synthetic CXCR4 and ACKR3 ligands on human lung endothelial cell barrier function

You-Hong Cheng, Jonathan M. Eby, Heather M. LaPorte, Brian F. Volkman, Matthias Majetschak

published 10 Nov 2017

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