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Binding analysis

A homogeneous SIRPα-CD47 cell-based, ligand-binding assay: Utility for small molecule drug development in immuno-oncology

Teresa L. Burgess, Joshua D. Amason, [ ... ], Thomas W. Miller

PCC0208025 (BMS202), a small molecule inhibitor of PD-L1, produces an antitumor effect in B16-F10 melanoma-bearing mice

Zhengping Hu, Pengfei Yu, [ ... ], Jingwei Tian

Brain Shuttle Neprilysin reduces central Amyloid-β levels

Christopher R. Campos, Alicia M. Kemble, [ ... ], Eduard Urich

Assessing the binding properties of the anti-PD-1 antibody landscape using label-free biosensors

Michael E. Brown, Daniel Bedinger, [ ... ], Yasmina Noubia Abdiche

Evaluating kratom alkaloids using PHASE

Christopher R. Ellis, Rebecca Racz, [ ... ], Lidiya Stavitskaya

Lack of an association between clinical INSTI-related body weight gain and direct interference with MC4 receptor (MC4R), a key central regulator of body weight

Carrie McMahon, James L. Trevaskis, [ ... ], Leigh Ann Burns-Naas

Systematic analysis of the binding behaviour of UHRF1 towards different methyl- and carboxylcytosine modification patterns at CpG dyads

Markus Schneider, Carina Trummer, [ ... ], Iris Antes

Computational study of parameter sensitivity in DevR regulated gene expression

Jagannath Das, Tarunendu Mapder, Sudip Chattopadhyay, Suman K. Banik

In Silico identification of angiotensin-converting enzyme inhibitory peptides from MRJP1

Rana Adnan Tahir, Afsheen Bashir, [ ... ], Sheikh Arslan Sehgal

A phenome-wide association study (PheWAS) in the Population Architecture using Genomics and Epidemiology (PAGE) study reveals potential pleiotropy in African Americans

Sarah A. Pendergrass, Steven Buyske, [ ... ], Dana C. Crawford

Binding and functional profiling of antibody mutants guides selection of optimal candidates as antibody drug conjugates

John C. Zwaagstra, Traian Sulea, [ ... ], Maria Luz. Jaramillo

Verification of hub genes in the expression profile of aortic dissection

Weitie Wang, Qing Liu, [ ... ], Kexiang Liu

Analysis of HER2 genomic binding in breast cancer cells identifies a global role in direct gene regulation

Aisling M. Redmond, Soleilmane Omarjee, [ ... ], Jason S. Carroll

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