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Basic cancer research

In vitro 3D drug sensitivity testing for patient-derived tumor-like cell clusters and whole-exome sequencing to personalize postoperative treatment: A study protocol for a multicenter randomized controlled trial

Xiaoyuan Qiu, Ruiqiang Li, Gengchen Xie, Ning Ning, Zhenjun Wang, Jiaolin Zhou, Ge Liu, Qingchao Tang, Zhuo He, Leilei Yang, Junyang Lu, Peng Li, Guole Lin

published 14 Jul 2025

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MiR-122 promotes metastasis of hepatoma cells by modulating RBM47-integrin alpha V-TGF-beta signaling

Lijun Mao, Hanru Yang, Ning Huang, Yao Li, Ye Sang, Chunxian Zeng

published 10 Jul 2025

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Papillary thyroid microcarcinoma and papillary thyroid carcinoma: Clinical characteristics and stratification of treatment strategies

Congcong Li, Qiang Li, Xiao Shi, Shuang Han, Xiao Song, Xueqian Li, Xuewei Zhuang

published 09 Jul 2025

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Impact of body mass index on surgical and oncological outcomes after Hyperthermic Intraperitoneal Chemotherapy (HIPEC)

Anne-Cécile Ezanno, Olivier Poudevigne, Jean-Louis Quesada, Julio Abba, Brice Malgras, Bertrand Trilling, Pierre-Yves Sage, Juliette Fischer, Marc Pocard, Catherine Arvieux, Fatah Tidadini

published 07 Jul 2025

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[¹⁸F]FDG PET/CT to reduce the need for sentinel lymph node biopsy in early-stage oral cancer: PETN0-study protocol

Roosmarijn S. Tellman, Dominique N.V. Donders, Anne I. J. Arens, Koos Boeve, Adrienne H. Brouwers, Simone E.J. Eerenstein, Sylvia L. van Egmond, Thomas J.W. Klein Nulent, W. Martin C. Klop, Martin Lacko, Jochem A.J. van der Pol, Daphne D.D. Rietbergen, Robert P. Takes, Joris Tim, Wouter V. Vogel, Gerben J.C. Zwezerijnen, Bart de Keizer, Remco de Bree

published 01 Jul 2025

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The distribution characteristics of PD-1 pathway-related immune cells in esophageal cancer tissue and their prognostic significance

Dehua Kong, Chunyan Gao, Yang Yu, Lu Yang, Ji Ma, Shimin Tang, Ying Mao, Yong Li, Na Li

published 30 Jun 2025

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Survival benefit of radical prostatectomy in bone metastatic prostate cancer stratified by disease characteristics: A SEER-based retrospective analysis

Xinxing Zhang, Yuxuan Wang

published 27 Jun 2025

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Ivermectin inhibits epithelial-to-mesenchymal transition via Wnt signaling in endocrine-resistant breast cancer cells

Kitiya Rujimongkon, Patthamapon Adchariyasakulchai, Phum Meeprasertskul, Wannarasmi Ketchart

published 26 Jun 2025

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Improving the robustness and efficiency of cell sheet protocol for breast cancer induction in animal model: A Geltrex plus Gelatin approach

Alaa T. Alshareeda, Nada Albarakati, Yasser Alshawakir, Ayidah Alghuwainem, Batla S. Al-Sowayan, Abdul Latif Khan, Abdullah Almubarak, Sarah Al-Maiman, Ahood Al Sayed, Nur Khatijah Mohd Zin, Amal S. Alhamid

published 23 Jun 2025

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Clinical impact of low bone mineral density in patients with colorectal cancer liver metastasis undergoing hepatectomy

Yuichi Aoki, Atsushi Miki, Yasunaru Sakuma, Jun Watanabe, Takehiro Kagaya, Makiko Tahara, Takumi Teratani, Kazuhiro Endo, Hideki Sasanuma, Wataru Nishimura, Hisanaga Horie, Joji Kitayama, Naohiro Sata, Hironori Yamaguchi

published 23 Jun 2025

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AKR1C2 silencing promotes ferroptosis and inhibits proliferation, migration, and invasion in lung cancer cells

Yi Cui, Zhihui Liu

published 18 Jun 2025

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A genome-wide SNP-SNP interaction analysis exploring novel interacting loci associated with the risk of recurrence in colorectal cancer

Aaron A. Curtis, Yajun Yu, Megan Carey, Yildiz E. Yilmaz, Sevtap Savas

published 18 Jun 2025

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A multicenter prospective study to determine the optimal range of lymph node dissection in pancreatic cancer surgery after neoadjuvant chemotherapy (LYMRIN-Trial): Project study by the Japan Pancreas Society and JON 2302-P

Nana Kimura, Yoshihiro Shirai, Ayaka Itoh, Katsuhisa Hirano, Kazuto Shibuya, Kenta Murotani, Makoto Ueno, Sohei Satoi, Hiroaki Nagano, Junji Furuse, Yoshifumi Takeyama, Tsutomu Fujii, LYMRIN-Trial collaborators

published 17 Jun 2025

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