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Basic cancer research

Clinical utility of circulating tumor DNA for early detection of recurrence after curative hepatectomy in patients with colorectal cancer with liver metastases: A prospective observational study protocol (CASSIOPEIA)

Akira Inoue, Yoshihiro Morimoto, Yujiro Nishizawa, Masahiro Hashimoto, Yuki Ozato, Kenta Furukawa, Masashi Hirota, Yasuhiro Miyazaki, Akira Tomokuni, Masaaki Motoori, Kazumasa Fujitani

published 20 Nov 2025

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Adjuvant Icotinib in EGFR-mutated stage IB non-small cell lung cancer with high-risk factors: A retrospective case series

Mengzhi Cheng, Jianbin Zhang, Lili Jin, Caihua Yu, Zhonghai Xie, Dong Li, Qinhua Gu, Qibin Shen

published 19 Nov 2025

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Study Protocol of SURVIVE HERoes (NCT06643585): Trastuzumab Deruxtecan for molecular relapse in HER2+/ Low early breast cancer with ctDNA positivity after primary therapy

Kerstin Pfister, Thomas W. P. Friedl, Andreas Hartkopf, Franziska Mergel, Sophia Huesmann, Forca Mehmeti, Henning Schäffler, Angelina Fink, Tatjana Braun, Sabine Heublein, Lisa Wiesmüller, Klaus Pantel, Brigitte Rack, Peter A. Fasching, Wolfgang Janni

published 19 Nov 2025

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Analytical validation of a homologous recombination deficiency signature (HRDsig) in pan-tumor tissue samples

Wenshu Li, Jeffrey A. Leibowitz, Shuoguo Wang, Louisa Walker, Chang Xu, Kuei-Ting Chen, Alexa B. Schrock, Jason Hughes, Nimesh Patel, Julia A. Elvin, Lauren L. Ritterhouse, Ethan Sokol, Garrett Frampton, Lucas Dennis, Bahar Yilmazel, Brennan Decker

published 17 Nov 2025

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In vivo investigation of STN1 downregulation in melanoma formation in adult mice following UV irradiation

Sara Knowles, Fang Wang, Maarten C. Bosland, Shobhan Gaddameedhi, Weihang Chai

published 14 Nov 2025

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Methodological approach to optimize a step-by-step deterministic linkage of SNDS data with a clinical database (FREGAT) of gastric/gastroesophageal junction adenocarcinoma in France: Pitfalls and learnings

Magali Laborey, Audrey Lajoinie, Jonatan Freilich, Emmanuelle Samalin, Olivier Bouché, Guillaume Piessen, Matthias Stoelzel, Andrew Chilelli

published 07 Nov 2025

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Hepatic arterial infusion is effective in patients with unresectable colorectal liver metastases refractory to standard systemic chemotherapy: A retrospective cohort study

Masatsugu Ishii, Osamu Itano, Hideki Iwamoto, Yuko Takami, Naomi Okada, Tetsuya Inoue, Satoshi Itano

published 06 Nov 2025

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Identification and validation of stage-specific microRNAs and target genes for prostate cancer: Utilizing bioinformatics tools for diagnostic marker discovery

Mahsa Yaghobinejad, Mohammad Naji, Ali Mohammad Alizadeh, Soheib Aryanezhad, Solmaz Khalighfard, Parisa Asadollahi, Nasrin Takzare, Tayebeh Rastegar

published 04 Nov 2025

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Machine learning-driven risk stratification for distant metastasis in gastric cancer: A comparative study of clinical features and composite indices integrated models

Shaoxue Yang, Han Lei

published 30 Oct 2025

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The recurrence and mortality risk in Luminal A breast cancer patients who lived in high pollution area

Pimwarat Srikummoon, Patrinee Traisathit, Wimrak Onchan, Chagkrit Ditsatham, Natthapat Thongsak, Nawapon Nakharutai, Salinee Thumronglaohapun, Titaporn Supasri, Phonpat Hemwan, Imjai Chitapanarux

published 17 Oct 2025

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IGF2BP2 contributes to thyroid cancer progression by enhancing the stability of m6A-modified CTSH mRNA

Liangpeng Dong, Lingyun Chen, Xiaofen Qi, Qiaochu Lu, Youwei Li, Mengqi Hou

published 16 Oct 2025

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Exploring the impact of antibody-dependent cellular phagocytosis-related genes on the prognosis of metastatic melanoma

Junhao Chen, Jiapeng He, Xiaolong Xu, Haiyan Sun, Jianglin Zhang

published 09 Oct 2025

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Predicting the axillary lymph node tumor burden in breast cancer patients using ultrasonic radiomics nomogram model

Pan Tang, Qi Zhang, Ling-cui Meng, Miao Chen, Sai-Feng He, Jian-Xing Zhang

published 07 Oct 2025

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