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Basic cancer research

PDK1, associated with glycolytic metabolism, is a potential prognostic biomarker in osteosarcoma

Jin Qi, Sihang Liu, Xufeng Hu, Xikang Luo, Yapeng Wang

published 19 Sep 2025

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Defining a need for rapid response and practical guidance for recurrent and metastatic squamous cell carcinoma of the head and neck (R/M SCCHN) management in France: A Delphi consensus

Florian Clatot, Caroline Even, Amaury Daste, Christian Borel, Jérôme Fayette, Myriam Chebbah, Solenn Le Clanche, Esma Saada

published 19 Sep 2025

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Super-enhancer-associated LINC00963 promotes metastasis of gastric cancer through epithelial-mesenchymal transition

Hong Du, Tingting Xiang, Ying Xia, Yong Jin, Fahua Deng, Wansong Xia, Hongyu Li, Shuqiang Cheng, Bingxue Lan, Sixi Wei, Cunfeng Song, Hai Huang

published 18 Sep 2025

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Development of a prostate cancer biochemical recurrence risk signature using machine learning and motor protein-related genes

Weixing Wang, Guohai Xie, Zhonggao Wu

published 16 Sep 2025

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A novel sialylation pathway mediated by extracellular vesicles in aggressive prostate cancer

Camila A. Bach, Md Niamat Hossain, Ishan J. Chaudhari, Cecilia E. Verrillo, Nicole M. Naranjo, Isabella Amoroso, Anna Testa, Samuel Sey, William K. Kelly, Susan L. Bellis, Aurelio Lorico, Ada G. Blidner, Gabriel A. Rabinovich, Lucia R. Languino

published 12 Sep 2025

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Genotype-phenotype correlations of germline mutations in exon 10 of the RET proto-oncogene from 14 MEN2A families of Ethnic Han Chinese

Feng Li, Weiying Chen, Zhenyu Chen, Bijun Lian, Xudong Fang, Hangyang Jin, Huihong Wang, Jianqiang Zhao, Yiming Zhang, Xiaoping Qi

published 11 Sep 2025

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The SURVIVE study (NCT05658172): Bringing breast cancer aftercare to the 21^stcentury: Study protocol of a Phase III clinical trial comparing liquid biopsy guided vs. Standard of care surveillance for intermediate to high-risk breast cancer survivors

Tatjana Braun, Sophia Huesmann, Kerstin Pfister, Thomas W. P. Friedl, Andreas Hartkopf, Klaus Pantel, Forca Mehmeti, Franziska Mergel, Henning Schäffler, Sabine Heublein, Lisa Wiesmüller, Brigitte Rack, Peter A. Fasching, Wolfgang Janni, Angelina Fink

published 09 Sep 2025

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Predicting one-year post-surgical recurrence in colorectal liver metastasis using CT radiomics and machine learning

Ningxin Chen, Boyang Zang, Yangjia Chen

published 29 Aug 2025

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Effects of previous cyclic loading history on subsequent cyclic hehaviour of sand

Xiangwu Luo, Wen Song

published 28 Aug 2025

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Factors associated with time until metastatic spread in patients with primary uveal melanoma: A retrospective analysis

Reinhard Told, Adrian Reumueller, Judith Kreminger, Stefan Sacu, Roman Dunavoelgyi

published 19 Aug 2025

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Risk stratification for the prediction of skeletal-related events in patients with castration-resistant prostate cancer with bone metastases

Masanori Hamada, Eiji Nakata, Ryuichi Nakahara, Shinsuke Sugihara, Haruyoshi Katayama, Takuto Itano, Tomohiro Inoue, Shota Takihira, Yoshiteru Akezaki, Toshifumi Ozaki

published 14 Aug 2025

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Downregulation of NCOA4 expression indicates poor prognosis and promotes the progression of cholangiocarcinoma

Wenlong Shen, Yi Liu, Bing Dai, Changling Qin, Yongli Fu, Xi Li, Chi Liu

published 11 Aug 2025

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Daraxonrasib, a pan-RAS inhibitor, selectively inhibits osteosarcomas with activated KRAS by halting AKT signaling and matrix metalloprotease activity

Okkeun Jung, Angelene Soto, Andrew L. Wolfe, Shahana S. Mahajan

published 08 Aug 2025

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