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Basic cancer research

Analytical validation of a homologous recombination deficiency signature (HRDsig) in pan-tumor tissue samples

Wenshu Li, Jeffrey A. Leibowitz, Shuoguo Wang, Louisa Walker, Chang Xu, Kuei-Ting Chen, Alexa B. Schrock, Jason Hughes, Nimesh Patel, Julia A. Elvin, Lauren L. Ritterhouse, Ethan Sokol, Garrett Frampton, Lucas Dennis, Bahar Yilmazel, Brennan Decker

published 17 Nov 2025

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In vivo investigation of STN1 downregulation in melanoma formation in adult mice following UV irradiation

Sara Knowles, Fang Wang, Maarten C. Bosland, Shobhan Gaddameedhi, Weihang Chai

published 14 Nov 2025

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Methodological approach to optimize a step-by-step deterministic linkage of SNDS data with a clinical database (FREGAT) of gastric/gastroesophageal junction adenocarcinoma in France: Pitfalls and learnings

Magali Laborey, Audrey Lajoinie, Jonatan Freilich, Emmanuelle Samalin, Olivier Bouché, Guillaume Piessen, Matthias Stoelzel, Andrew Chilelli

published 07 Nov 2025

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Hepatic arterial infusion is effective in patients with unresectable colorectal liver metastases refractory to standard systemic chemotherapy: A retrospective cohort study

Masatsugu Ishii, Osamu Itano, Hideki Iwamoto, Yuko Takami, Naomi Okada, Tetsuya Inoue, Satoshi Itano

published 06 Nov 2025

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Identification and validation of stage-specific microRNAs and target genes for prostate cancer: Utilizing bioinformatics tools for diagnostic marker discovery

Mahsa Yaghobinejad, Mohammad Naji, Ali Mohammad Alizadeh, Soheib Aryanezhad, Solmaz Khalighfard, Parisa Asadollahi, Nasrin Takzare, Tayebeh Rastegar

published 04 Nov 2025

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Machine learning-driven risk stratification for distant metastasis in gastric cancer: A comparative study of clinical features and composite indices integrated models

Shaoxue Yang, Han Lei

published 30 Oct 2025

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The recurrence and mortality risk in Luminal A breast cancer patients who lived in high pollution area

Pimwarat Srikummoon, Patrinee Traisathit, Wimrak Onchan, Chagkrit Ditsatham, Natthapat Thongsak, Nawapon Nakharutai, Salinee Thumronglaohapun, Titaporn Supasri, Phonpat Hemwan, Imjai Chitapanarux

published 17 Oct 2025

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IGF2BP2 contributes to thyroid cancer progression by enhancing the stability of m6A-modified CTSH mRNA

Liangpeng Dong, Lingyun Chen, Xiaofen Qi, Qiaochu Lu, Youwei Li, Mengqi Hou

published 16 Oct 2025

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Exploring the impact of antibody-dependent cellular phagocytosis-related genes on the prognosis of metastatic melanoma

Junhao Chen, Jiapeng He, Xiaolong Xu, Haiyan Sun, Jianglin Zhang

published 09 Oct 2025

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Predicting the axillary lymph node tumor burden in breast cancer patients using ultrasonic radiomics nomogram model

Pan Tang, Qi Zhang, Ling-cui Meng, Miao Chen, Sai-Feng He, Jian-Xing Zhang

published 07 Oct 2025

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Clinicopathological and prognostic exploratory study of primary metaplastic squamous cell carcinoma of the breast

Fang Zhang, Chengmin Zhou, Ye Yang, Junjie Li, Yue Ma, Jie Dai

published 30 Sep 2025

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Personal approach for cancer treatment: A meta-analysis of Phase II clinical trials

Mikhail B. Potievskiy, Elena P. Zharova, Lidia A. Nekrasova, Airat I. Garifullin, Ivan V. Korobov, Nikita E. Shevchenko, Anastasia A. Zabolotneva, Dmitriy N. Atochin, Andrei D. Kaprin, Peter V. Shegai

published 26 Sep 2025

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Prognostic value of D-dimer in treatment and follow up for patients who underwent radiotherapy in advanced lung cancer

Huriye Senay Kiziltan, Kimia Cepni

published 23 Sep 2025

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