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Antimalarials

Dihydroxyacetone suppresses mTOR nutrient signaling and induces mitochondrial stress in liver cells

Arlet Hernandez, Manoj Sonavane, Kelly R. Smith, Jensyn Seiger, Marie E. Migaud, Natalie R. Gassman

published 06 Dec 2022

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Healthcare claims-based Lyme disease case-finding algorithms in the United States: A systematic literature review

Young Hee Nam, Sarah J. Willis, Aaron B. Mendelsohn, Susan Forrow, Bradford D. Gessner, James H. Stark, Jeffrey S. Brown, Sarah Pugh

published 27 Oct 2022

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Sickle cell disease and pregnancy profile of complicated malaria in 982 pregnancies in Kinshasa

Tite Minga Mikobi, Nelly Ciombo Kamuanya, Pierre Zalagile Akilimali, Prosper Tshilobo Lukusa

published 06 Oct 2022

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Borrelia burgdorferi, the Lyme disease spirochete, possesses genetically-encoded responses to doxycycline, but not to amoxicillin

Timothy C. Saylor, Timothy Casselli, Kathryn G. Lethbridge, Jessamyn P. Moore, Katie M. Owens, Catherine A. Brissette, Wolfram R. Zückert, Brian Stevenson

published 30 Sep 2022

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Hydroxychloroquine/chloroquine for the treatment of hospitalized patients with COVID-19: An individual participant data meta-analysis

Leon Di Stefano, Elizabeth L. Ogburn, Malathi Ram, Daniel O. Scharfstein, Tianjing Li, Preeti Khanal, Sheriza N. Baksh, Nichol McBee, Joshua Gruber, Marianne R. Gildea, Megan R. Clark, Neil A. Goldenberg, Yussef Bennani, Samuel M. Brown, Whitney R. Buckel, Meredith E. Clement, Mark J. Mulligan, Jane A. O’Halloran, Adriana M. Rauseo, Wesley H. Self, Matthew W. Semler, Todd Seto, Jason E. Stout, Robert J. Ulrich, Jennifer Victory, Barbara E. Bierer, Daniel F. Hanley, Daniel Freilich, on behalf of the Pandemic Response COVID-19 Research Collaboration Platform for HCQ/CQ Pooled Analyses

published 29 Sep 2022

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Ethical considerations in deploying triple artemisinin-based combination therapies for malaria: An analysis of stakeholders’ perspectives in Burkina Faso and Nigeria

Paulina Tindana, Rosemonde Guissou, Oladimeji Akeem Bolarinwa, Fatoumata Tou, Freek de Haan, Mehul Dhorda, Arjen M. Dondorp, Chanaki Amaratunga, Olugbenga Ayodeji Mokuolu, Jean Bosco Ouedraogo, Phaik Yeong Cheah

published 09 Sep 2022

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Chloroquine alleviates the heat-induced to injure via autophagy and apoptosis mechanisms in skin cell and mouse models

Sheau-Chung Tang, Jiunn-Liang Ko, Chun-Te Lu, Pui-Ying Leong, Chu-Chyn Ou, Chih-Ting Hsu, Yu-Ping Hsiao

published 31 Aug 2022

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Antimicrobial susceptibility profiles of Mycoplasma hyorhinis strains isolated from five European countries between 2019 and 2021

Ulrich Klein, Dorottya Földi, Nikolett Belecz, Veronika Hrivnák, Zoltán Somogyi, Michele Gastaldelli, Marianna Merenda, Salvatore Catania, Arkadiusz Dors, Ute Siesenop, Philip Vyt, Zsuzsa Kreizinger, Wouter Depondt, Miklós Gyuranecz

published 11 Aug 2022

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Promising FDA-approved drugs with efflux pump inhibitory activities against clinical isolates of Staphylococcus aureus

Safaa Abdel-Aal Mohamed Abdel-Karim, Amira Mohamed Ali El-Ganiny, Mona Abdelmonem El-Sayed, Hisham Abdelmonem Abdelhamid Abbas

published 29 Jul 2022

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Comparative efficacy and safety of the artemisinin derivatives compared to quinine for treating severe malaria in children and adults: A systematic update of literature and network meta-analysis

Nicholas Nyaaba, Nana Efua Andoh, Gordon Amoh, Dominic Selorm Yao Amuzu, Mary Ansong, José M. Ordóñez-Mena, Jennifer Hirst

published 20 Jul 2022

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Practices of herbal management of malaria among trading mothers in Shai Osudoku District, Accra

Evans Osei Appiah, Stella Appiah, Ezekiel Oti-Boadi, Albert Oppong-Besse, Dorothy Baffour Awuah, Priscilla Ofosuhemaa Asiedu, Lt Emmanuel Oti-Boateng

published 18 Jul 2022

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Oral doxycycline prevents skin-associated adverse effects induced by injectable collagenase in a rodent model of capsular contracture around silicone implants

Yannick F. Diehm, Dimitra Kotsougiani-Fischer, Elena Porst, Valentin Haug, Laura C. Siegwart, Daniel Overhoff, Ulrich Kneser, Sebastian Fischer

published 06 Jul 2022

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Attributable risk factors for asymptomatic malaria and anaemia and their association with cognitive and psychomotor functions in schoolchildren of north-eastern Tanzania

Geofrey Makenga, Vito Baraka, Filbert Francis, Daniel T. R. Minja, Samwel Gesase, Edna Kyaruzi, George Mtove, Swabra Nakato, Rashid Madebe, Sif R. Søeborg, Kathrine H. Langhoff, Helle S. Hansson, Michael Alifrangis, John P. A. Lusingu, Jean-Pierre Van geertruyden

published 26 May 2022

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