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Antimalarials

Comparative efficacy and safety of the artemisinin derivatives compared to quinine for treating severe malaria in children and adults: A systematic update of literature and network meta-analysis

Nicholas Nyaaba, Nana Efua Andoh, Gordon Amoh, Dominic Selorm Yao Amuzu, Mary Ansong, José M. Ordóñez-Mena, Jennifer Hirst

published 20 Jul 2022

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Practices of herbal management of malaria among trading mothers in Shai Osudoku District, Accra

Evans Osei Appiah, Stella Appiah, Ezekiel Oti-Boadi, Albert Oppong-Besse, Dorothy Baffour Awuah, Priscilla Ofosuhemaa Asiedu, Lt Emmanuel Oti-Boateng

published 18 Jul 2022

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Oral doxycycline prevents skin-associated adverse effects induced by injectable collagenase in a rodent model of capsular contracture around silicone implants

Yannick F. Diehm, Dimitra Kotsougiani-Fischer, Elena Porst, Valentin Haug, Laura C. Siegwart, Daniel Overhoff, Ulrich Kneser, Sebastian Fischer

published 06 Jul 2022

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Attributable risk factors for asymptomatic malaria and anaemia and their association with cognitive and psychomotor functions in schoolchildren of north-eastern Tanzania

Geofrey Makenga, Vito Baraka, Filbert Francis, Daniel T. R. Minja, Samwel Gesase, Edna Kyaruzi, George Mtove, Swabra Nakato, Rashid Madebe, Sif R. Søeborg, Kathrine H. Langhoff, Helle S. Hansson, Michael Alifrangis, John P. A. Lusingu, Jean-Pierre Van geertruyden

published 26 May 2022

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The monoterpene 1,8-cineole prevents cerebral edema in a murine model of severe malaria

Edgleyson C. dos Santos, Leandro S. Silva, Alessandro S. Pinheiro, Douglas E. Teixeira, Diogo B. Peruchetti, Rodrigo P. Silva-Aguiar, Camila H. C. Wendt, Kildare R. Miranda, Andrelina N. Coelho-de-Souza, José Henrique Leal-Cardoso, Celso Caruso-Neves, Ana Acacia S. Pinheiro

published 12 May 2022

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Survival of HT29 cancer cells is influenced by hepatocyte growth factor receptor inhibition through modulation of self-DNA-triggered TLR9-dependent autophagy response

Bettina Bohusné Barta, Ágnes Simon, Lőrinc Nagy, Titanilla Dankó, Regina Eszter Raffay, Gábor Petővári, Viktória Zsiros, Anna Sebestyén, Ferenc Sipos, Györgyi Műzes

published 12 May 2022

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Prevalence of arps10, fd, pfmdr-2, pfcrt and pfkelch13 gene mutations in Plasmodium falciparum parasite population in Uganda

Moses Ocan, Fred Katabazi Ashaba, Savannah Mwesigwa, Kigozi Edgar, Moses R. Kamya, Sam L. Nsobya

published 05 May 2022

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Evaluation of blood cell count parameters as predictors of treatment failure of malaria in Angola: An observational study

Euclides Nenga Manuel Sacomboio, Cruz dos Santos Sebastião, Silvana Teresa da Costa Salvador, Joaquim António João, Daisy Viviana Sebastião Bapolo, Ngiambudulu M. Francisco, Joana Morais, Eduardo Ekundi Valentim

published 05 May 2022

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Chloroquine and COVID-19—A systems biology model uncovers the drug’s detrimental effect on autophagy and explains its failure

Orsolya Kapuy, Tamás Korcsmáros

published 07 Apr 2022

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Therapeutic efficacy of artemether-lumefantrine, artesunate-amodiaquine and dihydroartemisinin-piperaquine in the treatment of uncomplicated Plasmodium falciparum malaria in Sub-Saharan Africa: A systematic review and meta-analysis

Karol Marwa, Anthony Kapesa, Vito Baraka, Evelyne Konje, Benson Kidenya, Jackson Mukonzo, Erasmus Kamugisha, Gote Swedberg

published 10 Mar 2022

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Molecular profiling of the artemisinin resistance Kelch 13 gene in Plasmodium falciparum from Nigeria

Fehintola V. Ajogbasile, Paul E. Oluniyi, Adeyemi T. Kayode, Kazeem O. Akano, Benjamin B. Adegboyega, Courage Philip, Nnenna Ogbulafor, Henrietta U. Okafor, Stephen Oguche, Robinson D. Wammanda, Olugbenga A. Mokuolu, Onikepe A. Folarin, Christian T. Happi

published 28 Feb 2022

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Considerations and practical implications of performing a phenotypic CRISPR/Cas survival screen

Ator Ashoti, Francesco Limone, Melissa van Kranenburg, Anna Alemany, Mirna Baak, Judith Vivié, Frederica Piccioni, Pascale F. Dijkers, Menno Creyghton, Kevin Eggan, Niels Geijsen

published 17 Feb 2022

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A PDK-1 allosteric agonist neutralizes insulin signaling derangements and beta-amyloid toxicity in neuronal cells and in vitro

Henry Querfurth, John Marshall, Keykavous Parang, Mengia S. Rioult-Pedotti, Rakesh Tiwari, Bumsup Kwon, Steve Reisinger, Han-Kyu Lee

published 21 Jan 2022

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