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Antimalarials

Doxycycline for the prevention of progression of COVID-19 to severe disease requiring intensive care unit (ICU) admission: A randomized, controlled, open-label, parallel group trial (DOXPREVENT.ICU)

Raja Dhar, John Kirkpatrick, Laura Gilbert, Arjun Khanna, Mahavir Madhavdas Modi, Rakesh K. Chawla, Sonia Dalal, Venkata Nagarjuna Maturu, Marcel Stern, Oliver T. Keppler, Ratko Djukanovic, Stephan D. Gadola

published 23 Jan 2023

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Therapeutic efficacy of Chloroquine for the treatment of uncomplicated Plasmodium vivax infection in Shewa Robit, Northeast Ethiopia

Habtamu Belay, Megbaru Alemu, Tadesse Hailu, Hussein Mohammed, Heven Sime, Henok Hailegeorgies, Bokretsion Gidey, Mebrahtom Haile, Gudissa Assefa, Worku Bekele, Mihreteab Alebachew Reta, Andargachew Almaw Tamene, Geremew Tasew, Ashenafi Assefa

published 12 Jan 2023

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Burden of and factors associated with poor quality antibiotic, antimalarial, antihypertensive and antidiabetic medicines in Malawi

Francis Kachidza Chiumia, Happy Magwaza Nyirongo, Elizabeth Kampira, Adamson Sinjani Muula, Felix Khuluza

published 27 Dec 2022

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Factors influencing intermittent preventive treatment for malaria prevention among pregnant women accessing antenatal care in selected primary health care facilities of Bwari Area Council, Abuja Nigeria

Grace Olufunke Peters, Mergan Naidoo

published 15 Dec 2022

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Assessment of the performance and challenges in the implementation of the test, treat and track (T3) strategy for malaria control among children under-five years in Ghana

Margaret Kweku, Joyce B. Der, William K. Blankson, Haruna M. Salisu, Francis Arizie, Sorengmen A. Ziema, Jonathan M. Gmanyami, Fortress Y. Aku, Martin Adjuik

published 07 Dec 2022

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Dihydroxyacetone suppresses mTOR nutrient signaling and induces mitochondrial stress in liver cells

Arlet Hernandez, Manoj Sonavane, Kelly R. Smith, Jensyn Seiger, Marie E. Migaud, Natalie R. Gassman

published 06 Dec 2022

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Sickle cell disease and pregnancy profile of complicated malaria in 982 pregnancies in Kinshasa

Tite Minga Mikobi, Nelly Ciombo Kamuanya, Pierre Zalagile Akilimali, Prosper Tshilobo Lukusa

published 06 Oct 2022

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Borrelia burgdorferi, the Lyme disease spirochete, possesses genetically-encoded responses to doxycycline, but not to amoxicillin

Timothy C. Saylor, Timothy Casselli, Kathryn G. Lethbridge, Jessamyn P. Moore, Katie M. Owens, Catherine A. Brissette, Wolfram R. Zückert, Brian Stevenson

published 30 Sep 2022

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Hydroxychloroquine/chloroquine for the treatment of hospitalized patients with COVID-19: An individual participant data meta-analysis

Leon Di Stefano, Elizabeth L. Ogburn, Malathi Ram, Daniel O. Scharfstein, Tianjing Li, Preeti Khanal, Sheriza N. Baksh, Nichol McBee, Joshua Gruber, Marianne R. Gildea, Megan R. Clark, Neil A. Goldenberg, Yussef Bennani, Samuel M. Brown, Whitney R. Buckel, Meredith E. Clement, Mark J. Mulligan, Jane A. O’Halloran, Adriana M. Rauseo, Wesley H. Self, Matthew W. Semler, Todd Seto, Jason E. Stout, Robert J. Ulrich, Jennifer Victory, Barbara E. Bierer, Daniel F. Hanley, Daniel Freilich, on behalf of the Pandemic Response COVID-19 Research Collaboration Platform for HCQ/CQ Pooled Analyses

published 29 Sep 2022

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Ethical considerations in deploying triple artemisinin-based combination therapies for malaria: An analysis of stakeholders’ perspectives in Burkina Faso and Nigeria

Paulina Tindana, Rosemonde Guissou, Oladimeji Akeem Bolarinwa, Fatoumata Tou, Freek de Haan, Mehul Dhorda, Arjen M. Dondorp, Chanaki Amaratunga, Olugbenga Ayodeji Mokuolu, Jean Bosco Ouedraogo, Phaik Yeong Cheah

published 09 Sep 2022

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Chloroquine alleviates the heat-induced to injure via autophagy and apoptosis mechanisms in skin cell and mouse models

Sheau-Chung Tang, Jiunn-Liang Ko, Chun-Te Lu, Pui-Ying Leong, Chu-Chyn Ou, Chih-Ting Hsu, Yu-Ping Hsiao

published 31 Aug 2022

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Antimicrobial susceptibility profiles of Mycoplasma hyorhinis strains isolated from five European countries between 2019 and 2021

Ulrich Klein, Dorottya Földi, Nikolett Belecz, Veronika Hrivnák, Zoltán Somogyi, Michele Gastaldelli, Marianna Merenda, Salvatore Catania, Arkadiusz Dors, Ute Siesenop, Philip Vyt, Zsuzsa Kreizinger, Wouter Depondt, Miklós Gyuranecz

published 11 Aug 2022

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Promising FDA-approved drugs with efflux pump inhibitory activities against clinical isolates of Staphylococcus aureus

Safaa Abdel-Aal Mohamed Abdel-Karim, Amira Mohamed Ali El-Ganiny, Mona Abdelmonem El-Sayed, Hisham Abdelmonem Abdelhamid Abbas

published 29 Jul 2022

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