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Antimalarials

Heme Mediates Cytotoxicity from Artemisinin and Serves as a General Anti-Proliferation Target

Shiming Zhang, Glenn S. Gerhard

published 28 Oct 2009

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Efficacy of Artesunate + Sulfamethoxypyrazine/Pyrimethamine versus Praziquantel in the Treatment of Schistosoma haematobium in Children

Mahamadou S. Sissoko, Abdoulaye Dabo, Hamidou Traoré, Mouctar Diallo, Boubacar Traoré, Drissa Konaté, Boubacar Niaré, Moussa Diakité, Bourama Kamaté, Abdrahamane Traoré, Aboudramane Bathily, Amadou Tapily, Ousmane B. Touré, Sarah Cauwenbergh, Herwig F. Jansen, Ogobara K. Doumbo

published 05 Oct 2009

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Simple Field Assays to Check Quality of Current Artemisinin-Based Antimalarial Combination Formulations

Jean-Robert Ioset, Harparkash Kaur

published 30 Sep 2009

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Randomized Trial of Piperaquine with Sulfadoxine-Pyrimethamine or Dihydroartemisinin for Malaria Intermittent Preventive Treatment in Children

Badara Cisse, Matthew Cairns, Ernest Faye, Ousmane NDiaye, Babacar Faye, Cecile Cames, Yue Cheng, Maguette NDiaye, Aminata Collé Lô, Kirsten Simondon, Jean-Francois Trape, Oumar Faye, Jean Louis NDiaye, Oumar Gaye, Brian Greenwood, Paul Milligan

published 28 Sep 2009

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Biphasic Myopathic Phenotype of Mouse DUX, an ORF within Conserved FSHD-Related Repeats

Darko Bosnakovski, Randy S. Daughters, Zhaohui Xu, Jonathan M. W. Slack, Michael Kyba

published 16 Sep 2009

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Overexpression of Transcription Factor Sp1 Leads to Gene Expression Perturbations and Cell Cycle Inhibition

Emmanuelle Deniaud, Joël Baguet, Roxane Chalard, Bariza Blanquier, Lilia Brinza, Julien Meunier, Marie-Cécile Michallet, Aurélie Laugraud, Claudette Ah-Soon, Anne Wierinckx, Marc Castellazzi, Joël Lachuer, Christian Gautier, Jacqueline Marvel, Yann Leverrier

published 15 Sep 2009

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Activation of PyMT in β Cells Induces Irreversible Hyperplasia, but Oncogene-Dependent Acinar Cell Carcinomas When Activated in Pancreatic Progenitors

Yi-Chieh Nancy Du, David S. Klimstra, Harold Varmus

published 07 Sep 2009

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Oleic Acid Biosynthesis in Plasmodium falciparum: Characterization of the Stearoyl-CoA Desaturase and Investigation as a Potential Therapeutic Target

Paul Gratraud, Enlli Huws, Brie Falkard, Sophie Adjalley, David A. Fidock, Laurence Berry, William R. Jacobs Jr., Mark S. Baird, Henri Vial, Laurent Kremer

published 03 Sep 2009

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Piloting the Global Subsidy: The Impact of Subsidized Artemisinin-Based Combination Therapies Distributed through Private Drug Shops in Rural Tanzania

Oliver J. Sabot, Alex Mwita, Justin M. Cohen, Yahya Ipuge, Megumi Gordon, David Bishop, Moses Odhiambo, Lorrayne Ward, Catherine Goodman

published 02 Sep 2009

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No Seasonal Accumulation of Resistant P. falciparum when High-Dose Chloroquine Is Used

Johan Ursing, Poul-Erik Kofoed, Amabelia Rodrigues, Lars Rombo

published 31 Aug 2009

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Effects of Point Mutations in Plasmodium falciparum Dihydrofolate Reductase and Dihydropterate Synthase Genes on Clinical Outcomes and In Vitro Susceptibility to Sulfadoxine and Pyrimethamine

David J. Bacon, Doug Tang, Carola Salas, Norma Roncal, Carmen Lucas, Lucia Gerena, Lorena Tapia, A. Alejandro Llanos-Cuentas, Coralith Garcia, Lelv Solari, Dennis Kyle, Alan J. Magill

published 26 Aug 2009

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The Impact of IPTi and IPTc Interventions on Malaria Clinical Burden – In Silico Perspectives

Ricardo Águas, José M. L. Lourenço, M. Gabriela M. Gomes, Lisa J. White

published 13 Aug 2009

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Pilot Study of Essential Drug Quality in Two Major Cities in India

Roger Bate, Richard Tren, Lorraine Mooney, Kimberly Hess, Barun Mitra, Bibek Debroy, Amir Attaran

published 23 Jun 2009

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