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Antimalarials

Overexpression of Transcription Factor Sp1 Leads to Gene Expression Perturbations and Cell Cycle Inhibition

Emmanuelle Deniaud, Joël Baguet, Roxane Chalard, Bariza Blanquier, Lilia Brinza, Julien Meunier, Marie-Cécile Michallet, Aurélie Laugraud, Claudette Ah-Soon, Anne Wierinckx, Marc Castellazzi, Joël Lachuer, Christian Gautier, Jacqueline Marvel, Yann Leverrier

published 15 Sep 2009

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Activation of PyMT in β Cells Induces Irreversible Hyperplasia, but Oncogene-Dependent Acinar Cell Carcinomas When Activated in Pancreatic Progenitors

Yi-Chieh Nancy Du, David S. Klimstra, Harold Varmus

published 07 Sep 2009

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Oleic Acid Biosynthesis in Plasmodium falciparum: Characterization of the Stearoyl-CoA Desaturase and Investigation as a Potential Therapeutic Target

Paul Gratraud, Enlli Huws, Brie Falkard, Sophie Adjalley, David A. Fidock, Laurence Berry, William R. Jacobs Jr., Mark S. Baird, Henri Vial, Laurent Kremer

published 03 Sep 2009

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Piloting the Global Subsidy: The Impact of Subsidized Artemisinin-Based Combination Therapies Distributed through Private Drug Shops in Rural Tanzania

Oliver J. Sabot, Alex Mwita, Justin M. Cohen, Yahya Ipuge, Megumi Gordon, David Bishop, Moses Odhiambo, Lorrayne Ward, Catherine Goodman

published 02 Sep 2009

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No Seasonal Accumulation of Resistant P. falciparum when High-Dose Chloroquine Is Used

Johan Ursing, Poul-Erik Kofoed, Amabelia Rodrigues, Lars Rombo

published 31 Aug 2009

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Effects of Point Mutations in Plasmodium falciparum Dihydrofolate Reductase and Dihydropterate Synthase Genes on Clinical Outcomes and In Vitro Susceptibility to Sulfadoxine and Pyrimethamine

David J. Bacon, Doug Tang, Carola Salas, Norma Roncal, Carmen Lucas, Lucia Gerena, Lorena Tapia, A. Alejandro Llanos-Cuentas, Coralith Garcia, Lelv Solari, Dennis Kyle, Alan J. Magill

published 26 Aug 2009

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The Impact of IPTi and IPTc Interventions on Malaria Clinical Burden – In Silico Perspectives

Ricardo Águas, José M. L. Lourenço, M. Gabriela M. Gomes, Lisa J. White

published 13 Aug 2009

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Pilot Study of Essential Drug Quality in Two Major Cities in India

Roger Bate, Richard Tren, Lorraine Mooney, Kimberly Hess, Barun Mitra, Bibek Debroy, Amir Attaran

published 23 Jun 2009

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Strong Gametocytocidal Effect of Methylene Blue-Based Combination Therapy against Falciparum Malaria: A Randomised Controlled Trial

Boubacar Coulibaly, Augustin Zoungrana, Frank P. Mockenhaupt, R. Heiner Schirmer, Christina Klose, Ulrich Mansmann, Peter E. Meissner, Olaf Müller

published 05 May 2009

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Glucose-6-Phosphate Dehydrogenase Deficiency in an Endemic Area for Malaria in Manaus: A Cross-Sectional Survey in the Brazilian Amazon

Marli Stela Santana, Marcus Vinícius Guimarães de Lacerda, Maria das Graças Vale Barbosa, Wilson Duarte Alecrim, Maria das Graças Costa Alecrim

published 16 Apr 2009

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Randomized Trial of Artesunate+Amodiaquine, Sulfadoxine-Pyrimethamine+Amodiaquine, Chlorproguanal-Dapsone and SP for Malaria in Pregnancy in Tanzania

Theonest K. Mutabingwa, Kandi Muze, Rosalynn Ord, Marnie Briceño, Brian M. Greenwood, Chris Drakeley, Christopher J. M. Whitty

published 08 Apr 2009

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Inducible Transgenic Rat Model for Diabetes Mellitus Based on shRNA-Mediated Gene Knockdown

Katarina Kotnik, Elena Popova, Mihail Todiras, Marcelo A. Mori, Natalia Alenina, Jost Seibler, Michael Bader

published 02 Apr 2009

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Microbial Larvicide Application by a Large-Scale, Community-Based Program Reduces Malaria Infection Prevalence in Urban Dar Es Salaam, Tanzania

Yvonne Geissbühler, Khadija Kannady, Prosper Pius Chaki, Basiliana Emidi, Nicodem James Govella, Valeliana Mayagaya, Michael Kiama, Deo Mtasiwa, Hassan Mshinda, Steven William Lindsay, Marcel Tanner, Ulrike Fillinger, Marcia Caldas de Castro, Gerry Francis Killeen

published 31 Mar 2009

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