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Antimalarials

Heme Mediates Cytotoxicity from Artemisinin and Serves as a General Anti-Proliferation Target

Shiming Zhang, Glenn S. Gerhard

Efficacy of Artesunate + Sulfamethoxypyrazine/Pyrimethamine versus Praziquantel in the Treatment of Schistosoma haematobium in Children

Mahamadou S. Sissoko, Abdoulaye Dabo, [ ... ], Ogobara K. Doumbo

Simple Field Assays to Check Quality of Current Artemisinin-Based Antimalarial Combination Formulations

Jean-Robert Ioset, Harparkash Kaur

Randomized Trial of Piperaquine with Sulfadoxine-Pyrimethamine or Dihydroartemisinin for Malaria Intermittent Preventive Treatment in Children

Badara Cisse, Matthew Cairns, [ ... ], Paul Milligan

Biphasic Myopathic Phenotype of Mouse DUX, an ORF within Conserved FSHD-Related Repeats

Darko Bosnakovski, Randy S. Daughters, [ ... ], Michael Kyba

Overexpression of Transcription Factor Sp1 Leads to Gene Expression Perturbations and Cell Cycle Inhibition

Emmanuelle Deniaud, Joël Baguet, [ ... ], Yann Leverrier

Activation of PyMT in β Cells Induces Irreversible Hyperplasia, but Oncogene-Dependent Acinar Cell Carcinomas When Activated in Pancreatic Progenitors

Yi-Chieh Nancy Du, David S. Klimstra, Harold Varmus

Oleic Acid Biosynthesis in Plasmodium falciparum: Characterization of the Stearoyl-CoA Desaturase and Investigation as a Potential Therapeutic Target

Paul Gratraud, Enlli Huws, [ ... ], Laurent Kremer

Piloting the Global Subsidy: The Impact of Subsidized Artemisinin-Based Combination Therapies Distributed through Private Drug Shops in Rural Tanzania

Oliver J. Sabot, Alex Mwita, [ ... ], Catherine Goodman

No Seasonal Accumulation of Resistant P. falciparum when High-Dose Chloroquine Is Used

Johan Ursing, Poul-Erik Kofoed, Amabelia Rodrigues, Lars Rombo

Effects of Point Mutations in Plasmodium falciparum Dihydrofolate Reductase and Dihydropterate Synthase Genes on Clinical Outcomes and In Vitro Susceptibility to Sulfadoxine and Pyrimethamine

David J. Bacon, Doug Tang, [ ... ], Alan J. Magill

The Impact of IPTi and IPTc Interventions on Malaria Clinical Burden – In Silico Perspectives

Ricardo Águas, José M. L. Lourenço, M. Gabriela M. Gomes, Lisa J. White

Pilot Study of Essential Drug Quality in Two Major Cities in India

Roger Bate, Richard Tren, [ ... ], Amir Attaran

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