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Antimalarials

Chloroquine Clinical Failures in P. falciparum Malaria Are Associated with Mutant Pfmdr-1, Not Pfcrt in Madagascar

Valérie Andriantsoanirina, Arsène Ratsimbasoa, Christiane Bouchier, Magali Tichit, Martial Jahevitra, Stéphane Rabearimanana, Rogelin Raherinjafy, Odile Mercereau-Puijalon, Rémy Durand, Didier Ménard

published 13 Oct 2010

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Identification of Thioaptamer Ligand against E-Selectin: Potential Application for Inflamed Vasculature Targeting

Aman P. Mann, Anoma Somasunderam, René Nieves-Alicea, Xin Li, Austin Hu, Anil K. Sood, Mauro Ferrari, David G. Gorenstein, Takemi Tanaka

published 30 Sep 2010

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Protective Efficacy of Intermittent Preventive Treatment of Malaria in Infants (IPTi) Using Sulfadoxine-Pyrimethamine and Parasite Resistance

Jamie T. Griffin, Matthew Cairns, Azra C. Ghani, Cally Roper, David Schellenberg, Ilona Carneiro, Robert D. Newman, Martin P. Grobusch, Brian Greenwood, Daniel Chandramohan, Roly D. Gosling

published 07 Sep 2010

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An Economic Evaluation of Home Management of Malaria in Uganda: An Interactive Markov Model

Yoel Lubell, Anne J. Mills, Christopher J. M. Whitty, Sarah G. Staedke

published 27 Aug 2010

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Antimalarial Exposure Delays Plasmodium falciparum Intra-Erythrocytic Cycle and Drives Drug Transporter Genes Expression

Maria Isabel Veiga, Pedro Eduardo Ferreira, Berit Aydin Schmidt, Ulf Ribacke, Anders Björkman, Ales Tichopad, José Pedro Gil

published 25 Aug 2010

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Who Gets Prompt Access to Artemisinin-Based Combination Therapy? A Prospective Community-Based Study in Children from Rural Kilosa, Tanzania

Daudi O. Simba, Marian Warsame, Deodatus Kakoko, Zakayo Mrango, Goran Tomson, Zul Premji, Max Petzold

published 10 Aug 2010

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Characterization of a Temperature-Sensitive Vertebrate Clathrin Heavy Chain Mutant as a Tool to Study Clathrin-Dependent Events In Vivo

Petra Neumann-Staubitz, Stephanie L. Hall, Joseph Kuo, Antony P. Jackson

published 06 Aug 2010

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An Open-Label, Randomised Study of Dihydroartemisinin-Piperaquine Versus Artesunate-Mefloquine for Falciparum Malaria in Asia

Neena Valecha, Aung Pyae Phyo, Mayfong Mayxay, Paul N. Newton, Srivicha Krudsood, Sommay Keomany, Maniphone Khanthavong, Tiengkham Pongvongsa, Ronnatrai Ruangveerayuth, Chirapong Uthaisil, David Ubben, Stephan Duparc, Antonella Bacchieri, Marco Corsi, Bappanad H. K. Rao, Prabash C. Bhattacharya, Nagesh Dubhashi, Susanta K. Ghosh, Vas Dev, Ashwani Kumar, Sasithon Pukittayakamee

published 30 Jul 2010

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Incidence of Malaria and Efficacy of Combination Antimalarial Therapies over 4 Years in an Urban Cohort of Ugandan Children

Tamara D. Clark, Denise Njama-Meya, Bridget Nzarubara, Catherine Maiteki-Sebuguzi, Bryan Greenhouse, Sarah G. Staedke, Moses R. Kamya, Grant Dorsey, Philip J. Rosenthal

published 30 Jul 2010

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Conditional HIF-1α Expression Produces a Reversible Cardiomyopathy

Raffi Bekeredjian, Chad B. Walton, Keith A. MacCannell, Jennifer Ecker, Fred Kruse, Joel T. Outten, David Sutcliffe, Robert D. Gerard, Richard K. Bruick, Ralph V. Shohet

published 21 Jul 2010

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Experimental Evolution of Resistance to Artemisinin Combination Therapy Results in Amplification of the mdr1 Gene in a Rodent Malaria Parasite

Louise A. Rodrigues, Gisela Henriques, Sofia T. Borges, Paul Hunt, Cecília P. Sanchez, Axel Martinelli, Pedro Cravo

published 15 Jul 2010

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Caffeine Prevents Transcription Inhibition and P-TEFb/7SK Dissociation Following UV-Induced DNA Damage

Giuliana Napolitano, Stefano Amente, Virginia Castiglia, Barbara Gargano, Vera Ruda, Xavier Darzacq, Olivier Bensaude, Barbara Majello, Luigi Lania

published 21 Jun 2010

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The Cost-Effectiveness of Intermittent Preventive Treatment for Malaria in Infants in Sub-Saharan Africa

Lesong Conteh, Elisa Sicuri, Fatuma Manzi, Guy Hutton, Benson Obonyo, Fabrizio Tediosi, Prosper Biao, Paul Masika, Fred Matovu, Peter Otieno, Roly D. Gosling, Mary Hamel, Frank O. Odhiambo, Martin P. Grobusch, Peter G. Kremsner, Daniel Chandramohan, John J. Aponte, Andrea Egan, David Schellenberg, Eusebio Macete, Laurence Slutsker, Robert D. Newman, Pedro Alonso, Clara Menéndez, Marcel Tanner

published 15 Jun 2010

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