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Antimalarials

Assessment of the transmission blocking activity of antimalarial compounds by membrane feeding assays using natural Plasmodium falciparum gametocyte isolates from West-Africa

Noëlie B. Henry, Issiaka Soulama, Samuel S. Sermé, Judith M. Bolscher, Tonnie T. G. Huijs, Aboubacar S. Coulibaly, Salif Sombié, Nicolas Ouédraogo, Amidou Diarra, Soumanaba Zongo, Wamdaogo M. Guelbéogo, Issa Nébié, Sodiomon B. Sirima, Alfred B. Tiono, Alano Pietro, Katharine A. Collins, Koen J. Dechering, Teun Bousema

published 26 Jul 2023

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Repurposing the Medicines for Malaria Venture’s COVID Box to discover potent inhibitors of Toxoplasma gondii, and in vivo efficacy evaluation of almitrine bismesylate (MMV1804175) in chronically infected mice

Bruna Ramos dos Santos, Amanda Bruno da Silva Bellini Ramos, Renata Priscila Barros de Menezes, Marcus Tullius Scotti, Fábio Antônio Colombo, Marcos José Marques, Juliana Quero Reimão

published 07 Jul 2023

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Murine typhus is a common cause of acute febrile illness in Bandung, Indonesia

Silvita Fitri Riswari, Susantina Prodjosoewojo, Siti Rasnawati Mony, Imam Megantara, Shelly Iskandar, Wulan Mayasari, Henhen Heryaman, Quirijn de Mast, Andre van der Ven, Herman Kosasih, Bachti Alisjahbana

published 07 Jul 2023

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Elastin-targeted nanoparticles delivering doxycycline mitigate cytokine storm and reduce immune cell infiltration in LPS-mediated lung inflammation

Shivani Arora, Narendra Vyavahare

published 02 Jun 2023

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HER2 inhibition increases non-muscle myosin IIA to promote tumorigenesis in HER2+ breast cancers

Samar M. Alanazi, Wasim Feroz, Rosalin Mishra, Mary Kate Kilroy, Hima Patel, Long Yuan, Sarah J. Storr, Joan T. Garrett

published 18 May 2023

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Artemisinin suppresses aerobic glycolysis in thyroid cancer cells by downregulating HIF-1a, which is increased by the XIST/miR-93/HIF-1a pathway

Fei Yang, Jie Zhang, Zhijun Zhao, Yan Liu, Zhen Zhao, Kai Fu, Baokun Li, Jing Jin

published 10 Apr 2023

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A three years antimicrobials consumption in Ethiopia from 2017 to 2019: A cross- sectional study

Million Tirfe, Asnakech Alemu, Wondie Alemu, Mengistab Woldearegay, Getachew Asfaw, Heran Gerba, Duru Kadi, Atalay Mulu Fentie

published 06 Apr 2023

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Acceptability and perceived barriers to reactive focal mass drug administration in the context of a malaria elimination program in Magude district, Southern Mozambique: A qualitative study

Carlos Eduardo Cuinhane, Beatriz Galatas, Julia Montaña Lopez, Helder Djive, Hoticha Nhantumbo, Ilda Murato, Francisco Saúte, Pedro Aide, Khátia Munguambe, Neusa Torres

published 31 Mar 2023

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Loss of biased signaling at a G protein-coupled receptor in overexpressed systems

Angus Li, Samuel Liu, Rennica Huang, Seungkirl Ahn, Robert J. Lefkowitz

published 24 Mar 2023

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Diversity of bacterial community in the rhizosphere and bulk soil of Artemisia annua grown in highlands of Uganda

Namuli Aidah, Ogwang Patrick Engeu, Tumuhairwe John Baptist, Vincent B. Muwanika, Mayega Johnson, Bazira Joel

published 23 Mar 2023

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Prediction of improved antimalarial chemotherapy of artesunate-mefloquine in combination with mefloquine sensitive and resistant Plasmodium falciparum malaria

Teerachat Saeheng, Kesara Na-Bangchang

published 23 Feb 2023

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Adherence to the test, treat and track strategy for malaria control among prescribers, Mfantseman Municipality, Central Region, Ghana

Ernestina Esinam Agbemafle, Adolphina Addo-Lartey, Magdalene Akos Odikro, Joseph Asamoah Frimpong, Chrysantus Kubio, Donne Kofi Ameme, Samuel Oko Sackey, Harriet Affran Bonful

published 21 Feb 2023

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Using a data-driven approach for the development and evaluation of phenotype algorithms for systemic lupus erythematosus

Joel N. Swerdel, Darmendra Ramcharran, Jill Hardin

published 16 Feb 2023

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