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Antimalarials

Novel Polymorphisms in Plasmodium falciparum ABC Transporter Genes Are Associated with Major ACT Antimalarial Drug Resistance

Maria Isabel Veiga, Pedro Eduardo Ferreira, Louise Jörnhagen, Maja Malmberg, Aminatou Kone, Berit Aydin Schmidt, Max Petzold, Anders Björkman, Francois Nosten, Jose Pedro Gil

published 25 May 2011

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The Potential Contribution of Mass Treatment to the Control of Plasmodium falciparum Malaria

Lucy C. Okell, Jamie T. Griffin, Immo Kleinschmidt, T. Déirdre Hollingsworth, Thomas S. Churcher, Michael J. White, Teun Bousema, Chris J. Drakeley, Azra C. Ghani

published 24 May 2011

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Fitness Trade-Offs in the Evolution of Dihydrofolate Reductase and Drug Resistance in Plasmodium falciparum

Marna S. Costanzo, Kyle M. Brown, Daniel L. Hartl

published 23 May 2011

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Decreased Proliferation Kinetics of Mouse Myoblasts Overexpressing FRG1

Steven C. Chen, Ellie Frett, Joseph Marx, Darko Bosnakovski, Xylena Reed, Michael Kyba, Brian K. Kennedy

published 16 May 2011

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Artesunate Dose Escalation for the Treatment of Uncomplicated Malaria in a Region of Reported Artemisinin Resistance: A Randomized Clinical Trial

Delia Bethell, Youry Se, Chanthap Lon, Stuart Tyner, David Saunders, Sabaithip Sriwichai, Sea Darapiseth, Paktiya Teja-Isavadharm, Phisit Khemawoot, Kurt Schaecher, Wiriya Ruttvisutinunt, Jessica Lin, Worachet Kuntawungin, Panita Gosi, Ans Timmermans, Bryan Smith, Duong Socheat, Mark M. Fukuda

published 13 May 2011

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UMP/CMPK Is Not the Critical Enzyme in the Metabolism of Pyrimidine Ribonucleotide and Activation of Deoxycytidine Analogs in Human RKO Cells

Rong Hu, Wing Lam, Chih-Hung Hsu, Yung-Chi Cheng

published 03 May 2011

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The Structural Features of Trask That Mediate Its Anti-Adhesive Functions

Danislav S. Spassov, Deepika Ahuja, Ching Hang Wong, Mark M. Moasser

published 29 Apr 2011

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Modelling the Protective Efficacy of Alternative Delivery Schedules for Intermittent Preventive Treatment of Malaria in Infants and Children

Matthew Cairns, Azra Ghani, Lucy Okell, Roly Gosling, Ilona Carneiro, Francis Anto, Victor Asoala, Seth Owusu-Agyei, Brian Greenwood, Daniel Chandramohan, Paul Milligan

published 20 Apr 2011

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Functional Energetics of CD4⁺-Cellular Immunity in Monoclonal Antibody-Associated Progressive Multifocal Leukoencephalopathy in Autoimmune Disorders

Aiden Haghikia, Moritz Perrech, Bartosz Pula, Sabrina Ruhrmann, Anja Potthoff, Norbert H. Brockmeyer, Susan Goelz, Heinz Wiendl, Hans Lindå, Tjalf Ziemssen, Sergio E. Baranzini, Tor-Björn Käll, Dietmar Bengel, Tomas Olsson, Ralf Gold, Andrew Chan

published 20 Apr 2011

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The Candida albicans-Specific Gene EED1 Encodes a Key Regulator of Hyphal Extension

Ronny Martin, Gary P. Moran, Ilse D. Jacobsen, Antje Heyken, Jenny Domey, Derek J. Sullivan, Oliver Kurzai, Bernhard Hube

published 07 Apr 2011

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Determinants of the Cost-Effectiveness of Intermittent Preventive Treatment for Malaria in Infants and Children

Amanda Ross, Nicolas Maire, Elisa Sicuri, Thomas Smith, Lesong Conteh

published 07 Apr 2011

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Major Reduction in Anti-Malarial Drug Consumption in Senegal after Nation-Wide Introduction of Malaria Rapid Diagnostic Tests

Sylla Thiam, Moussa Thior, Babacar Faye, Médoune Ndiop, Mamadou Lamine Diouf, Mame Birame Diouf, Ibrahima Diallo, Fatou Ba Fall, Jean Louis Ndiaye, Audrey Albertini, Evan Lee, Pernille Jorgensen, Oumar Gaye, David Bell

published 06 Apr 2011

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Towards an In Vitro Model of Plasmodium Hypnozoites Suitable for Drug Discovery

Laurent Dembele, Audrey Gego, Anne-Marie Zeeman, Jean-François Franetich, Olivier Silvie, Armelle Rametti, Roger Le Grand, Nathalie Dereuddre-Bosquet, Robert Sauerwein, Geert-Jan van Gemert, Jean-Christophe Vaillant, Alan W. Thomas, Georges Snounou, Clemens H. M. Kocken, Dominique Mazier

published 31 Mar 2011

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