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Antimalarials

The Potential Role of Metalloproteinases in Neurogenesis in the Gerbil Hippocampus Following Global Forebrain Ischemia

Luiza Wójcik-Stanaszek, Joanna Sypecka, Patrycja Szymczak, Malgorzata Ziemka-Nalecz, Michel Khrestchatisky, Santiago Rivera, Teresa Zalewska

published 25 Jul 2011

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Antimalarial Activity of Potential Inhibitors of Plasmodium falciparum Lactate Dehydrogenase Enzyme Selected by Docking Studies

Julia Penna-Coutinho, Wilian Augusto Cortopassi, Aline Alves Oliveira, Tanos Celmar Costa França, Antoniana Ursine Krettli

published 14 Jul 2011

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Protein Phosphatase 1 (PP1) Is a Post-Translational Regulator of the Mammalian Circadian Clock

Isabelle Schmutz, Sabrina Wendt, Anna Schnell, Achim Kramer, Isabelle M. Mansuy, Urs Albrecht

published 21 Jun 2011

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Resistance of a Rodent Malaria Parasite to a Thymidylate Synthase Inhibitor Induces an Apoptotic Parasite Death and Imposes a Huge Cost of Fitness

Francis W. Muregi, Isao Ohta, Uchijima Masato, Hideto Kino, Akira Ishih

published 16 Jun 2011

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Anti-Malarial Drug Artesunate Attenuates Experimental Allergic Asthma via Inhibition of the Phosphoinositide 3-Kinase/Akt Pathway

Chang Cheng, W. Eugene Ho, Fera Y. Goh, Shou Ping Guan, Li Ren Kong, Wen-Qi Lai, Bernard P. Leung, W. S. Fred Wong

published 09 Jun 2011

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Development of Resistance towards Artesunate in MDA-MB-231 Human Breast Cancer Cells

Beatrice Bachmeier, Iduna Fichtner, Peter H. Killian, Emanuel Kronski, Ulrich Pfeffer, Thomas Efferth

published 26 May 2011

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Validation of the Tetracycline Regulatable Gene Expression System for the Study of the Pathogenesis of Infectious Disease

Ashok K. Chaturvedi, Anna L. Lazzell, Stephen P. Saville, Floyd L. Wormley Jr., Carlos Monteagudo, Jose L. Lopez-Ribot

published 25 May 2011

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Novel Polymorphisms in Plasmodium falciparum ABC Transporter Genes Are Associated with Major ACT Antimalarial Drug Resistance

Maria Isabel Veiga, Pedro Eduardo Ferreira, Louise Jörnhagen, Maja Malmberg, Aminatou Kone, Berit Aydin Schmidt, Max Petzold, Anders Björkman, Francois Nosten, Jose Pedro Gil

published 25 May 2011

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The Potential Contribution of Mass Treatment to the Control of Plasmodium falciparum Malaria

Lucy C. Okell, Jamie T. Griffin, Immo Kleinschmidt, T. Déirdre Hollingsworth, Thomas S. Churcher, Michael J. White, Teun Bousema, Chris J. Drakeley, Azra C. Ghani

published 24 May 2011

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Fitness Trade-Offs in the Evolution of Dihydrofolate Reductase and Drug Resistance in Plasmodium falciparum

Marna S. Costanzo, Kyle M. Brown, Daniel L. Hartl

published 23 May 2011

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Decreased Proliferation Kinetics of Mouse Myoblasts Overexpressing FRG1

Steven C. Chen, Ellie Frett, Joseph Marx, Darko Bosnakovski, Xylena Reed, Michael Kyba, Brian K. Kennedy

published 16 May 2011

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Artesunate Dose Escalation for the Treatment of Uncomplicated Malaria in a Region of Reported Artemisinin Resistance: A Randomized Clinical Trial

Delia Bethell, Youry Se, Chanthap Lon, Stuart Tyner, David Saunders, Sabaithip Sriwichai, Sea Darapiseth, Paktiya Teja-Isavadharm, Phisit Khemawoot, Kurt Schaecher, Wiriya Ruttvisutinunt, Jessica Lin, Worachet Kuntawungin, Panita Gosi, Ans Timmermans, Bryan Smith, Duong Socheat, Mark M. Fukuda

published 13 May 2011

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UMP/CMPK Is Not the Critical Enzyme in the Metabolism of Pyrimidine Ribonucleotide and Activation of Deoxycytidine Analogs in Human RKO Cells

Rong Hu, Wing Lam, Chih-Hung Hsu, Yung-Chi Cheng

published 03 May 2011

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