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Antimalarials

Dual function of mitochondrial complex III in Plasmodium falciparum

River S. Rell, Anurag Shukla, Joanne M. Morrisey, Ijeoma C. Okoye, Michael W. Mather, Akhil B. Vaidya

published 20 Feb 2026

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In silico evaluation of bioactive compounds from the sea urchin Temnopleurus toreumaticus: Potential multifunctional agents against mosquito vectors and tropical pathogens

Karnan Ramachandran, Senthil Bakthavatchalam, Velavan Sivanandham, Shunmuga Vadivu Ramalingam, Pitchaimuthu Mariappan, Renganathan Senthil, Chandramohan Govindasamy, Khalid S. Al-Numair, Ramachandran Vinayagam, Zhi-Hong Wen, Hsien-Kuo Chin

published 23 Jan 2026

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Computational screening of natural inhibitors against Plasmodium falciparum kinases: Toward novel antimalarial therapies

Muharib Alruwaili, Sonia Younas, Abozer Y. Elderdery, Intisar Alruwaili, Jeremy Millis, Muhammad Umer Khan, Hasan Ejaz

published 13 Jan 2026

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Rational design of novel Plasmodium falciparum glutamyl-tRNA synthetase inhibitors for the development of next-generation antimalarial drugs

Wesam Nofal

published 04 Dec 2025

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Investigating barriers to adherence to antimalarial prescribing guidelines in public healthcare facilities in Arba Minch, South Ethiopia: A qualitative study

Abate Atimut Dereje, Dereje Geleta, Tadesse Menjetta, Abinet Takele, Susana Vaz Nery, Techalew Shimelis

published 26 Nov 2025

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Prevalence and associated factors of delay in seeking malaria treatment among under five children in the Horn of Africa: A systematic review and meta-analysis

Muluken Chanie Agimas, Mekuriaw Nibret Aweke, Berhanu Mengistu, Lemlem Daniel Baffa, Elsa Awoke Fentie, Ever Siyoum Shewarega, Aysheshim Kassahun Belew, Esmael Ali Muhammad

published 26 Sep 2025

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Drug-induced vitiligo: a real-world pharmacovigilance analysis of the FAERS database

Nonger Shen, Qingxia Fang, Yue Wu, Lan Lan, Fangfang Ma

published 08 Sep 2025

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Cadinapyridine sesquiterpene alkaloids from Artemisia annua and in vitro cytotoxicity and antiplasmodial activities

Nicolas Fabre, Adrien Vitrai, Sandra Bourgeade-Delmas, Nathalie Saffon-Merceron, Abdou Madjid Olatoundé Amoussa, Latifou Lagnika, Agnès Aubouy, Valérie Jullian

published 03 Sep 2025

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Antimalarial and neuroprotective effects of ethanolic extracts of the five-flower remedy in an experimental cerebral malaria model

Walaiporn Plirat, Prapaporn Chaniad, Arisara Phuwajaroanpong, Atthaphon Konyanee, Laddawan Lalert, Abdi Wira Septama, Chuchard Punsawad

published 02 Sep 2025

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Comparison of the composition and antiplasmodial activity of Artemisia annua teas using an untargeted metabolomic approach

Agnès Aubouy, Abdou Madjid Olatoundé Amoussa, Latifou Lagnika, Nicolas Fabre, Adrien Vitrai, Catherine Claparols, Sandrine Houzé, Véronique Sarrasin, Florence Chapeland-Leclerc, Gwenaël Ruprich-Robert, Sandra Bourgeade-Delmas, Hounnankpon Yedomonhan, Charlotte Dumondin, Valérie Jullian

published 22 Aug 2025

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Artesunate regulates malignant progression of breast cancer cells via lncRNA TUG1/miR-145-5p/HOXA5 axis

Chao Yang, Yunjiang Liu, Lingyun Gai, Ziteng Zhang, Yanshou Zhang, Geng Zhang, Kaiye Du, Chao Gao

published 04 Aug 2025

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CYP2B6*6 single nucleotide polymorphism among patients with uncomplicated malaria in Adjumani district, Uganda: Implications on efficacy of artemether-lumefantrine

Martin Kamilo Angwe, Norah Mwebaza, Sam Lubwama Nsobya, Ronald Kiguba, Patrick Vudriko, Saviour Dralabu, Denis Omali, Maria Agnes Tumwebaze, Moses Ocan

published 01 Aug 2025

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A non-enzymatic doxycycline absorbance sensor based on manganese-doped zinc sulfide nanoparticles coated with chitosan

Son Hai Nguyen, Mai Thi Tran

published 14 Jul 2025

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