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Animal models of disease

Culture media affects accuracy of prediction of metallo-β-lactamases mediated resistance to imipenem

Kexuan Chen, Sarah Miller, Kristine Goy, Tina Lam, Marlène Maeusli, Rosemary She, Brad Spellberg, Brian Luna

published 28 Jan 2026

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Distinct transcriptomic effects of intermittent and chronic caloric restriction in mammary fat pad of a breast cancer mouse model

Bilge Guvenc Tuna, Nazim Arda Keles, Munevver Burcu Cicekdal, Soner Dogan, Sulev Koks

published 23 Sep 2025

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Active electroceutical treatment of Pseudomonas aeruginosa infected murine wounds

Colin R. Mack, Traci A. Wilgus, Sheri Dellos-Nolan, Tony DiCesare, Daria Bentley, Fraser J. Daniel, Vish V. Subramaniam, Sahil Mahajan, Paul Stoodley, Daniel J. Wozniak, Shaurya Prakash

published 22 Sep 2025

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Detection of Fusarium solani using cutinase antibody and its application in diagnosing fungal keratitis in an animal model

Hye-Jeong Jo, Min-Jeong Kim, Hae-Ahm Lee, Fu-Shi Quan, Hyun-Hee Kong, Eun-Kyung Moon

published 20 Aug 2025

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Development of a novel PIK3CA-mutated pancreatic tumor mouse model and evaluation of the therapeutic effects of a PI3K inhibitor

Yoshimasa Suzuki, Makoto Sugimori, Yushi Kanemaru, Sho Onodera, Hiromi Tsuchiya, Aya Ikeda, Ryosuke Ikeda, Yoshihiro Goda, Hiroaki Kaneko, Kuniyasu Irie, Soichiro Sue, Hideaki Ijichi, Shin Maeda

published 10 Jul 2025

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Hyers Ulam stability and bifurcation control of leptospirosis disease dynamics and preventations: Modeling with singular and non-singular kernels

Muhammad Farman, Aqeel Ahmad, Usama Atta, Kottakkaran Sooppy Nisar, Abdul Ghaffar

published 31 Mar 2025

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Weighted–VAE: A deep learning approach for multimodal data generation applied to experimental T. cruzi infection

Blanca Vazquez, Nidiyare Hevia-Montiel, Jorge Perez-Gonzalez, Paulina Haro

published 24 Mar 2025

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Development of a rapid antigen-based lateral flow assay for tick-borne spotted fever rickettsioses

Richard Willson, Yingxin Zhao, Kristen Brosamer, Yogita Pal, Lucas S. Blanton, Esteban Arroyave, Carsen Roach, David H. Walker, Katerina Kourentzi, Rong Fang

published 17 Jan 2025

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Intracerebroventricular administration of a modified hexosaminidase ameliorates late-stage neurodegeneration in a GM2 mouse model

Manuel E. Lopez, Daniel Wendt, Roger Lawrence, Kerui Gong, Hoonsan Ong, Bryan Yip, Joseph Chen, Linley Mangini, Britta Handyside, Alexander Giaramita, Aashish Lamichhane, Melanie Lo, Vishal Agrawal, Jeremy Van Vleet, Amanda Abolhesn, Jessica B. Felix, Isaac Villalpando, Vikas Bhat, Rolando De Angelis, Yuanbin Ru, Ayesha Khan, Sylvia Fong, Terri Christianson, Sherry Bullens, Brett E. Crawford, Stuart Bunting, Mika Aoyagi-Scharber

published 03 Jan 2025

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STEED: A data mining tool for automated extraction of experimental parameters and risk of bias items from in vivo publications

Wolfgang Emanuel Zurrer, Amelia Elaine Cannon, Ewoud Ewing, David Brüschweiler, Julia Bugajska, Bernard Friedrich Hild, Marianna Rosso, Daniel Salo Reich, Benjamin Victor Ineichen

published 26 Nov 2024

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Vaginal Tritrichomonas foetus infection in mice as an in vivo model for drug development against Trichomonas vaginalis

Noelle M. Nieskens, Yukiko Miyamoto, Brianna M. Hurysz, Anthony J. O’Donoghue, Lars Eckmann

published 01 Oct 2024

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Efficacy of mefloquine and its enantiomers in a murine model of Mycobacterium avium infection

Antoine Froment, Julia Delomez, Sophie Da Nascimento, Alexandra Dassonville-Klimpt, Claire Andréjak, François Peltier, Cédric Joseph, Pascal Sonnet, Jean-Philippe Lanoix

published 30 Sep 2024

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Rv0100: An essential acyl carrier protein from M. tuberculosis important in dormancy

Hiten J. Gutka, Jasper Marc G. Bondoc, Ryan Patwell, Shahebraj Khan, Edyta M. Grzelak, Rajendra Goswami, Martin I. Voskuil, Farahnaz Movahedzadeh

published 07 Jun 2024

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