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Anatomical pathology

A public generalizable AI tool for automated segmentation of coronal brain tissue slabs for 3D neuropathology

Jonathan Williams Ramirez, Dina Zemlyanker, Lucas Deden-Binder, Rogeny Herisse, Erendira Garcia Pallares, Karthik Gopinath, Harshvardhan Gazula, Christopher Mount, Liana N. Kozanno, Michael S. Marshall, Theresa R. Connors, Matthew P. Frosch, Mark Montine, Derek H. Oakley, Christine L. Mac Donald, C. Dirk Keene, Bradley T. Hyman, Bruce Fischl, Juan E. Iglesias

published 17 Aug 2026

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A chemically optimized, GalNAc-conjugated siRNA targeting HSD17B13 demonstrates efficacy in a human 3D organoid model of MASH, showcasing an alternative to animal testing

Qin Meng, Xujia Wang, Yuxuan Zhang, Sudeep Pushpakom, Jun Yang, Hui Feng, Mu Wang

published 14 Aug 2026

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Do common dopaminergic variants modulate processing speed in cognitive aging? A longitudinal candidate gene study

Monica Anona Rose, Andrew C. Robinson, Antony Payton

published 17 Jul 2026

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Artificial intelligence-detected HER2 strong-positive tumor proportion predicts FISH positivity and treatment response in breast cancer

Seung Geun Song, Soo Ick Cho, Taeyong Sim, Sangwon Shin, Wonkyung Jung, Jisoo Shin, Sukjun Kim, Heon Song, Sérgio Pereira, Donggeun Yoo, Sun Kyung Baek, Kiyong Na, Minsun Jung, So-Woon Kim

published 06 Jul 2026

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Effect of high-intensity interval training in patients with chronic hepatitis B and hepatic steatosis: A randomised controlled trial

Sofie Jespersen, Asmita Fritt-Rasmussen, Cody Garett Durrer, Eva Fallentin, Ellen Sloth Andersen, Peter Thielsen, Thomas Bandholm, Sten Madsbad, Bente Klarlund Pedersen, Christian Ritz, Nina Weis, Rikke Krogh-Madsen

published 23 Jun 2026

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Stage-dependent dynamics of Apolipoprotein C3 across the spectrum of MASLD

Eva Katharina Messer, Janett Fischer, Toni Herta, Albrecht Boehlig, Madlen Matz-Soja, Adrienn Tuennemann-Tarr, Susanne Gaul, Ulrich Laufs, Thomas Berg

published 23 Jun 2026

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Multi-scale feature integration with enhanced cytomorph for high-accuracy cervical cytology classification

Elif İlgazi Kılıç, Şafak Kılıç

published 10 Jun 2026

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Postmastectomy radiotherapy in pN1 breast cancer: Survival outcomes and prognostic factors from a single-institution cohort

Raksha M. Narasimhan, Aren Singh Saini, Kayla Samimi, Ifeanyichukwu Ogobuiro, Xuesen Zhao, Sunwoo Han, Cristiane Takita, Crystal S. Taswell

published 01 Jun 2026

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Differences in gene expression may contribute to the racial differences in the risk of MASLD

Ivan P. Gorlov, Olga Y. Gorlova, Aaron P. Thrift

published 04 May 2026

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Exploring the association between serum vitamins and CAP-defined hepatic steatosis in lean and non-lean adults with NAFLD: A cross-sectional study

Caijuan Hong, Lili Jiang, Lulu Xia

published 13 Apr 2026

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BioFuse: an embedding fusion framework for biomedical foundation models

Mirza Nasir Hossain, David Harris-Birtill

published 18 Mar 2026

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Comparison of neonatal systemic and intracerebroventricular AAV9 gene therapy delivery demonstrating improved behavioral and phenotypic outcomes in a mouse model of Niemann-Pick disease, type C1

Benjamin E. Epstein, Gabrielle M. Soden, Arturo A. Incao, Avani Mylvara, Jonathan Flynn, Fatih Ozsolak, William J. Pavan

published 11 Mar 2026

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The association between epicardial adipose tissue thickness and diabetes mellitus, hyperlipidemia, hepatosteatosis, pancreatic steatosis and pancreatitis

Ece Zengin, Aybuke Ucgun, Mehmet Emir Çevik, Sehnaz Evrimler, Ihsaniye Suer Dogan

published 26 Feb 2026

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