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Amastigotes

A novel Leishmania infantum reference strain for gene editing and the study of visceral leishmaniasis

Rokhaya Thiam, Maria Santana Ceballos, Tom Beneke, Nada Kuk, Grégoire Pasquier, Lucien Crobu, Daniel C. Jeffares, Baptiste Vergnes, Bridlin Barckmann, Yvon Sterkers

published 03 Sep 2025

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Zinc selenide (ZnSe) nanoparticle coated with green seaweed (Ulva fasciata) hydroalcoholic extract as an anti-leishmanial compound on Leishmania major

Zahra Atef, Fatemeh Livani, Faramarz Koohsar, Roghiyeh Faridnia, Ganesh Yadagiri, Hamed Kalani

published 29 Apr 2025

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Assessment of the antileishmanial activity of diallyl sulfide combined with meglumine antimoniate on Leishmania major: Molecular docking, in vitro, and animal model

Farzaneh Zarrinkar, Iraj Sharifi, Ehsan Salarkia, Alireza Keyhani, Zahra Babaei, Ali Khamesipour, Maryam Hakimi Parizi, Elaheh Molaakbari, Fatemeh Sharifi, Shahriar Dabiri, Mehdi Bamorovat

published 30 Aug 2024

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Exploring hydrophilic 2,2-di(indol-3-yl)ethanamine derivatives against Leishmania infantum

Alessia Centanni, Aurora Diotallevi, Gloria Buffi, Diego Olivieri, Nuno Santarém, Antti Lehtinen, Jari Yli-Kauhaluoma, Anabela Cordeiro-da-Silva, Paula Kiuru, Simone Lucarini, Luca Galluzzi

published 13 Jun 2024

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Antiparasitic effect of Farnesol against Leishmania major: A rationale from in vitro and in silico investigations

Harshita Sharma, Rakesh Sehgal, Nishant Shekhar, Gaurav Shoeran, Upninder Kaur, Bikash Medhi

published 06 Nov 2023

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In silico and in vitro potentials of crocin and amphotericin B on Leishmania major: Multiple synergistic mechanisms of actions

Ehsan Salarkia, Iraj Sharifi, Alireza Keyhani, Razieh Tavakoli Oliaee, Ahmad Khosravi, Fatemeh Sharifi, Mehdi Bamorovat, Zahra Babaei

published 08 Sep 2023

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Antileishmanial potentials of azacitidine and along with meglumine antimoniate on Leishmania major: In silico prediction and in vitro analysis

Ali Derakhshani, Iraj Sharifi, Ehsan Salarkia, Alireza Keyhani, Setareh Agha Kuchak Afshari, Behzad Iranmanesh, Mahdieh Lashkarizadeh, Hamid Nejad Biglari, Moslem Lari Najafi, Mehdi Bamorovat

published 08 Sep 2023

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Evaluating leishmanicidal effects of Lucilia sericata products in combination with Apis mellifera honey using an in vitro model

Jila Sherafati, Mohammad Saaid Dayer, Fatemeh Ghaffarifar, Kamran Akbarzadeh, Majid Pirestani

published 03 Aug 2023

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Evaluation of expression variations in virulence-related genes of Leishmania major after several culture passages compared with Phlebotomus papatasi isolated promastigotes

Taher Nemati Haravani, Parviz Parvizi, Seyed Hossein Hejazi, Mohammad Mehdi Sedaghat, Abbasali Eskandarian, Mahmoud Nateghi Rostami

published 13 Apr 2023

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Identification of natural cytochalasins as leads for neglected tropical diseases drug discovery

Marilia Valli, Julia Medeiros Souza, Rafael Consolin Chelucci, Carolina Rabal Biasetto, Angela Regina Araujo, Vanderlan da Silva Bolzani, Adriano Defini Andricopulo

published 03 Oct 2022

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Effects of negative air ions (NAIs) on Leishmania major: A novel tool for treatment of zoonotic cutaneous leishmaniasis (ZCL)

Alireza Badirzadeh, Mehdi Najm, Andrew Hemphill, Maryam Alipour, Hamid Hasanpour, Leila Masoori, Poorya Karimi

published 08 Sep 2022

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Pre-clinical evaluation of LASSBio-1491: From in vitro pharmacokinetic study to in vivo leishmanicidal activity

Aline Cavalcanti de Queiroz, Gisele Barbosa, Victória Regina Thomaz de Oliveira, Hélio de Mattos Alves, Marina Amaral Alves, Vanessa Carregaro, João Santana da Silva, Eliezer Jesus Barreiro, Magna Suzana Alexandre-Moreira, Lidia Moreira Lima

published 06 Jun 2022

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The role of Leishmania GP63 in the modulation of innate inflammatory response to Leishmania major infection

Aretha Chan, Jose-Mauricio Ayala, Fernando Alvarez, Ciriaco Piccirillo, George Dong, David Langlais, Martin Olivier

published 31 Dec 2021

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