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Allosteric regulation

A dimer between monomers and hexamers—Oligomeric variations in glucosamine-6-phosphate deaminase family

Sathya Srinivasachari, Vikas R. Tiwari, [ ... ], Ramaswamy Subramanian

Slow dynamics measured by phosphorescence lifetime reveals global conformational changes in human adult hemoglobin induced by allosteric effectors

Gusztáv Schay, Judit Fidy, Levente Herenyi

A rapid and sensitive assay for quantifying the activity of both aerobic and anaerobic ribonucleotide reductases acting upon any or all substrates

Talya S. Levitz, Gisele A. Andree, [ ... ], Catherine L. Drennan

Simulation model of CA1 pyramidal neurons reveal opposing roles for the Na⁺/Ca²⁺ exchange current and Ca²⁺-activated K⁺ current during spike-timing dependent synaptic plasticity

Damien M. O’Halloran

Characterization and assembly of the Pseudomonas aeruginosa aspartate transcarbamoylase-pseudo dihydroorotase complex

Chandni Patel, Asmita Vaishnav, Brian F. P. Edwards, David R. Evans

Breast cancers utilize hypoxic glycogen stores via PYGB, the brain isoform of glycogen phosphorylase, to promote metastatic phenotypes

Megan A. Altemus, Laura E. Goo, [ ... ], Sofia D. Merajver

Extreme pathway analysis reveals the organizing rules of metabolic regulation

Yanping Xi, Fei Wang

Dissecting a novel allosteric mechanism of cruzain: A computer-aided approach

Lilian Hernández Alvarez, Diego Enry Barreto Gomes, Jorge Enrique Hernández González, Pedro Geraldo Pascutti

Dissimilar flexibility of α and β subunits of human adult hemoglobin influences the protein dynamics and its alteration induced by allosteric effectors

Gusztáv Schay, András D. Kaposi, [ ... ], Levente Herenyi

Atomistic simulations and network-based modeling of the Hsp90-Cdc37 chaperone binding with Cdk4 client protein: A mechanism of chaperoning kinase clients by exploiting weak spots of intrinsically dynamic kinase domains

Josh Czemeres, Kurt Buse, Gennady M. Verkhivker

Dependence of prevalence of contiguous pathways in proteins on structural complexity

Kelly M. Thayer, Jesse C. Galganov, Avram J. Stein

Ensemble-based modeling and rigidity decomposition of allosteric interaction networks and communication pathways in cyclin-dependent kinases: Differentiating kinase clients of the Hsp90-Cdc37 chaperone

Gabrielle Stetz, Amanda Tse, Gennady M. Verkhivker

Allosteric-activation mechanism of BK channel gating ring triggered by calcium ions

Ronghua Guan, Hui Zhou, [ ... ], Hailong An

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