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Open Access

Correction

Correction: Transcriptional profiling of Toll-like receptor 2-deficient primary murine brain cells during Toxoplasma gondii infection

  • Kousuke Umeda,
  • Sachi Tanaka,
  • Fumiaki Ihara,
  • Junya Yamagishi,
  • Yutaka Suzuki,
  • Yoshifumi Nishikawa
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The Fig 3E and 3F and Fig 4E and 4F are swapped in the Fig 3 and Fig 4. The current Fig 3E and 3F should be Fig 4E and 4F and vice versa. Please see the correct Fig 3 and Fig 4 here.

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Fig 3. Comparison of transcriptional profiles of Tlr2-/- and wild-type neurons during T. gondii infection.

Upregulated (A, C, E) and downregulated (B, D, F) genes were identified as genes with 2-fold change and < 0.05 FDR in DESeq analysis comparing infected and uninfected cells. (A, B) Venn diagrams comparing DEGs with increased and decreased abundance between Tlr2-/- and wild-type neurons. (C, D) To explore the function of DEGs analyzed in the Venn diagram, GO term enrichment analysis was performed. Asterisks represent significant differences with p < 0.05 in Fisher’s exact test. (E, F) Expression of top 20 genes highly upregulated or downregulated in a TLR2-dependent manner. TLR2-dependent DEGs were ranked according to fold-changes between infected and uninfected wild-type. WT, wild-type; KO, Tlr2-/-.

https://doi.org/10.1371/journal.pone.0303453.g001

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Fig 4. Comparison of transcriptional profiles of Tlr2-/- and wild-type macrophages during T. gondii infection.

Upregulated (A, C, E) and downregulated (B, D, F) genes were identified as genes with 2-fold change and < 0.05 FDR in DESeq analysis comparing infected and uninfected cells. (A, B) Venn diagrams comparing DEGs with increased and decreased abundance between Tlr2-/- and wild-type macrophages. (C, D) To explore the function of DEGs analyzed in the Venn diagram, GO term enrichment analysis was performed. Asterisks represent significant differences with p < 0.05 in Fisher’s exact test. (E, F) Expression of top 20 highly upregulated or downregulated TLR2-depdent genes. TLR2-dependent DEGs were ranked according to fold-changes between infected and uninfected wild-type. WT, wild-type; KO, Tlr2-/-.

https://doi.org/10.1371/journal.pone.0303453.g002

Reference

  1. 1. Umeda K, Tanaka S, Ihara F, Yamagishi J, Suzuki Y, Nishikawa Y (2017) Transcriptional profiling of Toll-like receptor 2-deficient primary murine brain cells during Toxoplasma gondii infection. PLoS ONE 12(11): e0187703. https://doi.org/10.1371/journal.pone.0187703

Citation: Umeda K, Tanaka S, Ihara F, Yamagishi J, Suzuki Y, Nishikawa Y (2024) Correction: Transcriptional profiling of Toll-like receptor 2-deficient primary murine brain cells during Toxoplasma gondii infection. PLoS ONE 19(5): e0303453. https://doi.org/10.1371/journal.pone.0303453

Published: May 2, 2024

Copyright: © 2024 Umeda et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.