Advertisement
Browse Subject Areas
?

Click through the PLOS taxonomy to find articles in your field.

For more information about PLOS Subject Areas, click here.

  • Loading metrics

Open Access

Correction

Correction: Adeno-Associated Viral Vector Serotype 5 Poorly Transduces Liver in Rat Models

  • The PLOS ONE Staff

Figure 2 is incorrect. The authors have provided a corrected version here.

thumbnail
Download:
Figure 2. scAAV2/1, 5 and 8 vectors biodistribution and UGT1A1 mRNA expression levels in liver tissue.

(A) UGT1A1 transgene copy number per diploid genome equivalent (dGE) in liver, lung, testis, spleen, heart, kidney and duodenum of male Gunn rats at 62 weeks after portal vein injection of scAAV1, 5 or 8 as calculated by the ratio of UGT1A1 copies and the rat β-actin gene copies in 100 ng of DNA as quantified by qPCR. (B) Relative UGT1A1 mRNA levels in liver quantified by qPCR and normalized with 18S rRNA levels. The results obtained with AAV5 are statistically significant different (p<0.001) compared to the obtained with AAV1 and AAV8 using the nonparametric Mann–Whitney test.

https://doi.org/10.1371/journal.pone.0082597.g002

Reference

  1. 1. Montenegro-Miranda PS, Pañeda A, ten Bloemendaal L, Duijst S, de Waart DR, et al. (2013) Adeno-Associated Viral Vector Serotype 5 Poorly Transduces Liver in Rat Models. PLoS ONE 8(12): e82597

Citation: The PLOS ONE Staff (2014) Correction: Adeno-Associated Viral Vector Serotype 5 Poorly Transduces Liver in Rat Models. PLoS ONE 9(6): e101857. https://doi.org/10.1371/journal.pone.0101857

Published: June 26, 2014

Copyright: © 2014 The PLOS ONE Staff. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.