Fig 1.
MMSE = Mini-mental state examination, MoCA = Montreal Cognitive Assessment, CDR = Clinical dementia rating, HC = Healthy control, MCI = Mild cognitive impairment, AD = Alzheimer’s disease, sMRI = structural MRI, fMRI = functional MRI, DTI = diffusion tensor imaging, 1H-MRS = magnetic resonance spectroscopy.
Fig 2.
T1-weighted skull-stripped images of a healthy volunteer in the axial (A), coronal (B), and sagittal (C) planes of a volunteer.
Fig 3.
rs-fMRI of a healthy volunteer.
Three-dimensional MNI surface renders and mean T1 weighted image of rs-fMRI.
Fig 4.
A midsagittal T1-weighted image of the brain of a healthy volunteer.
A 2 x 2 x 2 cm3 voxel placement in the PCC/Prec is shown in A. The proton spectra obtained from the region with a TE of 30 ms depicts the NAA, Cr, and mI metabolites in B.
Fig 5.
Axial DTI maps of colour FA (A), non-colour FA (B), ADC (C), and trace-weighted (D).