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Fig 1.

DOC screen.

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Fig 2.

DOC study patient flow.

Impairment on the reference standard was determined using the two cut-point regression method.

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Table 1.

Feasibility and validity patient characteristics.

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Table 1 Expand

Table 2.

DOC screen and MoCA feasibility.

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Table 3.

DOC-Mood scores to impairment on the SCID-D.

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Table 4.

DOC-Apnea scores to impairment on the polysomnogram.

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Table 5.

DOC-Cog scores to impairment on the neuropsychological test battery.

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Table 6.

MoCA scores to impairment on the NTP.

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Fig 3.

ROC curves displaying DOC mood optimal diagnostic cut-points, for high sensitivity and specificity and diagnostic cut-points with a logistic regression applied, controlling for age, sex and education.

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Table 7.

DOC-Mood results.

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Table 7 Expand

Fig 4.

ROC curves displaying DOC apnea diagnostic cut-points, for high sensitivity and specificity and diagnostic cut-points with a logistic regression applied, controlling for age, sex and BMI.

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Fig 4 Expand

Table 8.

DOC-Apnea results.

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Table 8 Expand

Fig 5.

ROC curves displaying DOC cog diagnostic cut-points, for high sensitivity and specificity and with diagnostic cut-points with a logistic regression applied, controlling for age, sex and education.

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Fig 5 Expand

Table 9.

DOC-Cog results.

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Table 9 Expand